1. Vascular branching point counts using photoacoustic imaging in the superficial layer of the breast: A potential biomarker for breast cancer
- Author
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Yasufumi Asao, Kaori Togashi, Aya Yoshikawa, Tsuyoshi Shiina, Takayuki Yagi, Yoshiaki Matsumoto, Masahiro Kawashima, Takaki Sakurai, Hironori Haga, Toshifumi Fukui, Masae Torii, Elham Fakhrejahani, Masahiro Takada, Mariko Tokiwa, Masako Kataoka, Masakazu Toi, Nobuko Kawaguchi-Sakita, Shotaro Kanao, Yoshie Nakayama, and Iku Yamaga
- Subjects
BP, blood pressure ,medicine.drug_class ,lcsh:QC221-246 ,Photoacoustic imaging in biomedicine ,01 natural sciences ,030218 nuclear medicine & medical imaging ,010309 optics ,03 medical and health sciences ,Breast cancer ,0302 clinical medicine ,0103 physical sciences ,medicine ,lcsh:QC350-467 ,Radiology, Nuclear Medicine and imaging ,In patient ,DCIS, ductal carcinoma in situ ,skin and connective tissue diseases ,US, ultrasonography ,business.industry ,VBP, vessel branching point ,Vessel branching points ,Cancer ,Biomarker ,Branching points ,medicine.disease ,lcsh:QC1-999 ,Atomic and Molecular Physics, and Optics ,HDA, hemispherical detector array ,PAI, photoacoustic imaging ,Estrogen ,Potential biomarkers ,lcsh:Acoustics. Sound ,Vasculature ,Biomarker (medicine) ,Photoacoustic imaging ,Nuclear medicine ,business ,MRI, magnetic resonance imaging ,lcsh:Physics ,lcsh:Optics. Light ,Research Article - Abstract
This study aimed to identify the characteristics of the vascular network in the superficial subcutaneous layer of the breast and to analyze differences between breasts with cancer and contralateral unaffected breasts using vessel branching points (VBPs) detected by three-dimensional photoacoustic imaging with a hemispherical detector array. In 22 patients with unilateral breast cancer, the average VBP counts to a depth of 7 mm below the skin surface were significantly greater in breasts with cancer than in the contralateral unaffected breasts (p
- Published
- 2018