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113 results on '"Cations, Divalent metabolism"'

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1. Two-metal ion mechanism of DNA cleavage by activated, filamentous SgrAI.

2. Free ferrous ions sustain activity of mammalian stearoyl-CoA desaturase-1.

3. Assembly properties of bacterial actin MreB involved in Spiroplasma swimming motility.

4. Binding of calcium and magnesium to human cardiac troponin C.

5. Kinetic and thermodynamic analysis defines roles for two metal ions in DNA polymerase specificity and catalysis.

6. Identification of the ternary complex of ribonuclease HI:RNA/DNA hybrid:metal ions by ESI mass spectrometry.

7. ER stress increases store-operated Ca 2+ entry (SOCE) and augments basal insulin secretion in pancreatic beta cells.

8. Zinc transporter 10 (ZnT10)-dependent extrusion of cellular Mn 2+ is driven by an active Ca 2+ -coupled exchange.

9. Co(II) and Ni(II) binding of the Escherichia coli transcriptional repressor RcnR orders its N terminus, alters helix dynamics, and reduces DNA affinity.

10. Different Divalent Cations Alter the Kinetics and Fidelity of DNA Polymerases.

11. Amidase Activity of AmiC Controls Cell Separation and Stem Peptide Release and Is Enhanced by NlpD in Neisseria gonorrhoeae.

12. Computation and Functional Studies Provide a Model for the Structure of the Zinc Transporter hZIP4.

13. Negatively charged amino acids near and in transient receptor potential (TRP) domain of TRPM4 channel are one determinant of its Ca2+ sensitivity.

14. Substrate inhibition of uracil phosphoribosyltransferase by uracil can account for the uracil growth sensitivity of Leishmania donovani pyrimidine auxotrophs.

15. Pink1 kinase and its membrane potential (Deltaψ)-dependent cleavage product both localize to outer mitochondrial membrane by unique targeting mode.

16. Activation of mitochondrial calcium-independent phospholipase A2γ (iPLA2γ) by divalent cations mediating arachidonate release and production of downstream eicosanoids.

17. Structural and mechanistic implications of metal binding in the small heat-shock protein αB-crystallin.

18. Divalent cation transport by vesicular nucleotide transporter.

19. Interactions of cations with the cytoplasmic pores of inward rectifier K(+) channels in the closed state.

20. Baculovirus envelope protein ODV-E66 is a novel chondroitinase with distinct substrate specificity.

21. Cu(II) mediates kinetically distinct, non-amyloidogenic aggregation of amyloid-beta peptides.

22. A single zinc ion is sufficient for an active Trypanosoma brucei tRNA editing deaminase.

23. 2E8 binds to the high affinity I-domain in a metal ion-dependent manner: a second generation monoclonal antibody selectively targeting activated LFA-1.

24. Disease variants of the human mitochondrial DNA helicase encoded by C10orf2 differentially alter protein stability, nucleotide hydrolysis, and helicase activity.

25. Specific Inhibition of NEIL-initiated repair of oxidized base damage in human genome by copper and iron: potential etiological linkage to neurodegenerative diseases.

26. Structural insights into the catalytic mechanism of bacterial guanosine-diphospho-D-mannose pyrophosphorylase and its regulation by divalent ions.

27. Insights into regulated ligand binding sites from the structure of ZO-1 Src homology 3-guanylate kinase module.

28. Her4 and Her2/neu tyrosine kinase domains dimerize and activate in a reconstituted in vitro system.

29. Calcium is essential for the major pseudopilin in the type 2 secretion system.

30. Substrate recognition of anthrax lethal factor examined by combinatorial and pre-steady-state kinetic approaches.

31. Cyclopiazonic acid is complexed to a divalent metal ion when bound to the sarcoplasmic reticulum Ca2+-ATPase.

32. Identification of pore residues engaged in determining divalent cationic permeation in transient receptor potential melastatin subtype channel 2.

33. Dictyostelium myosin-5b is a conditional processive motor.

34. FE(II) is the native cofactor for Escherichia coli methionine aminopeptidase.

35. Metal ion substrate inhibition of ferrochelatase.

36. Proton conductivity through the human TRPM7 channel and its molecular determinants.

37. Essential role of the N-terminal domain in the regulation of RIG-I ATPase activity.

38. Deconvoluting the Cu2+ binding modes of full-length prion protein.

39. NRAMP-1 expression modulates protein-tyrosine phosphatase activity in macrophages: impact on host cell signaling and functions.

40. Evolution of differences in transport function in Slc11a family members.

41. The metalloreductase Fre6p in Fe-efflux from the yeast vacuole.

42. In vitro modeling of matrix vesicle nucleation: synergistic stimulation of mineral formation by annexin A5 and phosphatidylserine.

43. Molecular determinants of Mg2+ and Ca2+ permeability and pH sensitivity in TRPM6 and TRPM7.

44. The N-terminal arm of the Helicobacter pylori Ni2+-dependent transcription factor NikR is required for specific DNA binding.

45. Calcium inhibition and calcium potentiation of Orai1, Orai2, and Orai3 calcium release-activated calcium channels.

46. Neutralization of acidic residues in helix II stabilizes the folded conformation of acyl carrier protein and variably alters its function with different enzymes.

47. A small molecule agonist of an integrin, alphaLbeta2.

48. Structural snapshots of Escherichia coli histidinol phosphate phosphatase along the reaction pathway.

49. Ca2+ and Mg2+ binding properties of GCAP-1. Evidence that Mg2+-bound form is the physiological activator of photoreceptor guanylyl cyclase.

50. Binding and transport of metal ions at the dimer interface of the Escherichia coli metal transporter YiiP.

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