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Purpose To investigate the diagnostic accuracy of 3.0-T diffusion-weighted imaging (DWI) for detection of prostate cancer by using different b -values. Methods Seventy-three patients underwent magnetic resonance imaging (MRI) at 3.0 T. Three MRI sets were reviewed by two radiologists: MRI and DWI ( b =500s/mm 2 ) (protocol A), MRI and DWI ( b =1000s/mm 2 ) (protocol B), and MRI and DWI ( b =2000s/mm 2 ) (protocol C). Areas under the receiver operating characteristic curve (AUCs) were calculated. Results The mean of the AUCs in protocol C was larger than those in protocol A and in protocol B ( P Conclusion DWI ( b =2000s/mm 2 ) at 3.0 T can improve the diagnostic accuracy for detection of prostate cancer.

Magnetic resonance imaging with phased-array coils was performed in patients with prostate carcinoma before and after hormonal therapy, radiation therapy or radical prostatectomy to evaluate therapeutic effect and recurrence. After hormonal therapy, the prostate gland, seminal vesicle and primary site of tumor usually decrease in size with variable T2 hypointensity. Recurrent or residual tumors after hormonal therapy usually represent T2 hyperintense lesions compared to the hypointensity of the surrounding tissues. Changes of metastatic sites after therapy were also demonstrated.