1. Disseminated cryptococcosis manifested as a single tumor in an immunocompetent patient, similar to the cutaneous primary forms.
- Author
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Amaral DM, Rocha RC, Carneiro LE, Vasconcelos DM, and Abreu MA
- Subjects
- Aged, Biopsy, Cryptococcosis immunology, Cryptococcosis microbiology, Cryptococcus neoformans isolation & purification, Dermatomycoses immunology, Dermatomycoses microbiology, Humans, Male, Opportunistic Infections microbiology, Skin microbiology, Skin pathology, Cryptococcosis pathology, Dermatomycoses pathology, Immunocompromised Host
- Abstract
Cryptococcosis is a fungal infection caused by Cryptococcus neoformans that tends to affect immunocompromised individuals. The fungi are mostly acquired by inhalation, which leads to an initial pulmonary infection. Later, other organs - such as the central nervous system and the skin - can be affected by hematogenous spread. In addition, cutaneous contamination can occur by primary inoculation after injuries (primary cutaneous cryptococcosis), whose diagnosis is defined based on the absence of systemic involvement. The clinical presentation of cutaneous forms typically vary according to the infection mode. We report an unusual case of disseminated cryptococcosis in an immunocompetent patient with cutaneous lesions similar to those caused by primary inoculation. This clinical picture leads us to question the definition of primary cutaneous cryptococcosis established in the literature.
- Published
- 2016
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