1. Evaluation of non-exudative microcystoid macular abnormalities secondary to retinal vein occlusion
- Author
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Kouros Nouri-Mahdavi, Juliet Essilfie, Jean-Pierre Hubschman, David Sarraf, Lisa Yun, Anibal Francone, and Andrea Govetto
- Subjects
Aging ,Visual acuity ,genetic structures ,Branch retinal vein occlusion ,Microcystoid macular abnormalities ,Visual Acuity ,Glaucoma ,Angiogenesis Inhibitors ,Optic neuropathy ,Neurodegenerative ,Eye ,Ophthalmology & Optometry ,Retinal vein occlusion ,0302 clinical medicine ,Central retinal vein occlusion ,Occlusion ,Medicine ,Tomography ,Inner nuclear layer ,Sensory Systems ,Treatment Outcome ,Intravitreal Injections ,Retinal Disorders ,medicine.symptom ,Tomography, Optical Coherence ,medicine.medical_specialty ,Retinal Vein ,Macular Edema ,Retina ,03 medical and health sciences ,Cellular and Molecular Neuroscience ,Opthalmology and Optometry ,Ophthalmology ,Humans ,Microcystoid macular changes ,Eye Disease and Disorders of Vision ,Optical coherence tomography ,business.industry ,Neurosciences ,medicine.disease ,eye diseases ,Microcystoid degeneration ,Optical Coherence ,Concomitant ,Microcysts ,030221 ophthalmology & optometry ,sense organs ,business ,030217 neurology & neurosurgery ,Follow-Up Studies - Abstract
Purpose We aimed to investigate non-exudative microcystoid macular abnormalities for visual and anatomical outcome in patients with retinal vein occlusion (RVO) with and without glaucomatous optic neuropathy (GON). Methods Medical records of 124 eyes (105 patients) with RVO were reviewed and analyzed. Eyes demonstrating microcystoid macular abnormalities were divided into 2 groups, those with evidence of glaucoma (group A) and those without glaucoma (group B). Best-corrected visual acuity (BCVA), the prevalence and number of microcystoid macular abnormalities, and number of intravitreal anti-vascular endothelial growth factor (anti-VEGF) injections were compared at baseline and follow-up. Results Seventy-one out of 105 eyes (67.6%) with RVO displayed microcystoid macular abnormalities. Thirty-eight out of 71 eyes (53.5%) presented with concomitant glaucoma (group A), while the remaining 33 eyes (42.6%) had no history of glaucoma (group B). At the end of the follow-up period, mean BCVA was worse in group A versus group B (20/80 versus 20/40, respectively; p = .003). The mean number of anti-VEGF injections was 10.1 ± 9.2 in group A versus 5.9 ± 6.9 in group B (p = .03). Conclusion Eyes with RVO and concomitant glaucoma exhibited a significantly higher number of microcystoid macular abnormalities and worse BCVA versus eyes with RVO without glaucoma.
- Published
- 2021