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OBJECTIVE: To investigate the characteristics of occurrence of adverse drug reactions(ADR) in Wuxi the Eighth People’s Hospital(hereinafter referred to as "our hospital"),so as to provide reference for clinical rational drug application. METHODS: 169 cases of ADR reports collected in our hospital in 2017 were retrospectively analyzed in terms of patients’ genders,ages, drug application, involved organs and(or) systems, clinical manifestations, etc. RESULTS: Of the 169 ADR reports, 149(88.2%) were general ADR cases; 85 cases were male, 84 cases were male; patients aged ≥60 had taken the largest proportion(79 cases, 46.7%). 71 categories of drugs were involved, mainly were antibiotics(75 cases, 44.4%); the ADR-inducing administration route was mainly intravenous drip(121 cases, 71.6%); of the clinical manifestations of ADR, damages in skin and its accessories were the most common. CONCLUSIONS: The occurrence of ADR are related to various factors,hospitals should strengthen "medical-medicine-nursing" co-operation in ADR monitoring, give full play to the role of clinical pharmacists in medication monitoring to ensure rational drug application and reduce or avoid ADR. [ABSTRACT FROM AUTHOR]

OBJECTIVE: To investigate the characteristics of occurrence of adverse drug reactions (ADR) in Wuxi the Eighth People's Hospital (hereinafter referred to as “our hospital”), so as to provide reference for the clinical rational drug use. METHODS: 155 cases of ADR reported to the National ADR Center by our hospital in 2015 were collected, analysis was conducted on patients'gender, age, administration, involving organs and (or) systems, and clinical manifestations, etc. RESULTS: Of the 155 ADR reports, there were more males than females, the number of patients aged ≤10 and >60 years old took the lead, respectively 58 cases (37. 42%) and 66 cases (42. 58%). A total of 8 kinds of drugs were involved, including 50 categories, among which anti-infective drugs dominated the first place (79 cases, 50. 97%). ADR mainly involved organs and (or) systems (77 cases, 47. 24%). The clinical symptoms were performed as skin rash, pruritus and irritation, etc. The most common ADR were induced by intravenous infusion(118 cases, 76. 13%). CONCLUSIONS: The occurrence of ADR are related to various factors, the hospital should strengthen medical, medicine and nursing co-operation in ADR monitoring, minimize the intravenous routes and reduce or avoid the occurrence of ADR, so as to promote the rational drug use in clinic. [ABSTRACT FROM AUTHOR]