1. Contribution of Fourier-domain optical coherence tomography to the diagnosis of keratoconus progression
- Author
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Nacim Bouheraoua, R Atia, Otman Sandali, Sofiane Ouanezar, Cristina Georgeon, Vincent Borderie, Laurent Laroche, Cyrille Temstet, Centre Hospitalier National d'Ophtalmologie des Quinze-Vingts (CHNO), Institut de la Vision, and Centre National de la Recherche Scientifique (CNRS)-Sorbonne Université (SU)-Institut National de la Santé et de la Recherche Médicale (INSERM)
- Subjects
medicine.medical_specialty ,Keratoconus ,genetic structures ,[SDV]Life Sciences [q-bio] ,law.invention ,03 medical and health sciences ,0302 clinical medicine ,Optical coherence tomography ,law ,Ectasia ,Ophthalmology ,Medicine ,Prospective cohort study ,Dioptre ,medicine.diagnostic_test ,Receiver operating characteristic ,Keratometer ,business.industry ,Corneal topography ,medicine.disease ,eye diseases ,Sensory Systems ,3. Good health ,030221 ophthalmology & optometry ,Surgery ,sense organs ,business ,030217 neurology & neurosurgery - Abstract
PURPOSE To determine the anatomic criteria for diagnosing keratoconus progression by corneal optical coherence tomography (OCT). SETTING Quinze-Vingts National Ophthalmology Hospital, Paris, France. DESIGN Prospective case series. METHODS Scanning-slit corneal topography (Orbscan II) and Fourier-domain corneal OCT (RTVue) were performed in eyes with mild to moderate keratoconus (progressive or nonprogressive [stable] ectasia) at each examination to assess the keratoconus. Disease progression was defined as an increase of at least 1.0 diopter (D) in the steepest keratometry (K) measurement over 6 months. RESULTS Of the 134 eyes of 134 patients with mild to moderate keratoconus, 98 had had progressive ectasia and 36 nonprogressive ectasia. The mean maximum K increased significantly in the progressive group (2.1 D ± 1.2 [SD], P
- Published
- 2019
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