42 results on '"Cucchiarini, M"'
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2. Biomaterial-assisted gene therapy for translational approaches to treat musculoskeletal disorders
3. Macroscopic cartilage repair scoring of defect fill, integration and total points correlate with corresponding items in histological scoring systems – a study in adult sheep
4. Advances in combining gene therapy with cell and tissue engineering-based approaches to enhance healing of the meniscus
5. Loss of spatial organization and destruction of the pericellular matrix in early osteoarthritis in vivo and in a novel in vitro methodology
6. 2D and 3D MOCART scoring systems assessed by 9.4 T high-field MRI correlate with elementary and complex histological scoring systems in a translational model of osteochondral repair
7. PTH [1-34]-induced alterations of the subchondral bone provoke early osteoarthritis
8. Temporal and spatial migration pattern of the subchondral bone plate in a rabbit osteochondral defect model
9. Experimental scoring systems for macroscopic articular cartilage repair correlate with the MOCART score assessed by a high-field MRI at 9.4 T – comparative evaluation of five macroscopic scoring systems in a large animal cartilage defect model
10. Raav-Mediated Fgf-2 And TGF-β Overexpression Via Alginate Hydrogel Delivery Stimulates The Reparative Abilities Of Human Meniscal Lesions In Situ
11. Stimulation Of The Chondroreparative Activities Of Human Osteoarthritic Articular Chondrocytes Upon Overexpression Of Sox9 And Tgf-Β Via Raav Gene Vector Delivery In An Alginate-Based Hydrogel
12. Subchondral Bone Changes In Osteoarthritis Animal Models And Humans Induced By Meniscal Lesions - A Systematic Review Of The Literature
13. Carbon dot-guided delivery of therapeutic (SOX9, TGF-β) rAAV vectors to enhance the biological activity of human articular chondrocytes
14. Genetically modified human bone marrow aspirates by rAAV mediated overexpression of sox9 and TGF-beta viapnass-grafted poly(e-caprolactone) film-guided delivery activates the chondrogenic activity upon implantation in human osteochondral defects
15. Benefits of photopolymerizable hydrogels for the effective delivery of raav vectors in human bone marrow derived mesenchymal stem cells
16. Chondrogenic differentiation of human bone marrow aspirates enhanced by overexpression of RAAV- SOX9 and TGF-B upon vector delivery via pnass-grafted microstructured poly(E-caprolactone) scaffolds
17. Effects of raav-mediated overexpression of SOX9 and TGF-β via carbon dots on the chondrogenesis of human bone marrow-derived mesenchymal stem cells
18. Overexpression of bone morphogenetic protein 3 (BMP-3) via raav-mediated gene transfer on the osteochondrogenic fate of human bone marrow-derived mesenchymal stem cells
19. Effective genetic modification of human bone marrow-derived mesenchymal stem cells upon control delivery of raav vectors via carbon dot nanocarriers
20. Carbon dots nanocarriers for the effective rAAV mediated transduction of human osteoarthritic chondrocytes in vitro
21. Overexpression of rAAV-SOX9 and TGF-B in human bone marrow aspirates upon vector delivery via pNaSS-coated poly(e-caprolactone) scaffolds
22. rAAV mediated combined gene transfer and overexpression of TGF-beta and IGF-I in human bone marrow-derived mesenchymal stem cells upon implantation in a human osteochondral defect model
23. Chondrogenic differentiation processes in human bone marrow-derived mesenchymal stem cells upon raav mediated co-overexpression of TGF-B and IGF-I
24. Dual FGF-2 and SOX9 gene transfer via RAAV Vectors: effects on the chondrogenic and metabolic processes in human bone marrow aspirates
25. rAAV SOX9 gene transfer stimulates the chondrogenic differentiation activities in human peripheral blood aspirates
26. PEO-PPO-PEO micelles as effective rAAV-mediated delivery systems to overexpress SOX9 in human osteoarthritic articular chondrocytes
27. Genetic modification of human bone marrow aspirates via delivery of rAAV vectors coated on pNaSS-grafted poly(ε-caprolactone) scaffolds
28. Genome editing for human osteoarthritis – a perspective
29. Recombinant adeno associated virus mediated cooverexpression of transforming growth factor beta and SOX9 genes enhance the metabolic and chondrogenic activities in human bone marrow aspirates
30. Co-overexpression of TGF-β and SOX9 via rAAV gene transfer modulates the metabolic and chondrogenic activities of human bone marrow-derived mesenchymal stem cells
31. RAAV-mediated combined gene transfer and overexpression of TGF-β and SOX9 remodels human osteoarthritic articular cartilage
32. Axial knee alignment influences the repair of focal articular cartilage defects – A translational study in sheep
33. Effects of exosomes upon the metabolic activities of human osteoarthritic articular cartilage in situ
34. Enhanced chondrogenic differentiation of human osteoarthritic bone marrow aspirates modified to overexpress the transcription factor sox9 via rAAV-mediated gene transfer in dynamic versus static culture conditions
35. Effects of IGF-I overexpression on the chondrogenic potential of human bone marrow aspirates modified via rAAV gene transfer
36. The survival of motor neuron (SMN) protein: a new factor of the progression of osteoarthritis
37. Alterations of the subchondral bone induced by PTH [1-34] provoke early osteoarthritis in vivo
38. 525 EXPANSION AND CHONDROGENIC DIFFERENTIATION OF HUMAN BONE MARROW-DERIVED MESENCHYMAL STEM CELLS FOLLOWING RAAV-MEDIATED GENE TRANSFER AND OVEREXPRESSION OF HUMAN FGF-2
39. 165 DIRECT RAAV-MEDIATED IGF-I OVEREXPRESSION ENHANCES ARTICULAR CARTILAGE REPAIR IN VIVO
40. P178 Transplanted allogenic chondrocytes simultaneously overexpressing human insulin-like growth factor I (IGF-I) and fibroblast growth factor-2 (FGF-2) stimulate articular cartilage repair in vivo
41. P29 Biochemical, immunohistochemical and histological evaluation of the cartilaginous tissue resulting from marrow-stimulating techniques
42. 9.3 Co-overexpression via rAAV of human S0X9 and FGF-2 enhances the repair of articular cartilage defects in vivo
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