74 results on '"Silke, John"'
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2. Interferon-γ primes macrophages for pathogen ligand-induced killing via a caspase-8 and mitochondrial cell death pathway
3. Unleashing TNF cytotoxicity to enhance cancer immunotherapy
4. Targeting the Extrinsic Pathway of Hepatocyte Apoptosis Promotes Clearance of Plasmodium Liver Infection
5. Preliminary experience with high-density electroanatomical mapping for ablation of atrial fibrillation – Comparison of mini-basket and novel open irrigated magnetic ablation catheter in consecutive patients
6. 2007 - RIPPING LEUKEMIAS APART: THE ROLE OF RIP KINASE 1 IN ACUTE MYELOID LEUKEMIA
7. TARGETING MULTIDRUG RESISTANCE PROTEIN 1 (MDR1) POTENTIATES SMAC-MIMETIC THERAPY TO KILL LEUKEMIC STEM CELLS AND OVERCOME RESISTANCE IN ACUTE MYELOID LEUKEMIA
8. RIPK1 and Caspase-8 Ensure Chromosome Stability Independently of Their Role in Cell Death and Inflammation
9. The Mitochondrial Apoptotic Effectors BAX/BAK Activate Caspase-3 and -7 to Trigger NLRP3 Inflammasome and Caspase-8 Driven IL-1β Activation
10. Catheter ablation of atrial fibrillation supported by novel nonfluoroscopic 4D navigation technology
11. The Walrus and the Carpenter: Complex Regulation of Tumor Immunity in Colorectal Cancer
12. IAPs Regulate Distinct Innate Immune Pathways to Co-ordinate the Response to Bacterial Peptidoglycans
13. Ubiquitin-Mediated Regulation of RIPK1 Kinase Activity Independent of IKK and MK2
14. Inhibitor of Apoptosis Proteins (IAPs) Limit RIPK1-Mediated Skin Inflammation
15. The TNF Receptor Superfamily-NF-κB Axis Is Critical to Maintain Effector Regulatory T Cells in Lymphoid and Non-lymphoid Tissues
16. Usefulness of Dronedarone in Patients With Atrial Arrhythmias
17. Tumor necrosis factor (TNF) signaling, but not TWEAK (TNF-like weak inducer of apoptosis)-triggered cIAP1 (cellular inhibitor of apoptosis protein 1) degradation, requires cIAP1 RING dimerization and E2 binding.
18. XIAP Loss Triggers RIPK3- and Caspase-8-Driven IL-1β Activation and Cell Death as a Consequence of TLR-MyD88-Induced cIAP1-TRAF2 Degradation
19. MK2 Phosphorylates RIPK1 to Prevent TNF-Induced Cell Death
20. Engineered Exosomes as Vehicles for Biologically Active Proteins
21. ‘Did He Who Made the Lamb Make Thee?’ New Developments in Treating the ‘Fearful Symmetry’ of Acute Myeloid Leukemia
22. Inhibitor of Apoptosis Protein-1 Regulates Tumor Necrosis Factor–Mediated Destruction of Intestinal Epithelial Cells
23. Jekyll & Hyde: The Other Life of the Death Ligand TRAIL
24. The Pseudokinase MLKL and the Kinase RIPK3 Have Distinct Roles in Autoimmune Disease Caused by Loss of Death-Receptor-Induced Apoptosis
25. Targeting p38 or MK2 Enhances the Anti-Leukemic Activity of Smac-Mimetics
26. Killing Lymphoma with Smac-Mimetics: As Easy as ABC?
27. The importance of being chaperoned: HSP90 and necroptosis
28. In TNF-stimulated cells, RIPK1 promotes cell survival by stabilizing TRAF2 and cIAP1, which limits induction of non-canonical NF-κB and activation of caspase-8.
29. Ivabradine for rate control in atrial fibrillation
30. Targeting of Fn14 Prevents Cancer-Induced Cachexia and Prolongs Survival
31. Nedd4 Family Interacting Protein 1 (Ndfip1) Is Required for Ubiquitination and Nuclear Trafficking of BRCA1-associated ATM Activator 1 (BRAT1) during the DNA Damage Response
32. IAP gene deletion and conditional knockout models
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34. 193
35. 47
36. HOIP Deficiency Causes Embryonic Lethality by Aberrant TNFR1-Mediated Endothelial Cell Death
37. RIPK1 Regulates RIPK3-MLKL-Driven Systemic Inflammation and Emergency Hematopoiesis
38. The Pseudokinase MLKL Mediates Necroptosis via a Molecular Switch Mechanism
39. Masters, marionettes and modulators: intersection of pathogen virulence factors and mammalian death receptor signaling
40. VERNAKALANT FACILITATED ELECTRICAL CARDIOVERSION: A RANDOMIZED, OPEN LABEL PILOT STUDY COMPARING INTRAVENOUS VERNAKALANT AND AMIODARONE FOR DRUG-ENHANCED ELECTRICAL CARDIOVERSION OF CARDIOVERSION-RESISTANT ATRIAL FIBRILLATION
41. The Ubiquitin Ligase XIAP Recruits LUBAC for NOD2 Signaling in Inflammation and Innate Immunity
42. Differential regulation of Nedd4 ubiquitin ligases and their adaptor protein Ndfip1 in a rat model of ischemic stroke
43. Inhibitor of Apoptosis Proteins Limit RIP3 Kinase-Dependent Interleukin-1 Activation
44. The regulation of TNF signalling: what a tangled web we weave
45. Smac Mimetics Activate the E3 Ligase Activity of cIAP1 Protein by Promoting RING Domain Dimerization
46. In TNF-stimulated Cells, RIPK1 Promotes Cell Survival by Stabilizing TRAF2 and cIAP1, which Limits Induction of Non-canonical NF-κB and Activation of Caspase-8
47. Systematic In Vivo RNAi Analysis Identifies IAPs as NEDD8-E3 Ligases
48. Asymmetric Recruitment of cIAPs by TRAF2
49. Tumor Necrosis Factor (TNF) Signaling, but Not TWEAK (TNF-like Weak Inducer of Apoptosis)-triggered cIAP1 (Cellular Inhibitor of Apoptosis Protein 1) Degradation, Requires cIAP1 RING Dimerization and E2 Binding
50. Dysregulation of hepatocyte cell cycle and cell viability by hepatitis B virus
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