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Positive correlation between starting bacterial density and raw optical density of positive control. A positive correlation was noted between the starting bacterial density values obtained at 600Â nm and the raw optical density values of the positive control wells. P and rho values were obtained using the Spearmanâ s correlation test. (PDF 18Â kb)

NMDS ordination plot for seven CF subjects at two clinic visits (paired analysis). Principal coordinate analysis by non-metric multidimensional scaling generated from Bray-Curtis dissimilarity matrices at the genus level from seven CF subjects at two clinic visits. P value was obtained using HOMOVA. No separation was noted between the paired samples. (PDF 139Â kb)

Diversity and richness of CF microbiome in subjects at two clinic visits (paired analysis). Panels show uncensored number of genera, inverse Simpson index, Chao1 index, Shannon diversity Index. P values were generated using Wilcoxon matched-pairs signed-rank tests. No significant differences were noted between clinic visits. (PDF 17Â kb)

Oxidative activity of sputum samples from seven CF subjects at two clinic visits (paired analysis). Group well color density of metabolic activity corrected for starting bacterial density. P values were generated using Wilcoxon matched-pairs signed-rank tests. No significant differences were noted between clinic visits. (PDF 21Â kb)

Oxidative activity of sputum samples from seven CF subjects at two clinic visits (paired analysis). Group well color density of metabolic activity corrected for starting bacterial density. P values were generated using Wilcoxon matched-pairs signed-rank tests. No significant differences were noted between clinic visits. (PDF 21Â kb)