1. [Evaluation of damage in subjects exposed to nephrotoxic substances].
- Author
-
Tranchina G, Totaro S, Lo Cascio N, Scaglione C, Picciotto D, Caizza R, and La Porta V
- Subjects
- Acetylglucosaminidase urine, Adult, Aminopeptidases urine, CD13 Antigens, Humans, Kidney Diseases chemically induced, Kidney Diseases diagnosis, Male, Middle Aged, Muramidase urine, Occupational Diseases chemically induced, alpha-Glucosidases urine, Clinical Enzyme Tests, Kidney Tubules, Occupational Diseases diagnosis
- Abstract
Nephritic functionality has been studies, making use of same nephritic enzymes dosage (NAG, AAP, alpha-glucosidase, lysozyme) in three groups of workers (varnishers, metallurgists, plastic manufacture employees) professionally exposed to nephritic damage, and in a control group made up of not professionally exposed to the same hazard subjects. The aim was to precociously detect possible nephritic damage, i.e. before classic nephritic functionality indexes were distorted. An increased enzymuria appeared in those subjects that were exposed to nephrotoxic hazard. Increased enzymuria have been found in only one subject of the control group. We deem it should be useful, to customarily measure out nephritic enzymes as trusted index of tabular damage, in hiring and pensionary control examinations.
- Published
- 1988