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Genome editing and gene drive technologies are increasingly gaining attraction in Africa, with researchers exploring their potential applications in agriculture, health and the environment. Acknowledging that robust regulatory frameworks are crucial in facilitating the development and utilization of these technologies, informed decision-making is, however, being impeded by the fragmented information availability and readiness of regulatory authorities on the continent.ObjectivesThis study investigates the regulatory frameworks governing genome editing and gene drive technologies in African countries, identifies common regulatory challenges and proposes actionable solutions.MethodsPrimary data were collected through questionnaires and complemented by analysing existing biosafety regulations from online databases and scientific literature.ResultsOur findings suggest that while a few African countries have recently updated their regulatory frameworks, many are still under discussion. Challenges to development and implementation include limited resources, expertise, awareness, and public resistance.ConclusionThe findings underscore the urgent need for further development in regulatory capacities. By shedding light on these challenges, our study could provide African regulators with valuable insights to guide the formulation of effective regulatory frameworks. Such frameworks are essential for harnessing the potential of genome editing and gene drive technologies while safeguarding human health and the environment in Africa.

Teen dating violence (TDV) victimization is a traumatic experience that can have adverse consequences for adolescents. Current measures that assess TDV do not fully distinguish between psychological and relational forms of aggression, nor do they capture aggressive acts that are common within adolescent relationships. The purpose of this study was to evaluate the psychometric properties of the Teen Dating Aggression Measure (TeDAM) using a sample of 730 Canadian adolescents (M = 15.88 years, SD = 1.23). The measure is an expansion of the Conflict in Adolescent Dating Relationships Inventory and includes items that describe other forms of violence such as coercion and control, along with more traditional indicators of dating violence (e.g., sexual aggression). Factor analyses yielded three factors, namely psychological aggression, sexual and physical aggression, and relational aggression, which were correlated with more frequent cannabis and alcohol use as well as rape myth acceptance. These results provide initial support for the utility of the TeDAM for assessing TDV with adolescents.

Anyone working in biosafety capacity enhancement faces the challenge of ensuring that the impact of a capacity enhancing activity continues and becomes sustainable beyond the depletion of funding. Many training efforts face the limitation of one-off events: they only reach those people present at the time. It becomes incumbent upon the trainees to pass on the training to colleagues as best they can, whilst the demand for the training never appears to diminish. However, beyond the initial effort to establish the basic content, repeating capacity enhancement events in different locations is usually not economically feasible. Also, the lack of infrastructure and other resources needed to support a robust training programme hinder operationalizing a “train-the-trainer” approach to biosafety training. One way to address these challenges is through the use of eLearning modules that can be delivered online, globally, continuously, at low cost, and on an as-needed basis to multiple audiences. Once the modules are developed and peer-reviewed, they can be maintained on a remote server and made available to various audiences through a password-protected portal that delivers the programme content, administers preliminary and final exams, and provides the administrative infrastructure to register users and track their progress through the modules. Crucial to the implementation of such an eLearning programme is an approach in which the modules are intentionally developed together as a cohesive curriculum. Once developed, such a curriculum can be released as a stand-alone programme for the training of governmental risk assessors and regulators or used as accredited components in post-graduate degree programmes in biosafety, at minimal cost to the government or university. Examples from the portfolio of eLearning modules developed by the International Centre for Genetic Engineering and Biotechnology (ICGEB) are provided to demonstrate these key features.