1. Gender, TIMI risk score and in-hospital mortality in STEMI patients undergoing primary PCI: results from the Belgian STEMI registry
- Author
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Marc J. Claeys, Philippe Dubois, Christophe Beauloye, Jean Boland, Marc Renard, Sofie Gevaert, Carl Convens, Pascal Vranckx, Herbert De Raedt, Antoine De Meester, Els Vandecasteele, Patrick Evrard, Dirk De Bacquer, Patrick Coussement, and Peter Sinnaeve
- Subjects
Adult ,Male ,Risk ,medicine.medical_specialty ,medicine.medical_treatment ,Myocardial Infarction ,Logistic regression ,Sex Factors ,Internal medicine ,medicine ,Humans ,Hospital Mortality ,Prospective Studies ,Registries ,cardiovascular diseases ,Myocardial infarction ,Angioplasty, Balloon, Coronary ,Prospective cohort study ,Aged ,Aged, 80 and over ,Framingham Risk Score ,business.industry ,Mortality rate ,Age Factors ,Percutaneous coronary intervention ,Middle Aged ,Prognosis ,medicine.disease ,Treatment Outcome ,surgical procedures, operative ,Conventional PCI ,Physical therapy ,Female ,Cardiology and Cardiovascular Medicine ,business ,TIMI - Abstract
Aims: The relationship between the predictive performance of the TIMI risk score for STEMI and gender has not been evaluated in the setting of primary PCI (pPCI). Here, we compared in-hospital mortality and predictive performance of the TIMI risk score between Belgian women and men undergoing pPCI. Methods and results: In-hospital mortality was analysed in 8,073 (1,920 [23.8%] female and 6,153 [76.2%] male patients) consecutive pPCI-treated STEMI patients, included in the prospective, observational Belgian STEMI registry (January 2007 to February 2011). A multivariable logistic regression model, including TIMI risk score variables and gender, evaluated differences in in-hospital mortality between men and women. The predictive performance of the TIMI risk score according to gender was evaluated in terms of discrimination and calibration. Mortality rates for TIMI scores in women and men were compared. Female patients were older, had more comorbidities and longer ischaemic times. Crude in-hospital mortality was 10.1% in women vs. 4.9% in men (OR 2.2; 95% CI: 1.82-2.66, p
- Published
- 2014