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Your search keyword '"Bulat, Zorica"' showing total 26 results
Start Over Author "Bulat, Zorica" Publisher elsevier ireland ltd, clare
26 results on '"Bulat, Zorica"'

1. Cadmium as oxidative stress inducer in brain of subacutely exposed rats and its implication on zinc level

Author

Bulat, Zorica, Bulat, Zorica, Ćurčić, Marijana, Antunović, Marko, Vučinić, Slavica, Buha-Đorđević, Aleksandra, Janković, Saša, Nikolić, Dragica, Matović, Vesna, Đukić-Ćosić, Danijela, Antonijević, Evica, Baralić, Katarina, Antonijević, Biljana, Bulat, Zorica, Bulat, Zorica, Ćurčić, Marijana, Antunović, Marko, Vučinić, Slavica, Buha-Đorđević, Aleksandra, Janković, Saša, Nikolić, Dragica, Matović, Vesna, Đukić-Ćosić, Danijela, Antonijević, Evica, Baralić, Katarina, and Antonijević, Biljana

Published
2017

2. Effect assessment of target tissue doses of cadmium and decabrominated diphenyl ether on GSH level in kidneys

Author

Ćurčić, Marijana, Ćurčić, Marijana, Buha-Đorđević, Aleksandra, Milovanović, V., Janković, Saša, Vučinić, Slavica, Antonijević, Evica, Đukić-Ćosić, Danijela, Bulat, Zorica, Matović, Vesna, Antonijević, Biljana, Ćurčić, Marijana, Ćurčić, Marijana, Buha-Đorđević, Aleksandra, Milovanović, V., Janković, Saša, Vučinić, Slavica, Antonijević, Evica, Đukić-Ćosić, Danijela, Bulat, Zorica, Matović, Vesna, and Antonijević, Biljana

Published
2018

3. Toxicogenomics analysis of phthalates and bisphenol A mixture: Obesity and comorbidities

Author

Baralić, Katarina, Baralić, Katarina, Jorgovanović, D., Matović, Vesna, Antonijević, Biljana, Bulat, Zorica, Ćurčić, Marijana, Antonijević, Evica, Đukić-Ćosić, Danijela, Baralić, Katarina, Baralić, Katarina, Jorgovanović, D., Matović, Vesna, Antonijević, Biljana, Bulat, Zorica, Ćurčić, Marijana, Antonijević, Evica, and Đukić-Ćosić, Danijela

Published
2018

8. Interactions between cadmium and decabrominated diphenyl ether on blood cells count in rats-Multiple factorial regression analysis

Author

Ćurčić, Marijana, Ćurčić, Marijana, Buha, Aleksandra, Stanković, Sanja, Milovanović, Vesna, Bulat, Zorica, Đukić-Ćosić, Danijela, Antonijević, Evica, Vucnić, Slavica, Matović, Vesna, Antonijević, Biljana, Ćurčić, Marijana, Ćurčić, Marijana, Buha, Aleksandra, Stanković, Sanja, Milovanović, Vesna, Bulat, Zorica, Đukić-Ćosić, Danijela, Antonijević, Evica, Vucnić, Slavica, Matović, Vesna, and Antonijević, Biljana

Abstract

The objective of this study was to assess toxicity of Cd and BDE-209 mixture on haematological parameters in subacutely exposed rats and to determine the presence and type of interactions between these two chemicals using multiple factorial regression analysis. Furthermore, for the assessment of interaction type, an isobologram based methodology was applied and compared with multiple factorial regression analysis. Chemicals were given by oral gavage to the male Wistar rats weighing 200-240g for 28 days. Animals were divided in 16 groups (8/group): control vehiculum group, three groups of rats were treated with 2.5, 7.5 or 15 mg Cd/kg/day. These doses were chosen on the bases of literature data and reflect relatively high Cd environmental exposure, three groups of rats were treated with 1000, 2000 or 4000 mg BDE-209/kg/bw/day, doses proved to induce toxic effects in rats. Furthermore, nine groups of animals were treated with different mixtures of Cd and BDE-209 containing doses of Cd and BDE-209 stated above. Blood samples were taken at the end of experiment and red blood cells, white blood cells and platelets counts were determined. For interaction assessment multiple factorial regression analysis and fitted isobologram approach were used. In this study, we focused on multiple factorial regression analysis as a method for interaction assessment. We also investigated the interactions between Cd and BDE-209 by the derived model for the description of the obtained fitted isobologram curves. Current study indicated that co-exposure to Cd and BDE-209 can result in significant decrease in RBC count, increase in WBC count and decrease in PLT count, when compared with controls. Multiple factorial regression analysis used for the assessment of interactions type between Cd and BDE-209 indicated synergism for the effect on RBC count and no interactions i.e. additivity for the effects on WBC and PLT counts. On the other hand, isobologram based approach showed slight antagonism

Published
2017

9. Obesity in relation with erythrocyte lead level in people exposed to environmental lead in Belgrade, Serbia

Author

Baralić, Katarina, Baralić, Katarina, Ćurčić, Marijana, Antonijević, Evica, Bulat, Zorica, Janković, Saša, Todorović, Milica, Milosavljević, Filip, Kotur-Stevuljević, Jelena, Kalimanovska, Vesna, Matović, Vesna, Antonijević, Biljana, Đukić-Ćosić, Danijela, Baralić, Katarina, Baralić, Katarina, Ćurčić, Marijana, Antonijević, Evica, Bulat, Zorica, Janković, Saša, Todorović, Milica, Milosavljević, Filip, Kotur-Stevuljević, Jelena, Kalimanovska, Vesna, Matović, Vesna, Antonijević, Biljana, and Đukić-Ćosić, Danijela

Published
2017

12. Assessment of mercury intake via fish and fish products among children in Belgrade, Serbia: A pilot study

Author

Đukić-Ćosić, Danijela, Đukić-Ćosić, Danijela, Antonijević, Evica, Ćurčić, Marijana, Lazarević, L., Jorgovanović, D., Vidosavljević, M., Janković, Saša, Bulat, Zorica, Buha, Aleksandra, Matović, Vesna, Antonijević, Biljana, Đukić-Ćosić, Danijela, Đukić-Ćosić, Danijela, Antonijević, Evica, Ćurčić, Marijana, Lazarević, L., Jorgovanović, D., Vidosavljević, M., Janković, Saša, Bulat, Zorica, Buha, Aleksandra, Matović, Vesna, and Antonijević, Biljana

Published
2016

14. Influence of decabrominated diphenyl ether on oxidative stress in brain caused by cadmium

Author

Ćurčić, Marijana, Ćurčić, Marijana, Buha, Aleksandra, Milovanović, V., Antunović, M., Đorđević, S., Vučinić, Slavica, Đukić-Ćosić, Danijela, Bulat, Zorica, Matović, Vesna, Antonijević, Biljana, Ćurčić, Marijana, Ćurčić, Marijana, Buha, Aleksandra, Milovanović, V., Antunović, M., Đorđević, S., Vučinić, Slavica, Đukić-Ćosić, Danijela, Bulat, Zorica, Matović, Vesna, and Antonijević, Biljana

Published
2016

16. Risk assessment of mercury intake via marine food among pregnant women in Serbia: Deterministic and probabilistic approaches

Author

Đukić-Ćosić, Danijela, Đukić-Ćosić, Danijela, Antonijević, Evica, Ćurčić, Marijana, Bulat, Zorica, Vidosavljević, M., Lazarević, L., Janković, Saša, Matović, Vesna, Antonijević, Biljana, Đukić-Ćosić, Danijela, Đukić-Ćosić, Danijela, Antonijević, Evica, Ćurčić, Marijana, Bulat, Zorica, Vidosavljević, M., Lazarević, L., Janković, Saša, Matović, Vesna, and Antonijević, Biljana

Published
2015

20. The impact of prolonged cadmium exposure and co-exposure with polychlorinated biphenyls on thyroid function in rats

Author

Buha, Aleksandra, Buha, Aleksandra, Antonijević, Biljana, Bulat, Zorica, Jaćević, Vesna, Milovanović, Vesna, Matović, Vesna, Buha, Aleksandra, Buha, Aleksandra, Antonijević, Biljana, Bulat, Zorica, Jaćević, Vesna, Milovanović, Vesna, and Matović, Vesna

Abstract

Endocrine-disrupting chemicals currently represent one of the major concerns and this study was aimed to investigate the effects of different doses of cadmium, widespread toxic metal, on the levels of thyroid hormones and to calculate Benchmark doses for these effects. Furthermore, the effects of co-exposure to cadmium and polychlorinated biphenyls on thyroid function were investigated. Six orally-treated groups of rats were receiving 0.3, 0.6, 1.25, 2.5, 5 and 10 mg Cd/kg b.w./day, five groups were orally treated with 0.5, 1, 2, 4 and 8 mg PCBs/kgb.w./day, while nine groups of rats were orally-treated with different dose combinations of Cd and PCBs (0.6, 1.25 and 2.5 mg Cd/kgb.w. and 2,4 and 8 mg PCBs/kg b.w./day), during 28 days. Thyroid hormones were adversely affected by cadmium, with most prominent effect observed on triiodothyroxine levels indicating Cd interference with thyroid function at extrathyroidal level. Calculated Benchmark doses for Cd effects on thyroid hormones indicate triiodothyroxine as the most sensitive one that can be used as a basis for risk assessment. This study also implicates possible synergistic effects of Cd and PCBs on thyroid function as a consequence of their interference at different levels of thyroid homeostasis.

Published
2013

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