49 results on '"Wang, Xunde"'
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2. In vivo measurement of RBC survival in patients with sickle cell disease before or after hematopoietic stem cell transplantation
3. Mitapivat increases ATP and decreases oxidative stress and erythrocyte mitochondria retention in a SCD mouse model
4. The platelet NLRP3 inflammasome is upregulated in sickle cell disease via HMGB1/TLR4 and Bruton tyrosine kinase
5. SENP1, but not fetal hemoglobin, differentiates Andean highlanders with chronic mountain sickness from healthy individuals among Andean highlanders
6. Ligand Activation of ERRα by Cholesterol Mediates Statin and Bisphosphonate Effects
7. A Liver-Bone Endocrine Relay by IGFBP1 Promotes Osteoclastogenesis and Mediates FGF21-Induced Bone Resorption
8. Heme-bound iron activates placenta growth factor in erythroid cells via erythroid Krüppel-like factor
9. HBB rs334, ABO Rs8176703 and Plasmodium Falciparum Positivity at Enrollment Are Independently Associated with Lower Risk for Endemic Burkitt Lymphoma in Uganda, Tanzania, Kenya, and Malawi
10. Pklr Variants Associated with Acute Pain in Sickle Cell Disease Influence ATP Concentrations in Red Blood Cells
11. Genetic variants of PKLR are associated with acute pain in sickle cell disease
12. 14-3-3 Binding and Phosphorylation of Neuroglobin during Hypoxia Modulate Six-to-Five Heme Pocket Coordination and Rate of Nitrite Reduction to Nitric Oxide
13. Human Neuroglobin Functions as a Redox-regulated Nitrite Reductase
14. AMP-activated protein kinase is required for induction of apoptosis and epithelial-to-mesenchymal transition
15. Evaluation of Red Cell Deformability in Sickle Cell Disease Patients, Sickle Cell Carriers, and Healthy Controls Using Lorrca-Derived Parameters
16. Exploring Mitochondrial DNA Heteroplasmy in a Mouse Model of Sickle Cell Disease
17. Copper dependence of the biotin switch assay: Modified assay for measuring cellular and blood nitrosated proteins
18. Hemolysis in sickle cell mice causes pulmonary hypertension due to global impairment in nitric oxide bioavailability
19. Measurement of Nitric Oxide Levels in the Red Cell: VALIDATION OF TRI-IODIDE-BASED CHEMILUMINESCENCE WITH ACID-SULFANILAMIDE PRETREATMENT
20. Lactate dehydrogenase as a biomarker of hemolysis-associated nitric oxide resistance, priapism, leg ulceration, pulmonary hypertension, and death in patients with sickle cell disease
21. Activating Pyruvate Kinase Improves Red Blood Cell Integrity By Reducing Band3 Tyrosine Phosphorylation
22. The Pyruvate Kinase Activator Mitapivat Improves Red Blood Cell Deformability and Sickling Kinetics in Adult Patients with Sickle Cell Disease
23. S-Nitrosohemoglobin Is Unstable in the Reductive Erythrocyte Environment and Lacks O2/NO-linked Allosteric Function
24. Pklr Is a Genetic Modifier of Sickle Cell Disease
25. RNA Seq Profiles and Bioinformatics Validation in a Large Sample of Sickle Cell Disease Patients
26. Platelet Phenotype Prediction from Whole Genome Sequencing in 621 Sickle Cell Disease Patients
27. The NLRP3 Inflammasome in Platelets Is Upregulated in Sickle Cell Disease and Promotes Platelet Aggregation and In Vitro Thrombosis
28. High levels of placenta growth factor in sickle cell disease promote pulmonary hypertension
29. Characterisation of Three Unique Head-to-Tail Alpha Globin Cluster Duplications Contributing to Beta Thalassemia Intermedia in 3 Families
30. Methodological vexation about thiol oxidation versus S-nitrosation—A commentary on “An ascorbate-dependent artifact that interferes with the interpretation of the biotin-switch assay”
31. Erythrocytosis in Chronic Mountain Sickness (CMS) in Andeans
32. Stimulation of Nitric Oxide Synthase Activity By Plasma Apolipoproteins: a Biomarker of Endothelial Function in Adults with Sickle Cell Disease
33. Phase 1 Clinical Trial Of The Candidate Anti-Sickling Agent Aes-103 In Adults With Sickle Cell Anemia
34. The Anti-Sickling Agent Aes-103 Decreases Sickle Erythrocyte Fragility, Hypoxia-Induced Sickling and Hemolysis In Vitro
35. Placenta Growth Factor Is Regulated By Heme-Bound Iron Via Erythroid Krüppel-Like Factor In Erythroid Cells and Is Linked To Iron Status In Vivo In Sickle Cell Disease and Hereditary Hemochromatosis
36. Association of Plasma Cell-Free Hemoglobin with Physiological Measures of Nitric Oxide Responsiveness and Estimated Pulmonary Artery Systolic Pressure: Requirement for Rigorously Optimized Blood Processing Variables
37. Effect of Aes-103 Anti-Sickling Agent On Oxygen Affinity and Stability of Red Blood Cells From Patients with Sickle Cell Anemia
38. Iron Containing Compound Stimulates Expression of Pulmonary Hypertension Promoting Factor PlGF
39. Heme Coordination and Nitrite Reductase Activity of Human Neuroglobin
40. Blood Cell Versus Vascular Endothelial Cell Contributions to Nitrite Homeostasis and Blood Pressure Regulation
41. Eculizumab Reduces Pulmonary Hypertension through Inhibition of Hemolysis-Associated Nitric Oxide Consumption in Patients with Paroxysmal Nocturnal Hemoglobinuria
42. O36. Human neuroglobin functions as an allosteric nitrite reductase in hypoxia
43. Hemolysis in Sickle Cell Mice Causes Pulmonary Hypertension Due to Global Impairment in Nitric Oxide Bioavailability.
44. P165. Ceruloplasmin is an NO oxidase that regulates nitrite homeostasis
45. Lactate Dehydrogenase as a Biomarker of Hemolysis-Associated Nitric Oxide Resistance, Priapism, Leg Ulceration, Pulmonary Hypertension and Death in Patients with Sickle Cell Disease.
46. Mixed Hematopoietic Chimerism for Sickle Cell Disease Prevents Intravascular Hemolysis and Corrects Biomarkers of Endothelial Function.
47. Nitric Oxide Consumption and Pulmonary Hypertension in Patients with Paroxysmal Nocturnal Hemoglobinuria.
48. Spontaneous Pulmonary Hypertension in Transgenic Sickle Cell Mice - Hemodynamics and Histology Suggest Abnormal Nitric Oxide Production and Scavenging.
49. Mixed Chimerism Following Nonmyeloablative Stem Cell Transplantation for Sickle Cell Disease Prevents Intravascular Hemolysis and Restores Endothelial Function.
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