1. The Longitudinal Evolution of Post-COVID-19 Outcomes Among Hemodialysis Patients in Turkey
- Author
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Savas Ozturk, Kenan Turgutalp, Mustafa Arici, Numan Gorgulu, Halil Zeki Tonbul, Necmi Eren, Vedat Gencer, Mehmet Deniz Ayli, Irem Pembegul, Murside Esra Dolarslan, Zeynep Ural, Hulya Colak, Tuba Elif Ozler, Ozgur Can, Mehmet Emin Demir, Orcun Altunoren, Bulent Huddam, Kursad Onec, Bulent Demirelli, Zeki Aydin, Eda Altun, Selma Alagoz, Yavuz Ayar, Zeynep Ebru Eser, Bayram Berktas, Zulfukar Yilmaz, Eser Uslu Ates, Enver Yuksel, Gizem Kumru Sahin, Merve Aktar, Egemen Cebeci, Belda Dursun, Sibel Yucel Kocak, Abdulmecit Yildiz, Sinan Kazan, Mahmut Gok, Erkan Sengul, Murat Tugcu, Ramazan Ozturk, Serdar Kahvecioglu, Ekrem Kara, Bulent Kaya, Garip Sahin, Tamer Sakaci, Savas Sipahi, Ilhan Kurultak, Beyza Algul Durak, Mehmet Riza Altiparmak, Sabahat Alisir Ecder, Serhat Karadag, Mevlut Tamer Dincer, Hakan Ozer, Sibel Gokcay Bek, Memnune Sena Ulu, Ozkan Gungor, Elif Ari Bakir, Ali Riza Odabas, Nurhan Seyahi, Alaattin Yildiz, Kenan Ates, Pembegül, İrem, MÜ, Tıp Fakültesi, Dahili Tıp Bilimleri Bölümü, Huddam, Bülent, RTEÜ, Tıp Fakültesi, Dahili Tıp Bilimleri Bölümü, and Kara, Ekrem
- Subjects
Mortality-Rates ,hemodialysis ,Nephrology ,Hemodialysis ,Nationwide study ,outcome ,COVID-19 ,OVID-19 ,nationwide study ,Transplant ,Outcome - Abstract
Introduction: Hemodialysis (HD) patients have increased risk for short-term adverse outcomes of COVID-19. However, complications and survival at the post-COVID-19 period have not been published extensively.Methods: We conducted a national, multicenter observational study that included adult maintenance HD patients recovered from confirmed COVID-19. A control HD group without COVID-19 was selected from patients in the same center. We investigated the characteristics and outcomes in the follow-up of HD patients and compare them with the non-COVID-19 group.Results: A total of 1223 patients (635 patients in COVID-19 group, 588 patients in non-COVID-19 group) from 47 centers were included in the study. The patients' baseline and HD characteristics were almost similar. The 28th-day mortality and mortality between 28th day and 90th day were higher in the COVID-19 group than non-COVID-19 group (19 [3.0%] patients vs. none [0%]; 15 [2.4%] patients vs. 4 [0.7%] patients, respectively). The presence of respiratory symptoms, rehospitalization, need for home oxygen therapy, lower respiratory tract infection, and arteriovenous (AV) fistula thrombosis was significantly higher in the COVID-19 group in both the first 28 days and between 28 and 90 days. In the multivariable analysis, age (odds ratio [OR] [95% CI]: 1.029 [1.004-1.056]), group (COVID-19 group vs. non-COVID-19 group) (OR [95% CI]: 7.258 [2.538-20.751]), and vascular access type (tunneled catheter/AV fistula) (OR [95% CI]: 2.512 [1.249-5.051]) were found as independent parameters related to 90-day mortality.Conclusion: In the post-COVID-19 period, maintenance HD patients who have had COVID-19 have increased rehospitalization, respiratory problems, vascular access problems, and high mortality compared with the non-COVID-19 HD patients.
- Published
- 2022