1. Association of age of adverse childhood experiences with thalamic volumes and post-traumatic stress disorder in adulthood
- Author
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Nickelas Huffman, Chia-Hao Shih, Andrew S. Cotton, Terrence J. Lewis, Stephen Grider, John T. Wall, Xin Wang, and Hong Xie
- Subjects
thalamus ,adverse childhood experiences (ACEs) ,post-traumatic stress disorder (PTSD) ,structural MRI ,Childhood Age Range Stress Scale (CARSS) ,Neurosciences. Biological psychiatry. Neuropsychiatry ,RC321-571 - Abstract
BackgroundAdverse childhood experiences (ACEs) have been linked to brain development and mental disorders, however, the impact of the age of occurrence of ACEs on thalamic volume and post-traumatic stress disorder (PTSD) after adult trauma remains unclear. This study assessed associations between ACEs at different ages to thalamic volumes and PTSD development following acute adult trauma.MethodsSeventy-nine adult trauma survivors were recruited immediately after trauma. Within 2 weeks of the traumatic event, participants completed the PTSD Checklist (PCL) to assess PTSD symptoms, the Childhood Trauma Questionnaire (CTQ) and Childhood Age Range Stress Scale (CARSS) to evaluate ACEs and perceived stress level at preschool (
- Published
- 2023
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