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Start Over Author "Karl Richard Gibson" Publisher georg thieme verlag kg
2 results on '"Karl Richard Gibson"'

1. Synthetic Studies on a Nonsteroidal Progesterone Metabolite: Regioselective N-Alkylation of an Activated Pyrazole

Author

Karl Richard Gibson, Yann C. Lecouturier, Paul A. Bradley, Malcolm C. Mackenny, Toby J. Underwood, Cedric Poinsard, Pieter D. de Koning, and Inaki Morao

Subjects
chemistry.chemical_compound, chemistry, Stereochemistry, Metabolite, Organic Chemistry, Progesterone receptor, Regioselectivity, Organic chemistry, Halogenation, Alkylation, Pyrazole, Carbonylation
Abstract

This paper describes the large-scale synthesis of a progesterone receptor metabolite. The key step in this sequence was the regioselective pyrazole N-alkylation.

Published
2010
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