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Your search keyword '"Viviane Cunha Cardoso"' showing total 7 results
Start Over Author "Viviane Cunha Cardoso" Publisher federacao brasileira das sociedades de ginecologia e obstetricia
7 results on '"Viviane Cunha Cardoso"'

1. Mid-pregnancy circulating cytokine levels, placental efficiency and their relationship with preterm birth

Author

Carlos Grandi, Karina Bezerra Salomão, Stella Felippe de Freitas, Paulo Ricardo Higassiaraguti Rocha, Ricardo de Carvalho Cavalli, and Viviane Cunha Cardoso

Subjects
Cytokines, Preterm birth, Pregnancy, Placenta, Gynecology and obstetrics, RG1-991
Abstract

Abstract Objective To assess a panel of cytokines and placental insufficiency with the risk of preterm delivery (PTD). Methods Nested case-control study into the BRISA birth cohort. Eighty-two mother-infant-placenta pairs were selected at 20+0 to 25+6 weeks. Circulating biomarker levels were performed using Luminex flowmetric xMAP technology. Cytokines classified as Th1, Th2 or Th17 and other biomarkers were selected. The ratio between birth weight and placental weight (BW/PW) was used as a proxy for placental efficiency. Spearman correlation, univariate analyses and logistic regression models were calculated. Sensitivity, specificity, positive and negative likelihood ratios were calculated using the Receiver Operating Characteristic curve. Results Mean gestational age was 250 days, 14,6% were small for gestational age, 4,8% large for gestational age and 13,4% stunted. Placental efficiency was higher for term newborns (p

Published
2024
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2. Sociodemographic and reproductive risk factors associated with metabolic syndrome in a population of Brazilian women from the city of Ribeirão Preto: a cross-sectional study

Author

Ênio Luis Damaso, Heloisa Bettiol, Viviane Cunha Cardoso, Mariane Nunes de Nadai, Elaine Christine Dantas Moisés, Carolina Sales Vieira, and Ricardo Carvalho Cavalli

Subjects
Obesity, Metabolic syndrome, Cohort study, Risk factors, Gynecology and obstetrics, RG1-991
Abstract

Abstract Objective: To identify sociodemographic and reproductive risk factors associated with MetS in women in their fourth decade of life. Methods: Cohort study conducted on women born from June 1978 to May 1979 in Ribeirão Preto, Brazil. Sociodemographic, clinical, and obstetric data were collected by interview and clinical evaluation. Univariable and multivariable binomial logistic regression models were constructed to identify the risk factors of metabolic syndrome and the adjusted relative risk (RR) was calculated. Results: The cohort included 916 women, and 286 (31.2%) of them have metabolic syndrome. MetS was associated with lack of paid work (RR 1.49; 95% CI 1.14-1.95), marital status of without a partner (RR 1.33; 95% CI 1.03-1.72), low educational level (less than 8 years of schooling [RR 1.72; 95% CI 1.23-2.41], 8 to 12 years of schooling [RR 1.37; 95% CI 1.06-1.76], when compared with more than 12 years of schooling), and teenage pregnancy (RR 2.00; 95% CI 1.45-2.77). There was no association between MetS, and the other covariates studied. Conclusion: Metabolic syndrome in a population of women in the fourth decade of life was associated with lack of employment, lack of a partner, low educational level, and teenage pregnancy.

Published
2024
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3. Prediction of Perinatal and Neurodevelopmental Outcomes in Newborns with a Birth Weight below the 3rd Percentile: Performance of Two International Curves – Prospective Cohort from a Brazilian City

Author

Marcos Masaru Okido, Ricardo de Carvalho Cavalli, Viviane Cunha Cardoso, and Alessandra Cristina Marcolin

Subjects
fetal growth retardation, birth weight, neurodevelopmental disorders, Gynecology and obstetrics, RG1-991
Abstract

Abstract Objectives To evaluate the performance of Intergrowth-21 st (INT) and Fetal Medicine Foundation (FMF) curves in predicting perinatal and neurodevelopmental outcomes in newborns weighing below the 3rd percentile. Methods Pregnant women with a single fetus aged less than 20 weeks from a general population in non-hospital health units were included. Their children were evaluated at birth and in the second or third years of life. Newborns (NB) had their weight percentiles calculated for both curves. Sensitivity, specificity, positive (PPV) and negative predictive value (NPV), and area under the ROC curve (ROC-AUC) for perinatal outcomes and neurodevelopmental delay were calculated using birth weight < 3rd percentile as the cutoff. Results A total of 967 children were evaluated. Gestational age at birth was 39.3 (± 3.6) weeks and birth weight was 3,215.0 (± 588.0) g. INT and FMF classified 19 (2.4%) and 49 (5.7%) newborns below the 3rd percentile, respectively. The prevalence of preterm birth, tracheal intubation >24 hours in the first three months of life, 5th minute Apgar

Published
2023
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4. Association between Caffeine Consumption in Pregnancy and Low Birth Weight and Preterm Birth in the birth Cohort of Ribeirão Preto

Author

Fernanda Pino Vitti, Carlos Grandi, Ricardo de Carvalho Cavalli, Vanda Maria Ferreira Simões, Rosângela Fernandes Lucena Batista, and Viviane Cunha Cardoso

Subjects
caffeine, pregnancy, cohort studies, low birth weight, preterm birth, Gynecology and obstetrics, RG1-991
Abstract

Abstract Objective To describe caffeine consumption during pregnancy and its association with low birth weight (LBW) and preterm birth in the birth cohort of Ribeirão Preto, state of São Paulo, Brazil, in 2010. Methods Cohort study, with descriptive and analytical approach. Data included 7,607 women and their newborns in Ribeirão Preto, state of São Paulo, Brazil. The women answered standardized questionnaires about reproductive health, prenatal care, life habits, sociodemographic conditions, and information about coffee intake. The independent variable was high caffeine consumption (≥300 mg/day) from coffee during pregnancy, and the dependent variables were LBW (birth weight < 2,500 g) and preterm birth (< 37 weeks of gestational age). Four adjusted polytomous logistic regression models, relative risk (RR) and 95% confidence interval (CI) were fitted: biological and sociodemographic conditions; obstetric history; current gestational conditions; and all variables included in the previous models. Results A total of 4,908 (64.5%) mothers consumed caffeine, 143 (2.9%) of whom reported high consumption. High caffeine intake was significantly associated with reduced education and with the occupation of the head of the family, nonwhite skin color, not having a partner, higher parity, previous abortion and preterm birth, urinary tract infection, threatened abortion, alcohol consumption and smoking. No association was found between high caffeine consumption and LBW or preterm birth in both Conclusion In this cohort, high caffeine intake was lower than in other studies and no association with LBW or preterm birth was found.

Published
2018
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5. Circulating Tissue Inhibitor of Metalloproteinase-4 levels are not a Predictor of Preeclampsia in the period between 20 and 25 Weeks of Gestation

Author

Valeria Cristina Sandrim, Jackeline Machado, Heloisa Bettiol, Marco Antonio Barbieri, Viviane Cunha Cardoso, Ana Carolina Palei, and Ricardo Carvalho Cavalli

Subjects
preeclampsia, TIMP-4, TIMPs, MMPs, prediction, circulating biomarkers, angiogenic biomarkers, Gynecology and obstetrics, RG1-991
Abstract

Abstract Objective To evaluate whether the circulating level of tissue inhibitor of metalloproteinase- 4 (TIMP-4) in the period between 20 and 25 weeks of gestation is a predictor of preeclampsia. Methods We have performed a case-control study, nested in a prospective study cohort in Ribeirão Preto, in the state of São Paulo, Brazil. Of the 1,400 pregnant women evaluated between 20 and 25 weeks of gestation, 460 delivered in hospitals outside of our institution. Of the 940 pregnant women who completed the protocol, 30 developed preeclampsia. Healthy pregnant women (controls, n = 90) were randomly selected from the remaining 910 participants. From blood samples collected between 20 and 25 weeks of gestation, we performed a screening of 55 angiogenesis-related proteins in 4 cases and 4 controls. The protein TIMP-4 was the most differentially expressed between cases and controls. Therefore, wemeasured this protein in all cases (n = 30) and controls selected (n = 90). Results There were no differences in the plasma TIMP-4 levels of cases compared with controls (1,144 263 versus 1,160 362 pg/mL, respectively; p > 0.05). Conclusion Plasma TIMP-4 levels were not altered at 20 to 25 weeks of gestation, before the manifestation of clinical symptoms; therefore, they are not good predictors of the development of preeclampsia.

Published
2018
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6. Circulating Tissue Inhibitor of Metalloproteinase-4 levels are not a Predictor of Preeclampsia in the period between 20 and 25 Weeks of Gestation

Author

Marco Antonio Barbieri, Valeria C. Sandrim, Jackeline de Souza Rangel Machado, Ana C. Palei, Heloisa Bettiol, Ricardo de Carvalho Cavalli, Viviane Cunha Cardoso, Universidade Estadual Paulista (Unesp), Universidade de São Paulo (USP), and Univ Mississippi

Subjects
Adult, medicine.medical_specialty, TIMPs, 030204 cardiovascular system & hematology, Preeclampsia, preeclampsia, 03 medical and health sciences, 0302 clinical medicine, Pre-Eclampsia, Predictive Value of Tests, Pregnancy, Medicine, Humans, Prospective cohort study, TIMP-4, 030219 obstetrics & reproductive medicine, business.industry, Obstetrics, angiogenic biomarkers, Case-control study, Obstetrics and Gynecology, circulating biomarkers, Tissue Inhibitor of Metalloproteinases, Gynecology and obstetrics, prediction, Tissue inhibitor of metalloproteinase, medicine.disease, METALOPROTEINASES, Predictive value of tests, Case-Control Studies, Pregnancy Trimester, Second, Cohort, RG1-991, Gestation, Female, MMPs, business
Abstract

Made available in DSpace on 2019-10-04T18:35:41Z (GMT). No. of bitstreams: 0 Previous issue date: 2018-12-01. Added 1 bitstream(s) on 2019-10-09T18:34:30Z : No. of bitstreams: 1 S0100-72032018001200757.pdf: 930727 bytes, checksum: 2dcd425f3f3bff914d7553da4493d489 (MD5) Fundação de Amparo à Pesquisa do Estado de São Paulo (FAPESP) Conselho Nacional de Desenvolvimento Científico e Tecnológico (CNPq) Objective To evaluate whether the circulating level of tissue inhibitor of metalloproteinase-4 (TIMP-4) in the period between 20 and 25 weeks of gestation is a predictor of preeclampsia. Methods We have performed a case-control study, nested in a prospective study cohort in Ribeirao Preto, in the state of Sao Paulo, Brazil. Of the 1,400 pregnant women evaluated between 20 and 25 weeks of gestation, 460 delivered in hospitals outside of our institution. Of the 940 pregnant women who completed the protocol, 30 developed preeclampsia. Healthy pregnant women (controls, n = 90) were randomly selected from the remaining 910 participants. From blood samples collected between 20 and 25 weeks of gestation, we performed a screening of 55 angiogenesis-related proteins in 4 cases and 4 controls. The protein TIMP-4 was the most differentially expressed between cases and controls. Therefore, we measured this protein in all cases (n = 30) and controls selected (n = 90). Results There were no differences in the plasma TIMP-4 levels of cases compared with controls (1,144 +/- 263 versus 1,160 +/- 362 pg/mL, respectively; p > 0.05). Conclusion Plasma TIMP-4 levels were not altered at 20 to 25 weeks of gestation, before the manifestation of clinical symptoms; therefore, they are not good predictors of the development of preeclampsia. Univ Estadual Paulista, Dist Rubiao Jr S-N, BR-18618000 Botucatu, SP, Brazil Univ Sao Paulo, Ribeirao Preto, SP, Brazil Univ Mississippi, Med Ctr, Jackson, MS 39216 USA Univ Estadual Paulista, Dist Rubiao Jr S-N, BR-18618000 Botucatu, SP, Brazil FAPESP: 2015/20461-8 FAPESP: 2008/53593-0 CNPq: 2014-5/305587

Published
2018

7. Medidas de crescimento placentário em relação ao peso de nascimento em uma população latino-americana

Author

Carlos Grandi, Nancy Mazzitelli, Ricardo de Carvalho Cavalli, Viviane Cunha Cardoso, and Angélica Veiga

Subjects
Adult, medicine.medical_specialty, Pediatrics, Adolescent, Birth weight, Placenta, Population, 010501 environmental sciences, placental characteristics, 01 natural sciences, Young Adult, 03 medical and health sciences, 0302 clinical medicine, peso da placenta, Pregnancy, peso ao nascer, Humans, Medicine, 030212 general & internal medicine, características da placenta, education, gestational age, Retrospective Studies, 0105 earth and related environmental sciences, Fetus, education.field_of_study, business.industry, Obstetrics, Singleton, Obstetrics and Gynecology, Gestational age, birth weight, Retrospective cohort study, Organ Size, Gynecology and obstetrics, Middle Aged, medicine.disease, Placentation, Latin America, medicine.anatomical_structure, RG1-991, Female, business, placental weight, idade gestacional
Abstract

Introduction The placenta, translates how the fetus experiences the maternal environment and is a principal influence on birth weight (BW). Objective To explore the relationship between placental growth measures (PGMs) and BW in a public maternity hospital. Methods Observational retrospective study of 870 singleton live born infants at Hospital Maternidad Sardá, Universidad de Buenos Aires, Argentina, between January 2011 and August 2012 with complete data of PGMs. Details of history, clinical and obstetrical maternal data, labor and delivery and neonatal outcome data, including placental measures derived from the records, were evaluated. The following manual measurements of the placenta according to standard methods were performed: placental weight (PW, g), larger and smaller diameters (cm), eccentricity, width (cm), shape, area (cm2), BW/PW ratio (BPR) and PW/BW ratio (PBR), and efficiency. Associations between BW and PGMs were examined using multiple linear regression. Results Birth weight was correlated with placental weight (R2 =0.49, p < 0.001), whereas gestational age was moderately correlated with placental weight (R2 =0.64, p < 0.001). By gestational age, there was a positive trend for PW and BPR, but an inverse relationship with PBR (p < 0.001). Placental weight alone accounted for 49% of birth weight variability (p < 0,001), whereas all PGMs accounted for 52% (p < 0,001). Combined, PGMs, maternal characteristics (parity, pre-eclampsia, tobacco use), gestational age and gender explained 77.8% of BW variations (p < 0,001). Among preterm births, 59% of BW variances were accounted for by PGMs, compared with 44% at term. All placental measures except BPR were consistently higher in females than in males, which was also not significant. Indices of placental efficiency showed weakly clinical relevance. Conclusions Reliable measures of placental growth estimate 53.6% of BW variances and project this outcome to a greater degree in preterm births than at term. These findings would contribute to the understanding of the maternal-placental programming of chronic diseases. Resumo Introdução Aplacenta traduz como o feto experimenta o ambientematerno, alémde ser a principal influência sobre o peso ao nascer (PN). Objetivo Explorar a relação entre medidas de crescimento da placenta (MCPs) e PN em uma maternidade pública. Métodos Estudo retrospectivo observacional de 870 recém-nascidos vivos únicos na Maternidade Sardá, Universidade de Buenos Aires, Argentina, entre janeiro de 2011 e agosto de 2012 com os dados completos das MCPs. Foram avaliados dados da história clínica e obstétricamaterna, trabalho de parto e resultados neonatais, incluindomedidas da placenta derivadas dos registrosmédicos. Foramrealizadas as seguintesmediçõesmanuais da placenta: peso da placenta (PP, g), diâmetros maior e menor (cm), excentricidade, espessura (cm), forma, área (cm2), razões PN/PP e PP/PN e eficiência. Associações entre PN e MCPs foram examinadas por meio de regressão linear múltipla. Resultados Peso ao nascer foi correlacionado com peso placentário (R2 = 0,49, p < 0,001), enquanto idade gestacional foi moderadamente correlacionada com peso placentário (R2 = 0,64, p < 0,001). Por idade gestacional, houve uma tendência positiva para a relação PP e PN/PP, mas uma relação inversa com a razão PP/PN (p < 0,001). Somente peso da placenta respondeu por 49% da variabilidade do peso ao nascer (p < 0,001), ao passo que todas as MCPs foram responsáveis por 52% (p < 0,001). Combinados, MCPs, características maternas (paridade, pré-eclâmpsia, fumo), idade gestacional e sexo explicaram 77,8% da variação do peso ao nascer (p < 0,001). Entre nascimentos pré-termo, 59% da variância do PN foi contabilizada pelas MCPs, emcomparação com44% a termo. Todas asmedidas placentárias, exceto a razão PN/PP, foram consistentemente maiores em mulheres do que em homens, mas não significativas. Índices de eficiência placentária mostraram fraca relevância clínica. Conclusões medidas confiáveis de crescimento placentário estimam 53,6% da variância do peso ao nascer, e projetamesse resultado a ummaior grau emnascimentos pré-termo do que a termo. Estes resultados contribuiriam para a compreensão da programação materno-placentária de doenças crónicas.

Published
2016

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