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4. Interferon-α bei Condylomata acuminata und juvenilem Diabetes mellitus

Author

Gerd Gross, N. Drees, A. Roussaki, and H. Ikenberg

Subjects
medicine.medical_specialty, biology, business.industry, Insulin, medicine.medical_treatment, virus diseases, Alpha interferon, General Medicine, medicine.disease, law.invention, Endocrinology, law, Concomitant, Internal medicine, Total dose, Diabetes mellitus, biology.protein, medicine, Recombinant DNA, Juvenile diabetes mellitus, Antibody, skin and connective tissue diseases, business
Abstract

Persistent condylomata acuminata in a 21-year-old patient with diabetes mellitus were treated with highly purified interferon-alpha (IFN-alpha) obtained by recombinant DNA technology. Daily dose was 1.5 X 10(6) IU, given subcutaneously. Already during treatment the condylomata regressed. Two weeks after the end of therapy, i.e. after a total dose of 10.5 X 10(6) IU IFN-alpha, all condylomata had completely receded. Blood glucose levels remained constant with concomitant insulin therapy. Toxic side-effects or antibodies to IFN-alpha were not observed.

Published
2008
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