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86 results on '"Lifton, Richard P"'

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1. De novo variants implicate chromatin modification, transcriptional regulation, and retinoic acid signaling in syndromic craniosynostosis

2. Whole-exome sequencing reveals damaging gene variants associated with hypoalphalipoproteinemia

3. Centers for Mendelian Genomics: A decade of facilitating gene discovery

4. Generation of Monogenic Candidate Genes for Human Nephrotic Syndrome Using 3 Independent Approaches

5. Recessive Mutations in SYNPO2 as a Candidate of Monogenic Nephrotic Syndrome

6. DAAM2 Variants Cause Nephrotic Syndrome via Actin Dysregulation

7. Exome Sequencing Implicates Impaired GABA Signaling and Neuronal Ion Transport in Trigeminal Neuralgia

8. Mutations of the Transcriptional Corepressor ZMYM2 Cause Syndromic Urinary Tract Malformations

9. Systems Analysis Implicates WAVE2 Complex in the Pathogenesis of Developmental Left-Sided Obstructive Heart Defects

10. Whole exome sequencing identified ATP6V1C2 as a novel candidate gene for recessive distal renal tubular acidosis

11. Insights into genetics, human biology and disease gleaned from family based genomic studies

12. Monogenic causes of chronic kidney disease in adults

13. Mutations in Chromatin Modifier and Ephrin Signaling Genes in Vein of Galen Malformation

14. Mutations in PERP Cause Dominant and Recessive Keratoderma

15. Mutations of ADAMTS9 Cause Nephronophthisis-Related Ciliopathy

17. CARD14-associated papulosquamous eruption: A spectrum including features of psoriasis and pityriasis rubra pilaris

18. C-terminally truncated, kidney-specific variants of the WNK4 kinase lack several sites that regulate its activity

19. The Psychiatric Cell Map Initiative: A Convergent Systems Biological Approach to Illuminating Key Molecular Pathways in Neuropsychiatric Disorders

20. De Novo Mutation in Genes Regulating Neural Stem Cell Fate in Human Congenital Hydrocephalus

21. Whole exome sequencing frequently detects a monogenic cause in early onset nephrolithiasis and nephrocalcinosis

22. Exome-wide Association Study Identifies GREB1L Mutations in Congenital Kidney Malformations

24. Exome Sequencing Identifies Biallelic MSH3 Germline Mutations as a Recessive Subtype of Colorectal Adenomatous Polyposis

25. Mutations in the Histone Modifier PRDM6 Are Associated with Isolated Nonsyndromic Patent Ductus Arteriosus

26. Whole exome sequencing identifies causative mutations in the majority of consanguineous or familial cases with childhood-onset increased renal echogenicity

28. The Genetic Basis of Mendelian Phenotypes: Discoveries, Challenges, and Opportunities

29. Mutations in TBX18 Cause Dominant Urinary Tract Malformations via Transcriptional Dysregulation of Ureter Development

31. DCDC2 Mutations Cause a Renal-Hepatic Ciliopathy by Disrupting Wnt Signaling

32. Mutations in KATNB1 Cause Complex Cerebral Malformations by Disrupting Asymmetrically Dividing Neural Progenitors

35. Copy-Number Disorders Are a Common Cause of Congenital Kidney Malformations

40. Multiple Recurrent De Novo CNVs, Including Duplications of the 7q11.23 Williams Syndrome Region, Are Strongly Associated with Autism

42. De novo TRIM8 variants impair its protein localization to nuclear bodies and cause developmental delay, epilepsy, and focal segmental glomerulosclerosis

47. CAKUT and Autonomic Dysfunction Caused by Acetylcholine Receptor Mutations

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