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This article discusses the potential of long noncoding RNAs (lncRNAs) in understanding thoracic aortic diseases. The researchers identified two lncRNAs, TMEM72-AS1 and LINC00632, that are expressed in vascular smooth muscle cells and differ between dilated and non-dilated areas of the aorta. The expression of these lncRNAs was significantly higher in dilated areas, particularly in tissues from patients with bicuspid aortic valve (BAV) and aortic regurgitation (AI). The findings suggest that these lncRNAs could be potential targets for diagnostic and therapeutic interventions in thoracic aortic diseases. [Extracted from the article]

This article discusses the symptoms, lesions, and risk factors of stroke following infective endocarditis (IE). The study analyzed 81 patients who suffered a stroke after IE and found that motor/sensory deficits were the main symptoms. The most common form of stroke was partial anterior circulation stroke. Native mitral valve endocarditis was identified as a risk factor for stroke, while prosthetic valve endocarditis was not. There was no significant difference in ICU stay or in-hospital mortality between the groups. [Extracted from the article]

This article examines the outcomes of patients with acute type A aortic dissection (ATAD) who underwent surgery after receiving preoperative cardiopulmonary resuscitation (CPR). The study analyzed data from the European registry of type A aortic dissection (ERTAAD) and included 2,266 ATAD patients from 19 European centers. The results showed that patients who required CPR before surgery had higher rates of postoperative complications, including stroke, heart failure, and the need for dialysis. They also had a higher 30-day mortality rate. However, when additional risk factors such as low ejection fraction, advanced age, and myocardial ischemia were present, the analysis did not indicate a significant increase in mortality, suggesting that surgery may still be a viable option for these patients. [Extracted from the article]

This article discusses the influence of delirium on the outcomes of cardiac surgery in elderly patients. The study analyzed data from 684 patients aged 80 years and older who underwent cardiac surgery between 2012 and 2019. It was found that 14.6% of these patients experienced postoperative delirium. The study identified several risk factors for delirium, including chronic obstructive pulmonary disease (COPD), duration of ventilation, and length of stay in the intensive care unit (ICU). The findings suggest that measures should be taken to prevent delirium in elderly patients undergoing cardiac surgery. [Extracted from the article]