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BACKGROUND: The aim of this study is to compare the possible functional involvement of the vestibulo-ocular reflex in the follicular and luteal phases. METHODS: The research was carried out at a university located in eastern Turkey. The study included 37 healthy female volunteering students aged 18-25 years. The functional head impulse test was applied twice in the follicular phase and in the luteal phase, and the results in both phases were compared. RESULTS: In the functional head impulse test, statistically significant differences were obtained between the follicular phase and the luteal phase at the stimulus to the lateral semicircular canal direction total and 6000°/s² acceleration percentage of correct answers values, the posterior semicircular canal direction stimulations at 3000°/s² and 5000°/s² acceleration percentage of correct answers values, and the anterior semicircular canal direction stimulations at 5000°/s² acceleration percentage of correct answers values. CONCLUSION: In the luteal phase, which corresponds to the period before menstruation, the vestibulo-ocular reflex is functionally negatively affected. [ABSTRACT FROM AUTHOR]