1. The Role of Heart Rate on the Associations Between Body Composition and Heart Rate Variability in Children With Overweight/Obesity: The ActiveBrains Project
- Author
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Jose Mora-Gonzalez, Pablo Molina-Garcia, Socorro Navarrete, Abel Plaza-Florido, Rosa Maria Lozano, Jairo H. Migueles, María Rodriguez-Ayllon, Irene Esteban-Cornejo, Jerzy Sacha, Francisco B. Ortega, Cristina Cadenas-Sanchez, and Nathalie Michels
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medicine.medical_specialty ,Physiology ,CARDIAC AUTONOMIC MODULATION ,POWER ,HRV ,030204 cardiovascular system & hematology ,Overweight ,lcsh:Physiology ,03 medical and health sciences ,0302 clinical medicine ,Physiology (medical) ,Internal medicine ,Heart rate ,Medicine and Health Sciences ,medicine ,Heart rate variability ,030212 general & internal medicine ,OBESE ,Original Research ,Balance (ability) ,adiposity ,preadolescents ,lcsh:QP1-981 ,business.industry ,Overweight obesity ,Confounding ,fat mass ,Cardiorespiratory fitness ,sympathetic ,medicine.disease ,Obesity ,MARKER ,Cardiology ,medicine.symptom ,CARDIORESPIRATORY FITNESS ,business ,parasympathetic ,circulatory and respiratory physiology - Abstract
The authors would like to thank all the participants who volunteered for this investigation. This work is the part of a Ph.D. Thesis conducted in the Biomedicine Doctoral Studies of the University of Granada, Spain., The Supplementary Material for this article can be found online at: https://www.frontiersin.org/articles/10.3389/fphys.2019.00895/full#supplementary-material, Background: Heart rate variability (HRV) is negatively associated with body mass index and adiposity in several populations. However, less information is available about this association in children with overweight and obesity, especially severe/morbid obesity, taking into consideration the dependence of HRV on heart rate (HR). Objectives: (1) to examine associations between body composition measures and HRV, (2) to study differences in HRV between children with overweight and severe/morbid obesity; and (3) to test whether relationships and differences tested in objectives 1 and 2, respectively are explained by the dependency of HRV on HR. Methods: A total of 107 children with overweight/obesity (58% boys, 10.03 ± 1.13 years) participated in this study. Body composition measures were evaluated by Dual-energy X-ray absorptiometry (DXA). HRV parameters were measured with Polar RS800CX®. Results: Body composition measures were negatively associated with HRV indicators of parasympathetic activity (β values ranging from −0.207 to −0.307, all p < 0.05). Children with severe/morbid obesity presented lower HRV values with respect to children with overweight/mild obesity in HRV parameters indicators of parasympathetic activity (p = 0.035). All associations disappeared after further adjustment for HR (all p > 0.05). Conclusion: All associations between adiposity/obesity and HRV could be explained by HR, suggesting a key confounding role of HR in HRV studies in children with weight disturbances., This work was supported by the Spanish Ministry of Economy and Competitiveness (Reference DEP2013-47540 and DEP2016-79512-R). CC-S was supported by a grant from the Spanish Ministry of Economy and Competitiveness (BES-2014-068829). AP-F, JM, and JM-G were supported by the Spanish Ministry of Education, Culture and Sport (FPU 16/02760, FPU15/02645, and FPU14/06837, respectively). IE-C was supported by a grant from the Alicia Koplowitz Foundation and for the Spanish Ministry of Science and Innovation (IJCI-2017-33642). MR-A was supported by the National Operational Programme on Youth Employment. Additional support was obtained from the Unit of Excellence on Exercise and Health (UCEES) and EXERNET Research Network on Exercise and Health in Special Populations (DEP2005-00046/ACTI). This work was partially funded by the University of Granada, Plan Propio de Investigación 2016, Excellence actions: Units of Excellence; Unit of Excellence on Exercise and Health (UCEES), and by the Junta de Andalucía, Consejería de Conocimiento, Investigación y Universidades and European Regional Development Fund (ERDF), ref. SOMM17/6107/UGR.
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- 2019