24 results on '"Obeng, Esther A."'
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2. Splicing factor deficits render hematopoietic stem and progenitor cells sensitive to STAT3 inhibition
3. Preferential expansion of CD8+ CD19-CAR T cells postinfusion and the role of disease burden on outcome in pediatric B-ALL
4. Clones assemble! The clonal complexity of blood during ontogeny and disease
5. The development of therapy related myeloid neoplasms in childhood cancer survivors
6. Congenital macrothrombocytopenia with focal myelofibrosis due to mutations in human G6b-B is rescued in humanized mice
7. 3211 – SF3B1/DNMT3A CO-MUTATIONS MITIGATES DNMT3A PHENOTYPE IN HEMATOPOIETIC STEM AND PROGENITOR CELLS
8. 3138 – EPIGENETIC REGULATORS TET2 AND POLYCOMB REPRESSIVE COMPLEX 2 (PRC2) COORDINATE GENE EXPRESSION IN MYELODYSPLASTIC SYNDROME (MDS)
9. Proteasome inhibitors induce a terminal unfolded protein response in multiple myeloma cells
10. A Murine Model Harboring Cooperating DNMT3A and SF3B1 Mutations Phenocopies SF3B1 Driven Myelodysplastic Syndrome
11. 148 - Venetoclax-Based Combination Therapy As a Bridge to Allogeneic Hematopoietic Stem Cell Transplant in Children with Relapsed/Refractory AML
12. 128 - CD45RA-Depleted Haploidentical Transplantation Combined with NK Cell Addback Results in Promising Long-Term Outcomes in Pediatric Patients with High-Risk Hematologic Malignancies
13. 41 - CD45RA Depleted T-Cell Addback and Prophylactic Blinatumomab Administration Following Tcrαβ/CD19-Depleted Haploidentical Transplantation in Pediatric Patients with High Risk Acute Leukemia
14. 3220 – SF3B1/DNMT3A CO-MUTATION MIMICS FEATURES OF SOLE SF3B1 OR DNMT3A MUTATION DEPENDING ON STRESS CONDITIONS
15. 3137 – A MODIFIED ACTIVIN RECEPTOR TYPE IIB LIGAND TRAP (RAP-536) IMPROVES ANEMIA IN SF3B1K700E MICE BY PROMOTING EARLY-STAGE ERYTHROPOIESIS AND IMPROVING ALTERNATIVE SPLICING
16. 3116 – SELECTIVE TARGETING OF SPLICING FACTOR MUTANT HEMATOPOIETIC STEM AND PROGENITOR CELLS VIA STAT3 INHIBITION
17. 3123 – STAT3 INHIBITION IS A SYNTHETIC LETHAL VULNERABILITY FOR SPLICING FACTOR-MUTATED HEMATOPOIETIC STEM CELLS
18. STAT3 INHIBITION IS A SYNTHETIC LETHAL VULNERABILITY FOR SF3B1-MUTATED HEMATOPOIETIC STEM CELLS
19. Mutant SF3B1 splices a more leukemogenic EVI1
20. 3000 - A Cryptic Intronic GATA1 Splicing Mutation Provides Insights Into Human Hematopoietic Differentiation
21. Congenital Thrombocytopenia and Myelofibrosis Due to Germline Mutations in G6b-B— a Megakaryocyte-Specific Immunoreceptor Tyrosine-Based Inhibitory Motif (ITIM) Receptor
22. Heterozygous Hotspot SF3B1 Mutations Found in Myelodysplastic Syndromes Downregulate Genes Involved in Differentiation of Erythroid Cells
23. Expressionof Sf3b1- K700Ein Murine B Cells Causes Pre-mRNA Splicing and Altered B Cell Differentiation and Function
24. Cancer-Associated Mutations in SF3B1 Exhibit Neomorphic Splicing Activity and Block Erythroid Differentiation
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