1. [Role of antithrombin iii in cardiac surgery].
- Author
-
Muedra V, Barettino D, and D'Ocón P
- Subjects
- Antithrombin III analysis, Antithrombin III therapeutic use, Antithrombin III Deficiency drug therapy, Antithrombin III Deficiency etiology, Antithrombin III Deficiency mortality, Extracorporeal Circulation adverse effects, Humans, Systemic Inflammatory Response Syndrome etiology, Antithrombin III physiology, Cardiac Surgical Procedures
- Abstract
Coagulation of blood is of multidisciplinary interest. Cardiac surgery produces major changes in the delicate balance between pro-and anti-coagulant serum factors. The role of antithrombin iii has been analysed after finding evidence that associated decreased levels of protein activity to postoperative morbidity and mortality. Supplementing exogenous antithrombin is considered with the aim of optimising outcomes. Its intrinsic anticoagulant and anti-inflammatory properties have stimulated a growing interest, and suggests new lines of research., (Copyright © 2012 Sociedad Española de Anestesiología, Reanimación y Terapéutica del Dolor. Published by Elsevier España. All rights reserved.)
- Published
- 2013
- Full Text
- View/download PDF