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2. Pulmonary Hypertension in COPD: Is it worth looking for?

Author

Matthes, S., Priegnitz, C., Treml, M., Anduleit, N., Richter, K., Kietzmann, I, Herkenrath, S. D., Hagmeyer, L., Milger, K., Randerath, W. J., Matthes, S., Priegnitz, C., Treml, M., Anduleit, N., Richter, K., Kietzmann, I, Herkenrath, S. D., Hagmeyer, L., Milger, K., and Randerath, W. J.

Published
2020

9. Position Paper for the State of the Art Application of Respiratory Support in Patients with COVID-19 German Respiratory Society

Author

Pfeifer, M., Ewig, S., Voshaar, T., Randerath, W., Bauer, T., Geiseler, J., Dellweg, D., Westhoff, M., Windisch, W., Schoenhofer, B., Kluge, S., Lepper, P. M., Pfeifer, M., Ewig, S., Voshaar, T., Randerath, W., Bauer, T., Geiseler, J., Dellweg, D., Westhoff, M., Windisch, W., Schoenhofer, B., Kluge, S., and Lepper, P. M.

Abstract

Against the background of the pandemic caused by infection with the SARS-CoV-2, the German Society for Pneumology and Respiratory Medicine (DGP e.V.), in cooperation with other associations, has designated a team of experts in order to answer the currently pressing questions about therapy strategies in dealing with COVID-19 patients suffering from acute respiratory insufficiency (ARI). The position paper is based on the current knowledge that is evolving daily. Many of the published and cited studies require further review, also because many of them did not undergo standard review processes.Therefore, this position paper is also subject to a continuous review process and will be further developed in cooperation with the other professional societies. This position paper is structured into the following five topics: 1. Pathophysiology of acute respiratory insufficiency in patients without immunity infected with SARS-CoV-2 2. Temporal course and prognosis of acute respiratory insufficiency during the course of the disease 3. Oxygen insufflation, high-flow oxygen, non-invasive ventilation and invasive ventilation with special consideration of infectious aerosol formation 4. Non-invasive ventilation in ARI 5. Supply continuum for the treatment of ARI Key points have been highlighted as core statements and significant observations. Regarding the pathophysiological aspects of acute respiratory insufficiency (ARI), the pulmonary infection with SARS-CoV-2 COVID-19 runs through three phases: early infection, pulmonary manifestation and severe hyperinflammatory phase. There are differences between advanced COVID-19-induced lung damage and those changes seen in Acute Respiratory Distress Syndromes (ARDS) as defined by the Berlin criteria. In a pathophysiologically plausible - but currently not yet histopathologically substantiated - model, two types (L-type and H-type) are distinguished, which correspond to an early and late phase. This distinction can be taken into considerati

Published
2020

15. Different Prevalences of Pneumological Disease Patterns in Outpatient and Inpatient Care

Author

Herkenrath, S., Muelleneisen, N., Treml, M., Kietzmann, I., Hagmeyer, L., Randerath, W., Herkenrath, S., Muelleneisen, N., Treml, M., Kietzmann, I., Hagmeyer, L., and Randerath, W.

Abstract

Background Evaluating the focus of treatment in pneumological inpatient and outpatient care is of special interest due to its impact on physician, patient and research. This work describes differences and commonalities in the focus of treatment of current pneumological inpatient and outpatient care and discusses their impact on patient, physician and research. Methods This study compares the inpatient and outpatient sector based on the prevalence of ICD codes of a pneumological specialist clinic (5.211 cases of 2016) and the most prevalent ICD-10 codes of pneumology practices in the third quarter 2016, published by the Association of Statutory Health Insurance Physicians North Rhine (Kassenarztliche Vereinigung Nordrhein, 142.431 cases). Results Whereas the proportion of many pneumological disease patterns treated in physicians' practices and hospitals is similar, the relative frequencies of specific diseases differ considerably between the two. Treatment of allergic conditions such as allergic rhinopathy and bronchial asthma is mostly done on an outpatient basis while respiratory insufficiency and lung carcinoma constitute domains of pneumological inpatient care. Conclusion Despite many commonalities in the focus of treatment in pneumological inpatient and outpatient care, there are also substantial differences between the two. These affect medical training, the conduct of clinical studies, and in particular, patient care. In order to maintain a high level of medical care in all areas of pneumology a close exchange between inpatient and outpatient sector seems crucial. In the end, the availability of medical expertise across both sectors will benefit all: physicians, patients and medical science.

Published
2019

18. Endoskopische Lungenvolumenreduktion

Author

Hagmeyer L and Randerath W

Subjects
Lung volume reduction, medicine.medical_specialty, Text mining, business.industry, Medicine, General Medicine, Radiology, business
Published
2014

24. Expertentreffen COPD: Exazerbation der COPD

Author

Lorenz, J., additional, Bals, R., additional, Dreher, M., additional, Jany, B., additional, Koczulla, R., additional, Pfeifer, M., additional, Randerath, W., additional, Steinkamp, G., additional, Taube, C., additional, Watz, H., additional, and Windisch, W., additional

Published
2017
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27. Optimierung der CPAP-Adaptation durch Feedback-gestützte Trainingsphasen bei Patienten mit obstruktivem Schlafapnoe-Syndrom

Author

Randerath W, Karl-Heinz Rühle, and Quessada J

Subjects
Pulmonary and Respiratory Medicine, medicine.medical_specialty, business.industry, medicine.disease, Exercise time, Obstructive sleep apnea, Sleep apnoea syndrome, Internal medicine, Fixation (visual), Physical therapy, Cardiology, Medicine, In patient, business, Accommodation
Abstract

Mask fitting and accommodation of CPAP-devices are of great importance. Only by accommodation over several hours, problems concerning mask size and fixation of mask are recognised and solved. Many patients overestimate the time they needed for achieving accommodation. We therefore asked whether by visualizing the time required for accommodation the accommodation time can be prolonged. Additionally we compared the subjective estimation on the time with the objectively measured time. We studied 20 patients with sleep apnoea syndrome, 13 men and 7 women, age 53 +/- 4 years, apnoea/hypopnoea index 32 +/- 16, lowest O2 saturation 83 +/- 6%. In a randomized cross-over study, a clock with a large 7 segment-display was either not visible in one setting, so that the patient had no control of the training-time, or the time was visible on the display. Thus the patient could possibly be motivated to increase his time of CPAP-accommodation during the day. The pressure-controlled clock counted only the time during which the pressure was above 4 HPa. In the setting with visible time-counter the accommodation time was 265.8 +/- 114 min, if the counter was not visible, time was only 210.8 +/- 91 min. If the patient cannot observe the time-counter he over-estimates the objectively measured time by half an hour (247.2 +/- 97.5 estimated vs. 210.8 +/- 91.0 actually). Thus the self-control of CPAP-accommodation by a visible clock leads to a significant prolongation of the exercise time. The estimation by the patient is only a limited means to evaluate the time of CPAP accommodation during the day.

Published
1999

46. COPD und Studien

Author

Lorenz, J., primary, Bals, R., additional, Gillissen, A., additional, Magnussen, H., additional, Pfeifer, M., additional, Randerath, W., additional, Schultze-Werninghaus, G., additional, Steinkamp, G., additional, Teschler, H., additional, Vogelmeier, C., additional, and Worth, H., additional

Published
2011
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