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281 results on '"Trojanowski, John"'

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1. MAPT H2 haplotype and risk of Pick's disease in the Pick's disease International Consortium: a genetic association study

2. Amyloid-Beta (Aβ) Plaques Promote Seeding and Spreading of Alpha-Synuclein and Tau in a Mouse Model of Lewy Body Disorders with Aβ Pathology

3. Circular-SWAT for deep learning based diagnostic classification of Alzheimer's disease: application to metabolome data

4. Prioritization of Drug Targets for Neurodegenerative Diseases by Integrating Genetic and Proteomic Data From Brain and Blood

6. Natural speech markers of Alzheimer's disease co-pathology in Lewy body dementias

7. Non-tremor motor dysfunction in Lewy body dementias is associated with AD biomarkers

9. Tau interactome maps synaptic and mitochondrial processes associated with neurodegeneration

10. Ex vivo MRI and histopathology detect novel iron-rich cortical inflammation in frontotemporal lobar degeneration with tau versus TDP-43 pathology

11. Plasma Phosphorylated Tau181 is a Biomarker of Alzheimer's Disease Pathology and Associated with Cognitive and Functional Decline

12. Synapsin-caveolin-1 gene therapy preserves neuronal and synaptic morphology and prevents neurodegeneration in a mouse model of AD

13. Gene Expression Imputation Across Multiple Tissue Types Provides Insight Into the Genetic Architecture of Frontotemporal Dementia and Its Clinical Subtypes

14. Pathogenic Huntingtin Repeat Expansions in Patients with Frontotemporal Dementia and Amyotrophic Lateral Sclerosis

15. High-Contrast In Vivo Imaging of Tau Pathologies in Alzheimer’s and Non-Alzheimer’s Disease Tauopathies

17. Characterization of tau binding by gosuranemab

18. Multimodal in vivo and postmortem assessments of tau in Lewy body disorders

19. Tau Pathology Drives Dementia Risk-Associated Gene Networks toward Chronic Inflammatory States and Immunosuppression

20. Metabolic Network Analysis Reveals Altered Bile Acid Synthesis and Metabolism in Alzheimer’s Disease

22. Compound screening in cell-based models of tau inclusion formation: Comparison of primary neuron and HEK293 cell assays

23. Characterization of novel conformation-selective α-synuclein antibodies as potential immunotherapeutic agents for Parkinson's disease

24. Glucocerebrosidase Activity Modulates Neuronal Susceptibility to Pathological α-Synuclein Insult

25. Clinical and dopamine transporter imaging characteristics of non-manifest LRRK2 and GBA mutation carriers in the Parkinson's Progression Markers Initiative (PPMI): a cross-sectional study

26. Amyloid-Beta (Aβ) Plaques Promote Seeding and Spreading of Alpha-Synuclein and Tau in a Mouse Model of Lewy Body Disorders with Aβ Pathology

27. Tracking white matter degeneration in asymptomatic and symptomatic MAPT mutation carriers

29. Humanization of the entire murine Mapt gene provides a murine model of pathological human tau propagation

31. Heritability and genetic variance of dementia with Lewy bodies

32. Feasibility and safety of lumbar puncture in the Parkinson's disease research participants: Parkinson's Progression Marker Initiative (PPMI)

33. Reduction of matrix metalloproteinase 9 (MMP-9) protects motor neurons from TDP-43-triggered death in rNLS8 mice

34. Exome Sequencing Reveals VCP Mutations as a Cause of Familial ALS

35. A comprehensive screening of copy number variability in dementia with Lewy bodies

36. Primum non nocere: a call for balance when reporting on CTE

37. UNC13A polymorphism contributes to frontotemporal disease in sporadic amyotrophic lateral sclerosis

38. LRP10 in α-synucleinopathies

39. LRP10 in α-synucleinopathies

40. Design, synthesis and evaluation of photoactivatable derivatives of microtubule (MT)-active [1,2,4]triazolo[1,5-a]pyrimidines

41. Potential genetic modifiers of disease risk and age at onset in patients with frontotemporal lobar degeneration and GRN mutations: a genome-wide association study

42. Transethnic genome-wide scan identifies novel Alzheimer's disease loci

43. Body mass index is associated with biological CSF markers of core brain pathology of Alzheimer's disease

44. Neocortical origin and progression of gray matter atrophy in nonamnestic Alzheimer's disease

45. Investigating the genetic architecture of dementia with Lewy bodies: a two-stage genome-wide association study

46. Genome-Wide Analyses Identify KIF5A as a Novel ALS Gene

47. TDP-43 Promotes Neurodegeneration by Impairing Chromatin Remodeling

48. Targeted neurogenesis pathway-based gene analysis identifies ADORA2A associated with hippocampal volume in mild cognitive impairment and Alzheimer's disease

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