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1. Additional file 1 of Fatigue in young adults with juvenile idiopathic arthritis 18 years after disease onset: data from the prospective Nordic JIA cohort

Author

Arnstad, Ellen Dalen, Glerup, Mia, Rypdal, Veronika, Peltoniemi, Suvi, Fasth, Anders, Nielsen, Susan, Zak, Marek, Aalto, Kristiina, Berntson, Lillemor, Nordal, Ellen, Herlin, Troels, Romundstad, Pål Richard, and Marite Rygg

Abstract

Additional file 1: Figure S1. The distribution of fatigue scores at the 18-year follow-up of participants with juvenile idiopathic arthritis (JIA) in the Nordic JIA study and in the Norwegian control group. Fatigue is measured with Fatigue Severity Scale (FSS) global score, 1–7 (1 = lowest, 7 = highest). The dot-plot illustrating the distribution of fatigue scores for individual participants within each group as dots, and the group median indicated with the horizontal spiked line.

Published
2021
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5. Additional file 1 of Pain sensitivity in young adults with juvenile idiopathic arthritis: a quantitative sensory testing study

Author

Arnstad, Ellen Dalen, Iversen, Johanne Marie, Uglem, Martin, Glerup, Mia, Romundstad, Pål Richard, Sand, Trond, and Marite Rygg

Subjects
musculoskeletal diseases, genetic structures, immune system diseases, skin and connective tissue diseases
Abstract

Additional file 1: Supplementary Table S1. Thermal detection thresholds among juvenile idiopathic arthritis (JIA) and controls.

Published
2020
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6. MOESM3 of Validation of prediction models of severe disease course and non-achievement of remission in juvenile idiopathic arthritis: part 1—results of the Canadian model in the Nordic cohort

Author

Rypdal, Veronika, Guzman, Jaime, Henrey, Andrew, Loughin, Thomas, Glerup, Mia, Arnstad, Ellen, Aalto, Kristiina, Marite Rygg, Nielsen, Susan, Herlin, Troels, Fasth, Anders, Berntson, Lillemor, Rypdal, Martin, and Nordal, Ellen

Abstract

Additional file 3: Figure S2. Receiver operating characteristic (ROC) curve showing the result of the univariate logistic regression model with cumulative active joint count as the predictor variable and severe disease course as the outcome. C-index of 0.85 (IQR 0.82–0.88).

Published
2019
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8. MOESM1 of Validation of prediction models of severe disease course and non-achievement of remission in juvenile idiopathic arthritis: part 1â€'results of the Canadian model in the Nordic cohort

Author

Rypdal, Veronika, Guzman, Jaime, Henrey, Andrew, Loughin, Thomas, Glerup, Mia, Arnstad, Ellen, Aalto, Kristiina, Marite Rygg, Nielsen, Susan, Herlin, Troels, Fasth, Anders, Berntson, Lillemor, Rypdal, Martin, and Nordal, Ellen

Abstract

Additional file 1: Table S1. Characteristics of the four clusters identified in the Nordic JIA cohort. Cluster 3 and 4 correspond to the severe disease course outcome defined in the ReACCh-Out cohort.

Published
2019
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9. MOESM2 of Validation of prediction models of severe disease course and non-achievement of remission in juvenile idiopathic arthritis: part 1â€'results of the Canadian model in the Nordic cohort

Author

Rypdal, Veronika, Guzman, Jaime, Henrey, Andrew, Loughin, Thomas, Glerup, Mia, Arnstad, Ellen, Aalto, Kristiina, Marite Rygg, Nielsen, Susan, Herlin, Troels, Fasth, Anders, Berntson, Lillemor, Rypdal, Martin, and Nordal, Ellen

Abstract

Additional file 2: Figure S1. Calibration curves for the Canadian model in the Nordic JIA cohort. Each point represents one tenth of the patient sample, arranged from lowest to highest probability of the outcome. A: For predicting severe disease course. B: For predicting non-achievement of remission.

Published
2019
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11. MOESM2 of Oral health in children and adolescents with juvenile idiopathic arthritis – a systematic review and meta-analysis

Author

Skeie, Marit, Gil, Elisabeth, Cetrelli, Lena, Rosén, Annika, Fischer, Johannes, Åstrøm, Anne, Luukko, Keijo, Xieqi Shi, Feuerherm, Astrid, Abhijit Sen, Frid, Paula, Marite Rygg, and Bletsa, Athanasia

Abstract

Additional file 2: Table S2. Scale adapted after Newcastle-Ottawa Quality Assessment Scale for cross-sectional studies by Herzog et al. [75] and further modified in support of this systematic review

Published
2019
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12. MOESM2 of Complement lectin pathway protein levels reflect disease activity in juvenile idiopathic arthritis: a longitudinal study of the Nordic JIA cohort

Author

Glerup, Mia, Thiel, Steffen, Rypdal, Veronika, Arnstad, Ellen, Ekelund, Maria, Peltoniemi, Suvi, Aalto, Kristiina, Marite Rygg, Nielsen, Susan, Fasth, Anders, Berntson, Lillemor, Nordal, Ellen, and Herlin, Troels

Subjects
musculoskeletal diseases, genetic structures, immune system diseases, skin and connective tissue diseases, eye diseases
Abstract

Additional file 2: Table S2. Clinical characteristics of participants in the Nordic JIA cohort at the 17-year follow-up visit. y* = mean in years ± SD, ANA = antinuclear antibodies, HLA-B27 = human leucocyte antigen B27, CRP = C-Reactive Protein, ESR = Erythrocyte Sedimentation Rate, IQR = 1st-3rd interquartile range, JADAS71 = juvenile arthritis disease activity score of 71 joints, sJIA = systemic JIA, Oligo persist = oligo persistent JIA, Oligo ext. = oligo extended JIA, Poly RF- = polyarticular rheumatoid factor negative JIA, Poly RF+ = polyarticular rheumatoid factor positive JIA, ERA = enthesitis-related arthritis, Undiff = undifferentiated JIA. (DOCX 17 kb)

Published
2019
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13. MOESM1 of Complement lectin pathway protein levels reflect disease activity in juvenile idiopathic arthritis: a longitudinal study of the Nordic JIA cohort

Author

Glerup, Mia, Thiel, Steffen, Rypdal, Veronika, Arnstad, Ellen, Ekelund, Maria, Peltoniemi, Suvi, Aalto, Kristiina, Marite Rygg, Nielsen, Susan, Fasth, Anders, Berntson, Lillemor, Nordal, Ellen, and Herlin, Troels

Subjects
musculoskeletal diseases, genetic structures, immune system diseases, skin and connective tissue diseases
Abstract

Additional file 1: Table S1. Clinical characteristics of participants in the Nordic JIA cohort at baseline. y* = mean in years ±SD,** = active joint count at the visit 6 months after onset (− 1/+ 2 months), *** = cumulative joint count during the first 6 months (− 1/+ 2 months) after disease onset, ****DMARDs = Disease modifying anti-rheumatic drugs at the baseline visit, ANA = antinuclear antibodies, HLA-B27 = human leucocyte antigen B27, CRP = C-Reactive Protein, ESR = Erythrocyte Sedimentation Rate, IQR = 1st-3rd interquartile range, JADAS71 = juvenile arthritis disease activity score of 71 joints, sJIA = systemic JIA, Oligo persist = oligo persistent JIA, Oligo ext. = oligo extended JIA, Poly RF- = polyarticular rheumatoid factor negative JIA, Poly RF+ = polyarticular rheumatoid factor positive JIA, ERA = enthesitis-related arthritis, Undiff = undifferentiated JIA. (DOCX 17 kb)

Published
2019
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15. Additional file 3: of Predicting unfavorable long-term outcome in juvenile idiopathic arthritis: results from the Nordic cohort study

Author

Rypdal, Veronika, Arnstad, Ellen, Aalto, Kristiina, Berntson, Lillemor, Ekelund, Maria, Fasth, Anders, Glerup, Mia, Herlin, Troels, Nielsen, Susan, Peltoniemi, Suvi, Zak, Marek, Marite Rygg, Rypdal, Martin, and Nordal, Ellen

Abstract

Figure S1. Receiver operating characteristic (ROC) curves for the four unfavorable clinical outcomes in the validation sets, but for models constructed without using blood samples as predictors. The colored lines are the mean ROC curves for the 100 different realizations of the partitioning of the cohort into training sets and validation sets (thin gray curves). (a) Not in remission. (b) Childhood Health Assessment Questionnaire (CHAQ) >0. (c) Physical Summary Score (PhS)â 0. (PDF 435 kb)

Published
2018
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16. Additional file 6: of Predicting unfavorable long-term outcome in juvenile idiopathic arthritis: results from the Nordic cohort study

Author

Rypdal, Veronika, Arnstad, Ellen, Aalto, Kristiina, Berntson, Lillemor, Ekelund, Maria, Fasth, Anders, Glerup, Mia, Herlin, Troels, Nielsen, Susan, Peltoniemi, Suvi, Zak, Marek, Marite Rygg, Rypdal, Martin, and Nordal, Ellen

Subjects
body regions, nervous system, fungi
Abstract

Table S5. Baseline clinical characteristics as predictors of joint damage (JADI-A) in univariate logistic regression. (PDF 161 kb)

Published
2018
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17. Additional file 2: of Predicting unfavorable long-term outcome in juvenile idiopathic arthritis: results from the Nordic cohort study

Author

Rypdal, Veronika, Arnstad, Ellen, Aalto, Kristiina, Berntson, Lillemor, Ekelund, Maria, Fasth, Anders, Glerup, Mia, Herlin, Troels, Nielsen, Susan, Peltoniemi, Suvi, Zak, Marek, Marite Rygg, Rypdal, Martin, and Nordal, Ellen

Subjects
body regions, nervous system, fungi
Abstract

Table S2. Medications given before the baseline study visit. (PDF 108 kb)

Published
2018
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18. Additional file 3: of Predicting unfavorable long-term outcome in juvenile idiopathic arthritis: results from the Nordic cohort study

Author

Rypdal, Veronika, Arnstad, Ellen, Aalto, Kristiina, Berntson, Lillemor, Ekelund, Maria, Fasth, Anders, Glerup, Mia, Herlin, Troels, Nielsen, Susan, Peltoniemi, Suvi, Zak, Marek, Marite Rygg, Rypdal, Martin, and Nordal, Ellen

Abstract

Figure S1. Receiver operating characteristic (ROC) curves for the four unfavorable clinical outcomes in the validation sets, but for models constructed without using blood samples as predictors. The colored lines are the mean ROC curves for the 100 different realizations of the partitioning of the cohort into training sets and validation sets (thin gray curves). (a) Not in remission. (b) Childhood Health Assessment Questionnaire (CHAQ) >0. (c) Physical Summary Score (PhS)â 0. (PDF 435 kb)

Published
2018
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19. Additional file 7: of Predicting unfavorable long-term outcome in juvenile idiopathic arthritis: results from the Nordic cohort study

Author

Rypdal, Veronika, Arnstad, Ellen, Aalto, Kristiina, Berntson, Lillemor, Ekelund, Maria, Fasth, Anders, Glerup, Mia, Herlin, Troels, Nielsen, Susan, Peltoniemi, Suvi, Zak, Marek, Marite Rygg, Rypdal, Martin, and Nordal, Ellen

Abstract

Figure S2. Receiver operating characteristic (ROC) curves for a test in the Nordic JIA cohort of the prediction model for severe disease course by Guzman et al. The area under the curve (AUC) values were 0.69 for non-achievement of remission off medication, 0.68 for Childhood Health Assessment Questionnaire (CHAQ) >0, 0.69 for Physical Summary Score (PhS) 0. (PDF 287 kb)

Published
2018
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20. Additional file 7: of Predicting unfavorable long-term outcome in juvenile idiopathic arthritis: results from the Nordic cohort study

Author

Rypdal, Veronika, Arnstad, Ellen, Aalto, Kristiina, Berntson, Lillemor, Ekelund, Maria, Fasth, Anders, Glerup, Mia, Herlin, Troels, Nielsen, Susan, Peltoniemi, Suvi, Zak, Marek, Marite Rygg, Rypdal, Martin, and Nordal, Ellen

Abstract

Figure S2. Receiver operating characteristic (ROC) curves for a test in the Nordic JIA cohort of the prediction model for severe disease course by Guzman et al. The area under the curve (AUC) values were 0.69 for non-achievement of remission off medication, 0.68 for Childhood Health Assessment Questionnaire (CHAQ) >0, 0.69 for Physical Summary Score (PhS) 0. (PDF 287 kb)

Published
2018
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21. Additional file 4: of Predicting unfavorable long-term outcome in juvenile idiopathic arthritis: results from the Nordic cohort study

Author

Rypdal, Veronika, Arnstad, Ellen, Aalto, Kristiina, Berntson, Lillemor, Ekelund, Maria, Fasth, Anders, Glerup, Mia, Herlin, Troels, Nielsen, Susan, Peltoniemi, Suvi, Zak, Marek, Marite Rygg, Rypdal, Martin, and Nordal, Ellen

Subjects
body regions, nervous system, fungi
Abstract

Table S3. Baseline clinical characteristics as predictors of functional disability (CHAQ) in univariate logistic regression. (PDF 125 kb)

Published
2018
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22. Additional file 6: of Predicting unfavorable long-term outcome in juvenile idiopathic arthritis: results from the Nordic cohort study

Author

Rypdal, Veronika, Arnstad, Ellen, Aalto, Kristiina, Berntson, Lillemor, Ekelund, Maria, Fasth, Anders, Glerup, Mia, Herlin, Troels, Nielsen, Susan, Peltoniemi, Suvi, Zak, Marek, Marite Rygg, Rypdal, Martin, and Nordal, Ellen

Subjects
body regions, nervous system, fungi
Abstract

Table S5. Baseline clinical characteristics as predictors of joint damage (JADI-A) in univariate logistic regression. (PDF 161 kb)

Published
2018
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23. Additional file 4: of Predicting unfavorable long-term outcome in juvenile idiopathic arthritis: results from the Nordic cohort study

Author

Rypdal, Veronika, Arnstad, Ellen, Aalto, Kristiina, Berntson, Lillemor, Ekelund, Maria, Fasth, Anders, Glerup, Mia, Herlin, Troels, Nielsen, Susan, Peltoniemi, Suvi, Zak, Marek, Marite Rygg, Rypdal, Martin, and Nordal, Ellen

Subjects
body regions, nervous system, fungi
Abstract

Table S3. Baseline clinical characteristics as predictors of functional disability (CHAQ) in univariate logistic regression. (PDF 125 kb)

Published
2018
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24. Additional file 4 of Opportunistic infections in immunosuppressed patients with juvenile idiopathic arthritis: analysis by the Pharmachild Safety Adjudication Committee

Author

Giancane, Gabriella, Swart, Joost F., Castagnola, Elio, Groll, Andreas H., Horneff, Gerd, Hans-Iko Huppertz, Lovell, Daniel J., Wolfs, Tom, Herlin, Troels, Dolezalova, Pavla, Sanner, Helga, Susic, Gordana, Sztajnbok, Flavio, Maritsi, Despoina, Constantin, Tamas, Vargova, Veronika, Sawhney, Sujata, Marite Rygg, Oliveira, Sheila K., Cattalini, Marco, Bovis, Francesca, Bagnasco, Francesca, Pistorio, Angela, Martini, Alberto, Wulffraat, Nico, and Ruperto, Nicolino

Subjects
musculoskeletal diseases, 3. Good health
Abstract

Additional file 4 Table 2. Concomitant medications administered at the time of “confirmed OI”. Bio: biologic, mtx: methotrexate; ste: systemic steroids; sDMARDs: synthetic disease modifying antirheumatic drugs; *sDMARDs are intendend other than MTX.

25. Additional file 4 of Opportunistic infections in immunosuppressed patients with juvenile idiopathic arthritis: analysis by the Pharmachild Safety Adjudication Committee

Author

Giancane, Gabriella, Swart, Joost F., Castagnola, Elio, Groll, Andreas H., Horneff, Gerd, Hans-Iko Huppertz, Lovell, Daniel J., Wolfs, Tom, Herlin, Troels, Dolezalova, Pavla, Sanner, Helga, Susic, Gordana, Sztajnbok, Flavio, Maritsi, Despoina, Constantin, Tamas, Vargova, Veronika, Sawhney, Sujata, Marite Rygg, Oliveira, Sheila K., Cattalini, Marco, Bovis, Francesca, Bagnasco, Francesca, Pistorio, Angela, Martini, Alberto, Wulffraat, Nico, and Ruperto, Nicolino

Subjects
musculoskeletal diseases, 3. Good health
Abstract

Additional file 4 Table 2. Concomitant medications administered at the time of “confirmed OI”. Bio: biologic, mtx: methotrexate; ste: systemic steroids; sDMARDs: synthetic disease modifying antirheumatic drugs; *sDMARDs are intendend other than MTX.

26. Additional file 3 of Opportunistic infections in immunosuppressed patients with juvenile idiopathic arthritis: analysis by the Pharmachild Safety Adjudication Committee

Author

Giancane, Gabriella, Swart, Joost F., Castagnola, Elio, Groll, Andreas H., Horneff, Gerd, Hans-Iko Huppertz, Lovell, Daniel J., Wolfs, Tom, Herlin, Troels, Dolezalova, Pavla, Sanner, Helga, Susic, Gordana, Sztajnbok, Flavio, Maritsi, Despoina, Constantin, Tamas, Vargova, Veronika, Sawhney, Sujata, Marite Rygg, Oliveira, Sheila K., Cattalini, Marco, Bovis, Francesca, Bagnasco, Francesca, Pistorio, Angela, Martini, Alberto, Wulffraat, Nico, and Ruperto, Nicolino

Subjects
3. Good health
Abstract

Additional file 3 Table 1. Complete table with the frequency of the 682 infections adjudicated by the SAC. Infections were reported after evaluation of the cases available in Pharmachild compared to the pathogens/presentations in the provisional list approved by the Safety Adjudication Committee (SAC). Data are presented as per the MedDRA High Level Term (HLT) and Preferred Term (PT) sorted by frequencies in descending order (HLT and then PT). *For definition see Step 5.

27. Additional file 1 of Opportunistic infections in immunosuppressed patients with juvenile idiopathic arthritis: analysis by the Pharmachild Safety Adjudication Committee

Author

Giancane, Gabriella, Swart, Joost F., Castagnola, Elio, Groll, Andreas H., Horneff, Gerd, Hans-Iko Huppertz, Lovell, Daniel J., Wolfs, Tom, Herlin, Troels, Dolezalova, Pavla, Sanner, Helga, Susic, Gordana, Sztajnbok, Flavio, Maritsi, Despoina, Constantin, Tamas, Vargova, Veronika, Sawhney, Sujata, Marite Rygg, Oliveira, Sheila K., Cattalini, Marco, Bovis, Francesca, Bagnasco, Francesca, Pistorio, Angela, Martini, Alberto, Wulffraat, Nico, and Ruperto, Nicolino

Subjects
3. Good health
Abstract

Additional file 1 figure. Flowchart of the process.

28. Additional file 2 of Opportunistic infections in immunosuppressed patients with juvenile idiopathic arthritis: analysis by the Pharmachild Safety Adjudication Committee

Author

Giancane, Gabriella, Swart, Joost F., Castagnola, Elio, Groll, Andreas H., Horneff, Gerd, Hans-Iko Huppertz, Lovell, Daniel J., Wolfs, Tom, Herlin, Troels, Dolezalova, Pavla, Sanner, Helga, Susic, Gordana, Sztajnbok, Flavio, Maritsi, Despoina, Constantin, Tamas, Vargova, Veronika, Sawhney, Sujata, Marite Rygg, Oliveira, Sheila K., Cattalini, Marco, Bovis, Francesca, Bagnasco, Francesca, Pistorio, Angela, Martini, Alberto, Wulffraat, Nico, and Ruperto, Nicolino

Subjects
3. Good health
Abstract

Additional file 2 figure. Hierarchy of MedDra clinically-validated international medical terminology.

29. Additional file 1 of Opportunistic infections in immunosuppressed patients with juvenile idiopathic arthritis: analysis by the Pharmachild Safety Adjudication Committee

Author

Giancane, Gabriella, Swart, Joost F., Castagnola, Elio, Groll, Andreas H., Horneff, Gerd, Hans-Iko Huppertz, Lovell, Daniel J., Wolfs, Tom, Herlin, Troels, Dolezalova, Pavla, Sanner, Helga, Susic, Gordana, Sztajnbok, Flavio, Maritsi, Despoina, Constantin, Tamas, Vargova, Veronika, Sawhney, Sujata, Marite Rygg, Oliveira, Sheila K., Cattalini, Marco, Bovis, Francesca, Bagnasco, Francesca, Pistorio, Angela, Martini, Alberto, Wulffraat, Nico, and Ruperto, Nicolino

Subjects
3. Good health
Abstract

Additional file 1 figure. Flowchart of the process.

30. Additional file 2 of Opportunistic infections in immunosuppressed patients with juvenile idiopathic arthritis: analysis by the Pharmachild Safety Adjudication Committee

Author

Giancane, Gabriella, Swart, Joost F., Castagnola, Elio, Groll, Andreas H., Horneff, Gerd, Hans-Iko Huppertz, Lovell, Daniel J., Wolfs, Tom, Herlin, Troels, Dolezalova, Pavla, Sanner, Helga, Susic, Gordana, Sztajnbok, Flavio, Maritsi, Despoina, Constantin, Tamas, Vargova, Veronika, Sawhney, Sujata, Marite Rygg, Oliveira, Sheila K., Cattalini, Marco, Bovis, Francesca, Bagnasco, Francesca, Pistorio, Angela, Martini, Alberto, Wulffraat, Nico, and Ruperto, Nicolino

Subjects
3. Good health
Abstract

Additional file 2 figure. Hierarchy of MedDra clinically-validated international medical terminology.

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