1. Rheumatoid vasculitis: study of 41 cases.
- Author
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Olivé A, Riveros A, Juárez P, Morales-Ivorra I, Holgado S, and Narváez J
- Subjects
- Female, Humans, Immunosuppressive Agents therapeutic use, Male, Retrospective Studies, Arthritis, Rheumatoid diagnosis, Arthritis, Rheumatoid drug therapy, Arthritis, Rheumatoid epidemiology, Rheumatoid Vasculitis diagnosis, Rheumatoid Vasculitis epidemiology, Rheumatoid Vasculitis etiology, Vasculitis diagnosis, Vasculitis epidemiology
- Abstract
Aim: To describe the clinical manifestations, evolution and treatment of patients with rheumatoid vasculitis., Methods: Retrospective study (1975-2017) of all patients diagnosed with rheumatoid vasculitis in 2 Rheumatology Services., Results: A total of 41 patients were included, 17 (41.5%) males and 24 (58.5%) females; mean age at diagnosis: 67 ± 9 years; duration of rheumatoid arthritis: 10 ± 8.3 years. Most patients had erosive disease, 33 (80%). Rheumatoid factor and anticitrullinated antibodies were positive in all patients. Constitutional symptoms were present in 30 (73%) patients and extra-articular manifestations in 17 (41%) patients. The clinical manifestations of rheumatoid vasculitis were mainly: cutaneous 28 (68%), and polyneuritis 26 (63%). All patients were treated with glucocorticoids. An immunosuppressant was associated in 24 (58.5%) patients. Five (12%) patients were treated with the association of glucocorticoids and a biologic treatment. The mortality after 2years of follow-up was 33%, the most common causes being infection and progression of the vasculitis. The frequency of rheumatoid vasculitis has decreased over the last decade., Conclusion: The clinical manifestations of rheumatoid vasculitis were similar to previous studies. The frequency of rheumatoid vasculitis seems to decrease. However, the clinical picture and severity remains invariable., (Copyright © 2020 Elsevier España, S.L.U. All rights reserved.)
- Published
- 2020
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