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26 results on '"Gu, Xiaosong"'

4. Identification of Neuronal Cells in Sciatic Nerves of Adult Rats

Author

Liu, Yisheng, Zhou, Songlin, Zhao, Lili, and Gu, Xiaosong

Subjects
Cellular and Molecular Neuroscience, nervous system
Abstract

Prior research generally confirms that there are no neuronal cell bodies in the adult sciatic nerve. However, we occasionally find some neuronal cells in adult rat sciatic nerves, either intact or crush-injured. By whole-mount staining and optical imaging of the hyalinized sciatic nerves for Stmn2 (a specific marker for neuronal cells), we found those neuronal cells with irregular distribution in the sciatic nerves in both crushed model and normal rats. We investigated the identity of those cells and established a cultured sciatic nerve model. Immunohistochemistry evidence both in vivo and in vitro illustrated that some of those cells are mature neurons in sciatic nerves. With single-cell sequencing of neuronal cells in adeno-associated virus (AAV)-infected sciatic nerves, we identified that some of those cells are a kind of neuronal stem-like cells. Then we constructed a Nestin-CreERT2 rat line and traced those cells with fluorescence labeling which was induced by tamoxifen. Interesting, we proved that neuronal stem-like cells could proliferate by combination of EdU incorporation with staining in the sciatic nerves of transgenic rats. Together, the discovery of neuronal cells in adult sciatic nerves will make us aware of the distribution of neurons in the peripheral nervous system. Especially our data suggest that neuronal stem-like cells could proliferate in the sciatic nerves of adult rats.

Published
2022
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8. First-Principle Insight Into the Effects of Oxygen Vacancies on the Electronic, Photocatalytic, and Optical Properties of Monoclinic BiVO4(001)

Author

Xiulong Lv, Yan Qiu, Ying Zhang, Gu Xiaosong, Rui Wang, Qi Li, Qiutong Yan, Yujie Luo, Fangying Ji, Xuan Xu, Fu Shiqi, and He Qian

Subjects
Materials science, Band gap, first-principles method, BiVO4, General Chemistry, Crystal structure, oxygen vacancy, photocatalytic, law.invention, lcsh:Chemistry, chemistry.chemical_compound, pollutant degradation, lcsh:QD1-999, chemistry, X-ray photoelectron spectroscopy, law, Bismuth vanadate, Rhodamine B, Photocatalysis, Physical chemistry, Electron paramagnetic resonance, Monoclinic crystal system
Abstract

In this paper, first-principle calculations were performed to investigate the effects of oxygen (O) vacancies (Ovac) on the crystal structure, electronic distribution, adsorption energies of O2 and H2O and the density of states (DOS) of monoclinic bismuth vanadate (m-BiVO4). Ovac were stable when incorporated into m-BiVO4(001) and increased the adsorption energy of O2. Ovac changed the V3d orbitals of m-BiVO4(001) by adding a new band gap level, causing the redundant electrons of V atoms to become carriers and promoting the separation efficiency of electrons and holes. To verify the first-principle calculations, m-BiVO4 with different Ovac levels was prepared via hydrothermal synthesis. X-ray diffraction (XRD) patterns confirmed the existence of the (001) crystal surface of m-BiVO4. In addition, X-ray photoelectron spectroscopy (XPS) and electron spin resonance (ESR) spectroscopy of m-BiVO4 confirmed the presence of Ovac and demonstrated that, as the Ovac level increased, the number of superoxide radicals (O2-·) and hydroxyl radicals (·OH) produced increased. In addition, m-BiVO4 with a higher Ovac level possessed superior photocatalytic properties to and degraded rhodamine B (RhB) dye nearly 2-fold faster than m-BiVO4 with a lower Ovac level. Finally, the removal rate of RhB increased from 23 to 44%. All experimental results were in good agreement with the first-principle calculated results.

Published
2020
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16. Blood vessel three-dimensional reconstruction of a tissue engineering nerve bridging rat sciatic nerve injury

Author

Yi Sheng, Gu Xiaosong, Gong Leilei, Wang Yaxian, and Wang Hongkui

Subjects
medicine.medical_specialty, Histology, Bridging (networking), business.industry, Biomedical Engineering, Bioengineering, Anatomy, Sciatic nerve injury, medicine.disease, Surgery, medicine.anatomical_structure, Tissue engineering, medicine, Epineurial repair, business, Biotechnology, Blood vessel
Published
2016
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18. Joint use of chitosan-PGA nerve guidance conduits and bone marrow mesenchymal stem cells to repair 50mm long median nerve defect combined 80mm long ulnar nerve defect in the human upper arm

Author

Gu Xiaokun, Yi Sheng, Gu Jianhui, Gu Xiaosong, Liu Dan, Qian Zhongwei, Xue Chengbin, Deng Aidong, and Gu Yun

Subjects
Histology, business.industry, Biomedical Engineering, Medicine, Bioengineering, Anatomy, Epineurial repair, Ulnar nerve, business, Bone marrow mesenchymal stem cells, Median nerve, Biotechnology
Published
2016
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19. Application of bone marrow mesenchymal stem cell-derived extracellular matrix in peripheral nerve tissue engineering

Author

Gu Xiaosong, Gu Yun, Xue Chenbin, Li Zhenmeiyu, and Yi Shen

Subjects
Pathology, medicine.medical_specialty, Histology, business.industry, Mesenchymal stem cell, Biomedical Engineering, Nerve guidance conduit, Bioengineering, Extracellular matrix, medicine.anatomical_structure, Tissue engineering, Peripheral nerve, Bone cell, medicine, Bone marrow, business, Biotechnology, Stem cell transplantation for articular cartilage repair
Published
2016
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