1. Analysis of the Intrahospital and Long-Term Survival of Heart Transplant Patients With a Short-Term Mechanical Assistance Device
- Author
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Azucena Pajares Moncho, Raquel López-Vilella, Ricardo Gimeno Costa, Ignacio Sánchez-Lázaro, Mónica Talavera Peregrina, Luis Martínez Dolz, Iratxe Zarragoikoetxea Jáuregui, Manuel Pérez Guillén, Luis Almenar Bonet, Víctor Donoso Trenado, and Salvador Torregrosa Puerta
- Subjects
Heart Failure ,Heart transplantation ,Transplantation ,medicine.medical_specialty ,business.industry ,medicine.medical_treatment ,Mechanical assistance ,Surgery ,Extracorporeal Membrane Oxygenation ,Treatment Outcome ,surgical procedures, operative ,Ventricular assist device ,Long term survival ,Circulatory system ,medicine ,Extracorporeal membrane oxygenation ,Heart Transplantation ,Humans ,Transplant patient ,Heart-Assist Devices ,Child ,business ,Retrospective Studies - Abstract
BACKGROUND The purpose of this study was to compare early and late survival among patients who have undergone heart transplantation (HTx) with a short-term mechanical assist device. METHODS This was an ambispective, single-center, consecutive study of patients undergoing urgent HTx for 5 years. Pediatric transplants, retransplants, and combined transplants were excluded. Forty-five patients were included. Four groups were analyzed: those with venoarterial extracorporeal membrane oxygenation (ECMO) implanted 10 days; patients classified as INTERMACS 2 to 3 with Levitronix Centrimag implanted; and those classified as INTERMACS 2 with Levitronix Centrimag implanted. Survival and the influence of orotracheal intubation (OI) at the time of transplantation were compared. RESULTS There were differences in in-hospital mortality (P = .03) and total mortality (P = .06). The groups with the highest risk for mortality were those who carried ECMO for >10 days before transplantation or those classified as INTERMACS 2 with Levitronix Centrimag implanted. In these groups, the need for posttransplant circulatory support was also greater (P = .04) as was the length of stay in critical care (P = .02). The need for OI during the days of care and until transplantation had a negative effect on survival in all groups (P < .1). CONCLUSIONS There are different risk subgroups among patients who are transplanted with a circulatory/ventricular assist device. The lowest mortality occurs when the days of ECMO implantation are
- Published
- 2021