Search

Your search keyword '"Yuval Nevo"' showing total 2 results
Start Over Author "Yuval Nevo" Publisher embo
2 results on '"Yuval Nevo"'

2. Single‐cell transcriptomics reveals a senescence‐associated <scp>IL</scp> ‐6/ <scp>CCR6</scp> axis driving radiodermatitis

Author

Mor Paldor, Orr Levkovitch‐Siany, Dana Eidelshtein, Revital Adar, Claes D Enk, Yitzhak Marmary, Sharona Elgavish, Yuval Nevo, Hadar Benyamini, Inbar Plaschkes, Shiri Klein, Alex Mali, Stefan Rose‐John, Amnon Peled, Eithan Galun, and Jonathan H Axelrod

Subjects
Receptors, CCR6, Mice, Interleukin-6, Interleukin-17, Animals, Molecular Medicine, Radiodermatitis, Transcriptome
Abstract

Irradiation-induced alopecia and dermatitis (IRIAD) are two of the most visually recognized complications of radiotherapy, of which the molecular and cellular basis remains largely unclear. By combining scRNA-seq analysis of whole skin-derived irradiated cells with genetic ablation and molecular inhibition studies, we show that senescence-associated IL-6 and IL-1 signaling, together with IL-17 upregulation and CCR6

Published
2022

Catalog

Books, media, physical & digital resources
See catalog results