1. Barriers to early infant diagnosis of HIV in the Wa Municipality and Lawra District of Upper West Region, Ghana.
- Author
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Nuoh RD, Nyarko KM, Noora CL, Addo-Lartey A, Nortey P, Nuolabong C, Lartey M, and Kenu E
- Subjects
- Adult, Case-Control Studies, Early Diagnosis, Female, Ghana epidemiology, HIV genetics, HIV Infections epidemiology, Humans, Infant, Infant, Newborn, Male, Polymerase Chain Reaction, HIV Infections diagnosis, HIV Infections transmission, Infectious Disease Transmission, Vertical
- Abstract
Objective: We identified socio-demographic, health system and psycho-social barriers to Early Infant Diagnosis (EID) of HIV in the Upper West Region of Ghana., Design: An unmatched case control study of 96 cases and 96 controls was conducted in the ART centers in Lawra district and Wa Municipality between December 2014 and April 2015., Setting: A public health facility., Participants: We defined a case as an HIV positive mother with an exposed infant who received EID service between January 2011 and December 2014. A control was defined as HIV Positive Mother with an exposed infant who did not receive EID services between January 2011 and December 2014., Main Outcome: EID by dry blood spot Deoxyribonucleic acid Polymerase chain reaction., Results: A total of 192 mother-infant pairs were assessed. The mean age of infants at testing for cases was 17.3±14.9 weeks. Mother-to-child-transmission-rate was 2.3%. Factors associated with EID testing included: mother being formally employed (cOR=2.0: 95%CI:1.1-3.8), maternal formal education (cOR=2.0, 95%CI: 1.1-3.6) and maternal independent source of income (cOR 2.2, 95%CI 1.2-4.1). After adjusting for confounders, maternal independent income source was associated with EID testing (aOR 2.2, 95%CI 1.2-4.1). Median turn-around time of EID result was 11 weeks (IQR 4-27 weeks)., Conclusion: Women need to be empowered to gain an independent source of income. This can help maximize the benefits of e-MTCT and increase EID in the Upper West Region of Ghana., Funding: This work was funded by the authors., Competing Interests: Conflict of interest: None declared, (Copyright © The Author(s).)
- Published
- 2020
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