57 results on '"Sullenger, Bruce A."'
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2. HTRS2023.O6B.2 Allosteric regulation of coagulation factor IXa
3. Rapid Molecular Imaging of Active Thrombi In Vivo Using Aptamer-Antidote Probes
4. Aptamer-programmable adeno-associated viral vectors as a novel platform for cell-specific gene transfer
5. Mixed-surface polyamidoamine polymer variants retain nucleic acid-scavenger ability with reduced toxicity
6. Targeting DAMPs with nucleic acid scavengers to treat lupus
7. DAMPs/PAMPs induce monocytic TLR activation and tolerance in COVID-19 patients; nucleic acid binding scavengers can counteract such TLR agonists
8. Aptamer-based factor IXa inhibition preserves hemostasis and prevents thrombosis in a piglet model of ECMO
9. Generation of an anticoagulant aptamer that targets factor V/Va and disrupts the FVa-membrane interaction in normal and COVID-19 patient samples
10. β-Cyclodextrin-containing polymer treatment of cutaneous lupus and influenza improves outcomes
11. Utilizing Directed Evolution to Interrogate and Optimize CRISPR/Cas Guide RNA Scaffolds
12. Breast cancer-derived DAMPs enhance cell invasion and metastasis, while nucleic acid scavengers mitigate these effects
13. Controlling cancer-induced inflammation with a nucleic acid scavenger prevents lung metastasis in murine models of breast cancer
14. Enhancing cardiac reprogramming via synthetic RNA oligonucleotides
15. RGEN Editing of RNA and DNA: The Long and Winding Road from Catalytic RNAs to CRISPR to the Clinic
16. Aptamers as Reversible Sorting Ligands for Preparation of Cells in Their Native State
17. Nucleic-Acid Scavengers Mitigate Breast Cancer Induced Inflammation, Invasion, and Metastasis
18. Preclinical Development of a vWF Aptamer to Limit Thrombosis and Engender Arterial Recanalization of Occluded Vessels
19. Anti-PEG Antibodies Inhibit the Anticoagulant Activity of PEGylated Aptamers
20. Toll-like receptor activation as a biomarker in traumatically injured patients
21. Polymer-Mediated Inhibition of Pro-invasive Nucleic Acid DAMPs and Microvesicles Limits Pancreatic Cancer Metastasis
22. Differential Induction of Immunogenic Cell Death and Interferon Expression in Cancer Cells by Structured ssRNAs
23. Nucleic acid scavenging microfiber mesh inhibits trauma-induced inflammation and thrombosis
24. Toll-Like Receptor Signaling as a Prognostic Tool in Trauma Patients
25. Differential effects of toll-like receptor stimulation on mRNA-driven myogenic conversion of human and mouse fibroblasts
26. Pre-existing anti–polyethylene glycol antibody linked to first-exposure allergic reactions to pegnivacogin, a PEGylated RNA aptamer
27. In Vivo Selection Against Human Colorectal Cancer Xenografts Identifies an Aptamer That Targets RNA Helicase Protein DHX9
28. Immobilization of nucleic acid binding polymers as anti-inflammatory agent in autoimmunity
29. 65. A Novel Aptamer Targeting Agent for Prostate Cancer
30. 66. Identification and Characterization of a B Cell Aptamer That Targets Diffuse Large B Cell Lymphoma (DLBCL) and Chronic Myelogenous Leukemia (CML)
31. 272. Nucleic Acid Scavenging Nanofibers as Anti-Inflammatory Meshes
32. Probing the Coagulation Pathway with Aptamers Identifies Combinations that Synergistically Inhibit Blood Clot Formation
33. Increased anticoagulant activity of thrombin-binding DNA aptamers by nanoscale organization on DNA nanostructures
34. Potent Anticoagulant Aptamer Directed against Factor IXa Blocks Macromolecular Substrate Interaction
35. Rapidly Regulating Platelet Activity In Vivo With an Antidote Controlled Platelet Inhibitor
36. An Anticoagulant RNA Aptamer That Inhibits Proteinase-Cofactor Interactions within Prothrombinase
37. RNA Aptamer Blockade of Osteopontin Inhibits Growth and Metastasis of MDA-MB231 Breast Cancer Cells
38. 45. Molecular-based translational medicine
39. Assembling OX40 Aptamers on a Molecular Scaffold to Create a Receptor-Activating Aptamer
40. Inhibition of In Vivo Tumor Angiogenesis and Growth Via Systemic Delivery of an Angiopoietin 2-Specific RNA Aptamer
41. RNA Aptamer-targeted Inhibition of NF-κB Suppresses Non-small Cell Lung Cancer Resistance to Doxorubicin
42. In Vivo Reprogramming of hTERT by Trans-splicing Ribozyme to Target Tumor Cells
43. NF-κB inhibition by an adenovirus expressed aptamer sensitizes TNFα-induced apoptosis
44. A Novel Antidote-Controlled Anticoagulant Reduces Thrombin Generation and Inflammation and Improves Cardiac Function in Cardiopulmonary Bypass Surgery
45. 1028. Use of Antisense Oligonucleotides To Restore Activity in Mutant p53
46. 83. Cell_Type Specific Delivery of siRNAs with Aptamer_siRNA Chimeras
47. Targeted inhibition of αvβ3 integrin with an RNA aptamer impairs endothelial cell growth and survival
48. Retargeting mobile group II introns to repair mutant genes
49. The potential of aptamers as anticoagulants
50. Ribozyme-Mediated Induction of Apoptosis in Human Cancer Cells by Targeted Repair of Mutant p53 RNA
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