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Your search keyword '"Dion RL"' showing total 6 results
Start Over Author "Dion RL" Publisher elsevier science
6 results on '"Dion RL"'

1. Mechanism of resistance to the oncolytic C-nucleoside 2-beta-D-ribofuranosylthiazole-4-carboxamide (NSC-286193).

Author

Jayaram HN, Cooney DA, Glazer RI, Dion RL, and Johns DG

Subjects
Animals, Antineoplastic Agents metabolism, Drug Resistance, Guanosine Triphosphate metabolism, Leukemia P388 metabolism, Mice, Neoplasm Transplantation, Ribavirin analogs & derivatives, Ribavirin metabolism, Time Factors, Antineoplastic Agents pharmacology, Leukemia P388 drug therapy, Leukemia, Experimental drug therapy, Ribavirin pharmacology, Ribonucleosides pharmacology
Published
1982
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2. Initial studies on the mechanism of action of a new oncolytic thiazole nucleoside, 2-beta-D-ribofuranosylthiazole-4-carboxamide (NSC 286193).

Author

Jayaram HN, Dion RL, Glazer RI, Johns DG, Robins RK, Srivastava PC, and Cooney DA

Subjects
Animals, Cell Division drug effects, Cell Survival drug effects, DNA, Neoplasm biosynthesis, Hypoxanthines metabolism, IMP Dehydrogenase metabolism, Leukemia L1210 drug therapy, Leukemia P388 drug therapy, Ligases metabolism, Mice, Ribavirin analogs & derivatives, Structure-Activity Relationship, Antineoplastic Agents pharmacology, Carbon-Nitrogen Ligases, Ribavirin pharmacology, Ribonucleosides pharmacology
Published
1982
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3. Conversion of 2-beta-D-ribofuranosylselenazole-4-carboxamide to an analogue of NAD with potent IMP dehydrogenase-inhibitory properties.

Author

Jayaram HN, Ahluwalia GS, Dion RL, Gebeyehu G, Marquez VE, Kelley JA, Robins RK, Cooney DA, and Johns DG

Subjects
Animals, Gas Chromatography-Mass Spectrometry, Mice, Selenium chemical synthesis, IMP Dehydrogenase antagonists & inhibitors, Ketone Oxidoreductases antagonists & inhibitors, Leukemia P388 drug therapy, Leukemia, Experimental drug therapy, NAD analogs & derivatives, Organoselenium Compounds, Ribavirin analogs & derivatives, Ribavirin toxicity, Ribonucleosides chemical synthesis, Ribonucleosides toxicity, Selenium toxicity
Published
1983
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5. Surface alterations of P388 leukemia cells by 2-deoxy-D-glucose.

Author

Myers-Robfogel MW, Canellakis ZN, Bono VH Jr, Dion RL, Cunningham LS, and Sartorelli AC

Subjects
Animals, Cell Aggregation drug effects, Cell Cycle, Cell Membrane drug effects, Cell Membrane metabolism, Cell Membrane ultrastructure, DNA, Neoplasm metabolism, Deoxyglucose metabolism, Galactosyltransferases metabolism, In Vitro Techniques, Lectins metabolism, Lectins pharmacology, Leukemia, Experimental metabolism, Mice, Sialyltransferases metabolism, Deoxy Sugars pharmacology, Deoxyglucose pharmacology, Leukemia, Experimental ultrastructure
Published
1979
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6. Maleimide--biochemical, pharmacologic and toxicologic studies. Interaction with L-asparagine metabolism.

Author

Cooney DA, Milman HA, Cable RG, Dion RL, and Bono VH Jr

Subjects
Acid Phosphatase metabolism, Amylases metabolism, Animals, Asparaginase metabolism, Aspartate-Ammonia Ligase metabolism, Drug Interactions, Glutamine metabolism, In Vitro Techniques, L-Lactate Dehydrogenase metabolism, Maleimides toxicity, Mice, Mice, Inbred Strains, Microsomes, Liver metabolism, Nucleic Acids metabolism, Proteins metabolism, Transaminases metabolism, Asparagine metabolism, Maleimides pharmacology
Published
1978
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