1. Severe clinical spectrum with high mortality in pediatric patients with COVID-19 and multisystem inflammatory syndrome
- Author
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Magda Carneiro-Sampaio, Karine Vusberg Galleti, Heloisa Helena de Sousa Marques, Maria de Fátima Rodrigues Diniz, Nadia Litvinov, Adriana Pasmanik Eisencraft, João Renato Rebello Pinho, Camila Sanson Yoshino de Paula, Claudio Schvartsman, Vinicius Rodrigues Fernandes, Ester Cerdeira Sabino, Sylvia Costa Lima Farhat, Juliana Valéria de Souza Framil, Anarella Penha Meirelles de Andrade, Alfioâ Rossi Junior, Maria Fernanda Badue Pereira, Mussya Cisotto Rocha, Giovanna Gavros Palandri, Patricia Palmeira Daenekas Jorge, Maria Augusta Bento Cicaroni Gibelli, Thelma Suely Okay, Clovis A. Silva, Gabriela Nunes Leal, Andreia Watanabe, Maria Fernanda Mota Fonseca, Artur Figueiredo Delgado, Kelly Aparecida Kanunfre, Werther Brunow de Carvalho, Alice Lima Fante, and Thais de Toledo Fink
- Subjects
Male ,Medicine (General) ,medicine.medical_treatment ,030204 cardiovascular system & hematology ,Severity of Illness Index ,Gastroenterology ,Hypoxemia ,Outcome, Immunosuppression ,0302 clinical medicine ,Oxygen therapy ,030212 general & internal medicine ,Child ,Children ,Pediatric intensive care unit ,Univariate analysis ,Mortality rate ,Immunoglobulins, Intravenous ,General Medicine ,Systemic Inflammatory Response Syndrome ,Original Article ,medicine.symptom ,Coronavirus Infections ,Diarrhea ,medicine.medical_specialty ,Fever ,Adolescent ,Vomiting ,Multisystem Inflammatory Syndrome ,Pneumonia, Viral ,Mucocutaneous Lymph Node Syndrome ,Betacoronavirus ,03 medical and health sciences ,R5-920 ,Internal medicine ,medicine ,Humans ,Renal replacement therapy ,Glucocorticoids ,Pandemics ,SARS-CoV-2 ,business.industry ,COVID-19 ,Odds ratio ,medicine.disease ,Respiration, Artificial ,Abdominal Pain ,Coronavirus ,Systemic inflammatory response syndrome ,Cross-Sectional Studies ,business - Abstract
OBJECTIVES: To assess the outcomes of pediatric patients with laboratory-confirmed coronavirus disease (COVID-19) with or without multisystem inflammatory syndrome in children (MIS-C). METHODS: This cross-sectional study included 471 samples collected from 371 patients (age50 mg/L (83% vs. 25%, p=0.008) and D-dimer levels >1000 ng/mL (100% vs. 40%, p=0.007) and the median D-dimer, troponin T, and ferritin levels (p
- Published
- 2020