1. Adherence in Diabetes Questionnaire (ADQ) score as predictor of 11-year HbA 1c trajectories in children and adolescents with type 1 diabetes: A population-based longitudinal study.
- Author
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Marks KP, Birkebæk NH, Pouwer F, Ibfelt EH, Thastum M, and Jensen MB
- Subjects
- Humans, Adolescent, Child, Longitudinal Studies, Glycated Hemoglobin, Surveys and Questionnaires, Registries, Diabetes Mellitus, Type 1 diagnosis
- Abstract
Aims: To identify 11-year HbA
1c trajectories in children/adolescents with type 1 diabetes and determine whether baseline caregiver- and/or child/adolescent-reported Adherence in Diabetes Questionnaire (ADQ) scores and multiple covariates predict HbA1c trajectory membership., Methods: For a 2009 population-based cohort of children/adolescents with type 1 diabetes, we analyzed HbA1c follow-up (2010-2020) data from Danish diabetes registries. HbA1c trajectories were identified with group-based trajectory modeling. Using multinomial logistic regression, we tested whether ADQ scores predicted trajectory membership when adjusting for sex, age at diabetes diagnosis, diabetes duration, family structure, and caregiver education., Results: For 671 children/adolescents (10-17 years at baseline) with 5644 HbA1c observations over 11 years, four trajectories/groups were identified: 1) "on target, gradual decrease" (27%), 2) "above target, mild increase then decrease" (39%), 3) "above target, moderate increase then decrease" (25%), and 4) "well above target, large increase then decrease" (9%). Using group one as the reference, lower caregiver-reported ADQ scores predicted group 2, 3, and 4 membership. Lower child/adolescent-reported ADQ scores predicted group 3 and 4 membership. Low caregiver education predicted group 3 and 4 membership. Single-parent status predicted group 4 membership., Conclusions: ADQ scores and socio-demographics may serve as tools to predict glycemic control in youth with type 1 diabetes., Competing Interests: Declaration of Competing Interest The authors declare that they have no known competing financial interests or personal relationships that could have appeared to influence the work reported in this paper., (Copyright © 2023 The Author(s). Published by Elsevier B.V. All rights reserved.)- Published
- 2023
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