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17 results on '"Paolucci V"'

3. OC-0501 Chemo-RT plus induction or consolidation chemotherapy for rectal cancer: a randomised phase 2 trial

Author

Fokas, E., primary, Allgäuer, M., additional, Polat, B., additional, Klautke, G., additional, Grabenbauer, G., additional, Fietkau, R., additional, Kuhnt, T., additional, Staib, L., additional, Brunner, T., additional, Grosu, A.L., additional, Schmiegel, W., additional, Jacobasch, L., additional, Weitz, J., additional, Folprecht, G., additional, Schleska-Lange, A., additional, Grützmann, R., additional, Schwarzbach, M., additional, Paolucci, V., additional, Bechstein, W.O., additional, Friede, T., additional, Ghadimi, M., additional, Hofheinz, R.D., additional, and Rödel, C., additional

Published
2019
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8. Gemcitabine as single agent second line treatment in patients with advanced wild-type EGFR, negative ALK non-small cell lung cancer: a retrospective study

Author

Rinaldi, S., primary, Morgese, F., additional, Torniai, M., additional, Savini, A., additional, Barbotti, F., additional, Pirani, F., additional, Leoni, G., additional, Grohè, C., additional, Newsom-Davis, T., additional, Paolucci, V., additional, Bower, M., additional, Fiordoliva, I., additional, and Berardi, R., additional

Published
2016
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9. Bone metastases (BMs) in patients with advanced non-small cell lung cancer (NSCLC): do they always correlate with poor prognosis?

Author

Rinaldi, S., primary, Berardi, R., additional, Santoni, M., additional, Morgese, F., additional, Torniai, M., additional, Fiordoliva, I., additional, Caramanti, M., additional, Paolucci, V., additional, Savini, A., additional, Onofri, A., additional, Santini, D., additional, Armento, G., additional, and Cascinu, S., additional

Published
2015
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10. Hyponatremia normalization as an independent prognostic factor in patients with advanced non-small cell lung cancer treated with first-line therapy

Author

Caramanti, M., primary, Berardi, R., additional, Santoni, M., additional, Newsom-Davis, T., additional, Rinaldi, S., additional, Savini, A., additional, Tiberi, M., additional, Morgese, F., additional, Torniai, M., additional, Fiordoliva, I., additional, Paolucci, V., additional, Pistelli, M., additional, Onofri, A., additional, Bower, M., additional, and Cascinu, S., additional

Published
2015
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12. Impact and prognostic role of single-neucleotide polymorphisms (SNPs) in thymic lesions

Author

Torniai, M., primary, Berardi, R., additional, Brunelli, A., additional, Pagliaretta, S., additional, Paolucci, V., additional, Conti, A., additional, Goteri, G., additional, Refai, M., additional, Pompili, C., additional, Marcantognini, G., additional, Morgese, F., additional, Savini, A., additional, Caramanti, M., additional, Santoni, M., additional, Zizzi, A., additional, Mazzanti, P., additional, Onofri, A., additional, Sabbatini, A., additional, Scarpelli, M., additional, and Cascinu, S., additional

Published
2015
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17. Groundwater mixing in a heterogeneous multilayer aquifer driven by geogenic CO2 fluxes: Evidence from chemical and isotopic composition of Ferrarelle waters (Riardo Plain, southern Italy)

Author

Elisa Sacchi, D. Tedesco, Maurizio Sirna, E. Cuoco, Erica Lynn Maletic, Vittorio Paolucci, Stefano De Francesco, Thomas H. Darrah, Cuoco, E., Sacchi, E., De Francesco, S., Paolucci, V., Maletic, E., Darrah, T. H., Sirna, M., and Tedesco, D.

Subjects
geography, geography.geographical_feature_category, δ18O, Geochemistry, Aquifer, Crust, 010501 environmental sciences, 010502 geochemistry & geophysics, 01 natural sciences, Pollution, Volcano, Geochemistry and Petrology, Environmental Chemistry, Upwelling, Aqueous geochemistry, Groundwater, Geology, 0105 earth and related environmental sciences, Geochemical modeling
Abstract

The successful management of carbon in the Earth's crust is critical for mitigating the increase of anthropogenic CO2 in the atmosphere. Carbon Capture and Storage (CCS) requires an understanding of the behavior of carbon in the crust and the development of robust monitoring techniques to constrain the movement, mechanisms, and pathways for any potential CO2 leakage. Here, we examine an aquifer from the Riardo Plain (Campania Region, southern Italy), which serves as a suitable natural analogue for CO2 migration to the critical zone (i.e., shallow crust and aquifers) and as a case study to evaluate the geochemical processes that occur when CO2-saturated fluids mix with freshwater in shallow aquifers. We investigate the behavior of various geochemical constituents (major and trace elements, δ18O–H2O, δ13C-DIC, and Rn content). Water from this area has a high degree of mineralization (EC 2500–3000 μS/cm), high HCO3- (~2.5 g/L), is saturated with respect to CaCO3, and is enriched in alkali ions (e.g., Na+ + K+). The high degree of mineralization occurs in groundwater that discharges from the basal aquifer of the Roccamonfina volcanic edifice (~6 km NW), with vast CO2 inputs that promote host rock leaching. Superficial volcanic aquifers are recharged by fresh meteoric precipitation when groundwater flows from carbonates at the edge of the plain to aquifers hosted in the southeastern slope of the Roccamonfina volcano. The presence of normal faults in this area permits natural upwelling of CO2-rich groundwater, which locally mixes with shallow freshwater present within the upper volcanic succession. Significant (R > 0.8) linear correlations between conservative elements suggest that groundwater geochemistry is dominated by a mixture of two main endmembers: (i) deep/mineralized waters and (ii) shallow/diluted waters. The intrusion of freshwater to volcanic aquifers induces oxidation, leading to adsorption of select elements (e.g., As and Ba) onto Fe-oxyhydroxide precipitates within these aquifers. Geochemical modeling suggests that CO2 saturation approaches 3 g/L, which agrees with direct measurements of CO2 flux. We conclude that our conceptual geochemical model helps to constrain mixing of CO2 with freshwater and to diagnose the secondary geochemical processes that influence aqueous geochemistry within CO2-influenced groundwater.

Published
2020
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