1. Stress Signaling: Serotonin Spreads Systemic Stress
- Author
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Todd Lamitina and Arjumand Ghazi
- Subjects
Serotonin ,medicine.medical_specialty ,Gonad ,Cell ,Biology ,Article ,General Biochemistry, Genetics and Molecular Biology ,Internal medicine ,medicine ,Animals ,Heat shock ,Caenorhabditis elegans ,Caenorhabditis elegans Proteins ,Regulation of gene expression ,Agricultural and Biological Sciences(all) ,Biochemistry, Genetics and Molecular Biology(all) ,Stress signaling ,Serotonin metabolism ,Cell biology ,Endocrinology ,medicine.anatomical_structure ,Gene Expression Regulation ,Systemic stress ,General Agricultural and Biological Sciences ,Heat-Shock Response ,Transcription Factors - Abstract
SummaryCells respond to elevated temperatures through a well-characterized heat-shock response that enables short-term survival, long-term adaptation and mitigation of macromolecular damage. New work reveals a cell non-autonomous layer of stress-response regulation between neurons and the gonad involving serotonin.
- Published
- 2015
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