1. Ibuprofen Dependence: A Case Report
- Author
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Marie Grall-Bronnec, François Etcheverrigaray, Pascale Jolliet, M.-C. Blanchet, and Caroline Victorri-Vigneau
- Subjects
Psychiatry and Mental health ,Cannabinoid Receptor Modulators ,business.industry ,Medicine ,Pharmacology (medical) ,General Medicine ,Pharmacology ,business ,Ibuprofen ,medicine.drug - Abstract
Ibuprofen is currently widely prescribed and has not been reported to produce dependence. We report the case of a 17-year old patient who presented many positive psychics symptoms related to a pharmacological dependence. During the treatment, she adjusted herself posology as she developed withdrawal symptoms. Pharmacological evidences (effect on COX-1 and COX-2, FAAH and PPARs) allow us to formulate hypotheses explaining this effect.
- Published
- 2014
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