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Table S1. Composition of diets. (DOCX 109 kb)

Figure S1. Changes in blood glucose and insulin sensitivity in mice fed with LFD or LFD + B. a Weekly changes in blood glucose levels over 4–16 weeks. b Insulin tolerance test (ITT) was performed in 16-week-old mice and blood glucose levels were assessed at the indicated times following an intraperitoneal injection of insulin (0.5 U/kg body weight). Values were represented as the percent of t = 0 glucose levels. n = 4–8 mice per group. (PDF 35 kb)

The primers used in the paper. (DOCX 14 kb)

Predicted targets of OsmiR159 by psRobot and their expressions detected by RNAseq. (DOCX 15 kb)

Phylogenetic analysis of the targets of OsmiR159 and AtmiR159. (DOCX 54 kb)

Summary of small RNA classes in the samples. Table S2. Expression abundance of the known miRNAs. Table S3. Regions of the target genes identified by degradome sequencing. Table S4. Primers used in miRNA and target gene validation. (DOCX 61 kb)

Expression levels of all RNA-seq libraries. The boxplot of CPM normalized expression for all 24 libraries. (PDF 6Â kb)