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3 results on '"G. Nonglaton"'

1. Optimum functionalization of Si nanowire FET for electrical detection of DNA hybridization

Author

R. Midahuen, B. Previtali, C. Fontelaye, G. Nonglaton, V. Stambouli, S. Barraud, Commissariat à l'énergie atomique et aux énergies alternatives - Laboratoire d'Electronique et de Technologie de l'Information (CEA-LETI), Direction de Recherche Technologique (CEA) (DRT (CEA)), Commissariat à l'énergie atomique et aux énergies alternatives (CEA)-Commissariat à l'énergie atomique et aux énergies alternatives (CEA), Laboratoire des matériaux et du génie physique (LMGP ), Institut de Chimie du CNRS (INC)-Centre National de la Recherche Scientifique (CNRS)-Institut polytechnique de Grenoble - Grenoble Institute of Technology (Grenoble INP ), Université Grenoble Alpes (UGA)-Université Grenoble Alpes (UGA), ANR-11-LABX-0003,ARCANE,Grenoble, une chimie bio-motivée(2011), and ANR-17-EURE-0003,CBH-EUR-GS,CBH-EUR-GS(2017)

Subjects
[PHYS]Physics [physics], Biosensing, DNA, silicon nanowire, Electrical and Electronic Engineering, ISFET, Electronic, Optical and Magnetic Materials, Biotechnology
Abstract

International audience; In this work, we demonstrate a wafer-scale fabrication of biologically sensitive Si nanowire FET for pH sensing and electrical detection of deoxyribonucleic acid (DNA) hybridization. Based on conventional "top-down" CMOS compatible technology, our bioFETs explore a wide range of design (nanowires (NW), nanoribbons (NR), and honeycomb (HC) structures) with opening access scaled down to only 120 nm. After device fabrication, I DS-V BG transfer and I DS-V DS output characteristics show a conventional n-type FET behavior with an I ON /I OFF value higher than 10 5 , as well as an increase of threshold voltage as the NW width is reduced. Then, using a capacitive coupling in our dually-gated Si bioFETs, the pH sensitivity is enhanced with a pH response up to 600 mV/pH. Finally, we successfully detected an increase of threshold voltage of n-type silicon nanowires (SiNWs) due to hybridized target DNA molecules.

Published
2022

2. Wafer-scale fabrication of biologically sensitive Si nanowire FET: from pH sensing to electrical detection of DNA hybridization

Author

G. Nonglaton, Bernard Previtali, V. Stambouli, R. Midahuen, Sylvain Barraud, C. Fontelaye, Commissariat à l'énergie atomique et aux énergies alternatives - Laboratoire d'Electronique et de Technologie de l'Information (CEA-LETI), Direction de Recherche Technologique (CEA) (DRT (CEA)), Commissariat à l'énergie atomique et aux énergies alternatives (CEA)-Commissariat à l'énergie atomique et aux énergies alternatives (CEA), Laboratoire des matériaux et du génie physique (LMGP ), Institut de Chimie du CNRS (INC)-Centre National de la Recherche Scientifique (CNRS)-Institut polytechnique de Grenoble - Grenoble Institute of Technology (Grenoble INP ), and Université Grenoble Alpes (UGA)-Université Grenoble Alpes (UGA)

Subjects
Capacitive coupling, Fabrication, Materials science, Silicon, business.industry, Nanowire, chemistry.chemical_element, [CHIM.MATE]Chemical Sciences/Material chemistry, Threshold voltage, CMOS, chemistry, Optoelectronics, Wafer, Field-effect transistor, business, ComputingMilieux_MISCELLANEOUS
Abstract

In this work, a wafer-scale fabrication of biologically sensitive Si nanowire FET is demonstrated for pH sensing and electrical detection of DNA hybridization. Based on conventional “top-down” CMOS compatible technology, our bioFETs explore a wide range of design (nanowires [NW], nanoribbons [NR], and honeycomb [HC] structures) with opening access scaled down to only 120 nm. After device fabrication, I DS -V BG transfer and I DS -V DS output characteristics show a conventional n-type FET behavior with an I ON /I OFF value higher than 105, as well as an increase of threshold voltage as the NW width is reduced. Then, using a capacitive coupling in our dual-gated Si bioFETs, the pH sensitivity is enhanced with a pH response up to 600 mV/pH. Finally, the increase of threshold voltage of n-type SiNWs due to hybridized target DNA molecules is successfully detected.

Published
2021

3. Capacitive micromachined ultrasonic transducers leak detection by dye penetrant test

Author

G. Nonglaton, A. Nowodzinski, David Bouchu, B. Fain, S. Giroud, V. Mourier, O. Ndjoye-Kogou, Commissariat à l'énergie atomique et aux énergies alternatives - Laboratoire d'Electronique et de Technologie de l'Information (CEA-LETI), Direction de Recherche Technologique (CEA) (DRT (CEA)), Commissariat à l'énergie atomique et aux énergies alternatives (CEA)-Commissariat à l'énergie atomique et aux énergies alternatives (CEA), the Fonds européen de développement régional (FEDER 3431-35438)., and ANR-10-TECS-0007,THERANOS,Plateforme ultrasonore de diagnostic et thérapie ciblée(2010)

Subjects
Materials science, Acoustics, Dye penetrant inspection, Condensed Matter Physics, 01 natural sciences, Atomic and Molecular Physics, and Optics, 030218 nuclear medicine & medical imaging, Surfaces, Coatings and Films, Electronic, Optical and Magnetic Materials, 03 medical and health sciences, [SPI]Engineering Sciences [physics], 0302 clinical medicine, Capacitive micromachined ultrasonic transducers, 0103 physical sciences, Leak detection, Electrical and Electronic Engineering, Safety, Risk, Reliability and Quality, 010301 acoustics
Abstract

International audience; Dye penetrant test has been used to detect non hermetic capacitive micromachined ultrasonic transducers (CMUTs). The method has proven its ability to highlight faulty CMUTs membranes among more than hundreds of CMUTs membranes. The fluorescence microscopy image highlights the defective CMUTs with a strong contrast and respecting the shape of the CMUTs, which makes it possible to design robust faulty CMUT automatic identification algorithms. Scanning electron microscopy has been performed in order to check the reliability the detection of the non-hermetic CMUTs. Observations confirmed the reliability of the method.

Published
2020

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