12 results on '"Lionel Bouvet"'
Search Results
2. Anaesthesia and intensive care in obstetrics during the COVID-19 pandemic
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Estelle Morau, Lionel Bouvet, Hawa Keita, Florence Vial, Marie Pierre Bonnet, Martine Bonnin, Agnès Le Gouez, Dominique Chassard, Frédéric J. Mercier, Dan Benhamou, Marie Pïerre Bonnet, Anne Sophie Bouthors, Adeline Castel, Pierre Yves Dewandre, Catherine Fisher, Benjamin Julliac, Thibault Rackelboom, Anne Wernet, Centre Hospitalier Universitaire de Nîmes (CHU Nîmes), Service d'anesthésie-réanimation [Centre Hospitalier Lyon Sud - HCL], Centre Hospitalier Lyon Sud [CHU - HCL] (CHLS), Hospices Civils de Lyon (HCL)-Hospices Civils de Lyon (HCL), Service d'Anesthésie Réanimation [CHU Necker], Assistance publique - Hôpitaux de Paris (AP-HP) (AP-HP)-CHU Necker - Enfants Malades [AP-HP], Assistance publique - Hôpitaux de Paris (AP-HP) (AP-HP), Pharmacologie et évaluations thérapeutiques chez l'enfant et la femme enceinte (URP_7323), Université de Paris (UP), Service de Réanimation Médicale [CHRU Nancy], Centre Hospitalier Régional Universitaire de Nancy (CHRU Nancy), Equipe 1 : EPOPé - Épidémiologie Obstétricale, Périnatale et Pédiatrique (CRESS - U1153), Centre de Recherche Épidémiologie et Statistique Sorbonne Paris Cité (CRESS (U1153 / UMR_A_1125 / UMR_S_1153)), Conservatoire National des Arts et Métiers [CNAM] (CNAM)-Université Sorbonne Paris Cité (USPC)-Institut National de la Santé et de la Recherche Médicale (INSERM)-Université de Paris (UP)-Institut National de Recherche pour l’Agriculture, l’Alimentation et l’Environnement (INRAE)-Conservatoire National des Arts et Métiers [CNAM] (CNAM)-Université Sorbonne Paris Cité (USPC)-Institut National de la Santé et de la Recherche Médicale (INSERM)-Université de Paris (UP)-Institut National de Recherche pour l’Agriculture, l’Alimentation et l’Environnement (INRAE), CHU Trousseau [APHP], Assistance publique - Hôpitaux de Paris (AP-HP) (AP-HP)-Sorbonne Université (SU), CHU Estaing [Clermont-Ferrand], CHU Clermont-Ferrand, AP-HP - Hôpital Antoine Béclère [Clamart], Université Paris-Saclay, AP-HP Hôpital Bicêtre (Le Kremlin-Bicêtre), Hôpital Femme Mère Enfant [CHU - HCL] (HFME), Hospices Civils de Lyon (HCL), Université Paris Cité (UPCité), Conservatoire National des Arts et Métiers [CNAM] (CNAM), HESAM Université - Communauté d'universités et d'établissements Hautes écoles Sorbonne Arts et métiers université (HESAM)-HESAM Université - Communauté d'universités et d'établissements Hautes écoles Sorbonne Arts et métiers université (HESAM)-Université Sorbonne Paris Cité (USPC)-Institut National de la Santé et de la Recherche Médicale (INSERM)-Université Paris Cité (UPCité)-Institut National de Recherche pour l’Agriculture, l’Alimentation et l’Environnement (INRAE)-Conservatoire National des Arts et Métiers [CNAM] (CNAM), HESAM Université - Communauté d'universités et d'établissements Hautes écoles Sorbonne Arts et métiers université (HESAM)-HESAM Université - Communauté d'universités et d'établissements Hautes écoles Sorbonne Arts et métiers université (HESAM)-Université Sorbonne Paris Cité (USPC)-Institut National de la Santé et de la Recherche Médicale (INSERM)-Université Paris Cité (UPCité)-Institut National de Recherche pour l’Agriculture, l’Alimentation et l’Environnement (INRAE), Obstetric Anaesthesia and Critical Care Club Working Group: Dan Benhamou, Marie Pïerre Bonnet, Martine Bonnin, Anne Sophie Bouthors, Lionel Bouvet, Adeline Castel, Dominique Chassard, Pierre Yves Dewandre, Catherine Fisher, Benjamin Julliac, Hawa Keita, Frédéric J Mercier, Estelle Morau, Thibault Rackelboom, Florence Vial, Anne Wernet, and CCSD, Accord Elsevier
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Pregnancy, High-Risk ,Critical Care and Intensive Care Medicine ,Doulas ,Anaesthesia ,Health personnel ,0302 clinical medicine ,030202 anesthesiology ,Pregnancy ,Pandemic ,Infection control ,Thrombophilia ,030212 general & internal medicine ,Pregnancy Complications, Infectious ,Fetal Monitoring ,ComputingMilieux_MISCELLANEOUS ,Cross Infection ,Respiratory Distress Syndrome ,[SDV.MHEP] Life Sciences [q-bio]/Human health and pathology ,Prenatal Care ,General Medicine ,Telemedicine ,3. Good health ,Occupational Diseases ,Female ,Coronavirus Infections ,medicine.medical_specialty ,2019-20 coronavirus outbreak ,Infectious Disease Transmission, Patient-to-Professional ,Coronavirus disease 2019 (COVID-19) ,Critical Care ,Health Personnel ,Pneumonia, Viral ,Prenatal care ,03 medical and health sciences ,Betacoronavirus ,Intensive care ,medicine ,Disease Transmission, Infectious ,Anesthesia, Obstetrical ,Humans ,Labor, Induced ,Pandemics ,Personal Protective Equipment ,Patient Care Team ,Infection Control ,business.industry ,Cesarean Section ,Diagnostic Tests, Routine ,SARS-CoV-2 ,Infant, Newborn ,COVID-19 ,Obstetric ,Delivery, Obstetric ,Infectious Disease Transmission, Vertical ,Anesthesiology and Pain Medicine ,Emergency medicine ,Analgesia, Obstetrical ,Analgesia ,business ,[SDV.MHEP]Life Sciences [q-bio]/Human health and pathology ,Maternal morbidity - Abstract
International audience; No abstract available
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- 2020
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3. Can Thoracic Ultrasound on Admission Predict the Outcome of Critically Ill Patients with SARS-CoV-2? A French Multi-Centric Ancillary Retrospective Study
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Bernard Allaouchiche, Guillaume Besch, Lionel Bouvet, Charlotte Arbelot, Alexandre Lopez, Florian Bazalguette, Laurent Zieleskiewicz, Laurent Muller, Gary Duclos, Marc Leone, Mohamed Boucekine, Neyla Mohammedi, Gauthier Mathon, Mathieu Gazon, Service Anesthésie et Réanimation [Hôpital Nord - APHM], Aix Marseille Université (AMU)-Assistance Publique - Hôpitaux de Marseille (APHM)- Hôpital Nord [CHU - APHM], Agressions Pulmonaires et Circulatoires dans le Sepsis - UR (APCSé), VetAgro Sup - Institut national d'enseignement supérieur et de recherche en alimentation, santé animale, sciences agronomiques et de l'environnement (VAS), Aix-Marseille Université - École de médecine (AMU SMPM MED), Aix-Marseille Université - Faculté des sciences médicales et paramédicales (AMU SMPM), Aix Marseille Université (AMU)-Aix Marseille Université (AMU), Marqueurs pronostiques et facteurs de régulations des pathologies cardiaques et vasculaires - UFC ( EA 3920) (PCVP / CARDIO), Centre Hospitalier Régional Universitaire de Besançon (CHRU Besançon)-Université de Franche-Comté (UFC), Université Bourgogne Franche-Comté [COMUE] (UBFC)-Université Bourgogne Franche-Comté [COMUE] (UBFC), CIC CHU Lyon (inserm), Université Claude Bernard Lyon 1 (UCBL), Université de Lyon-Université de Lyon-Institut National de la Santé et de la Recherche Médicale (INSERM), Centre recherche en CardioVasculaire et Nutrition = Center for CardioVascular and Nutrition research (C2VN), Aix Marseille Université (AMU)-Institut National de la Santé et de la Recherche Médicale (INSERM)-Institut National de Recherche pour l’Agriculture, l’Alimentation et l’Environnement (INRAE), Marqueurs pronostiques et facteurs de régulations des pathologies cardiaques et vasculaires - UFC ( UR 3920) (PCVP / CARDIO), Microbes évolution phylogénie et infections (MEPHI), and Institut de Recherche pour le Développement (IRD)-Aix Marseille Université (AMU)-Centre National de la Recherche Scientifique (CNRS)
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Thorax ,030213 general clinical medicine ,Cardiac output ,medicine.medical_specialty ,Critical Illness ,Ventricular Function, Left ,03 medical and health sciences ,0302 clinical medicine ,Intensive care ,Humans ,Medicine ,Pharmacology (medical) ,Simplified Acute Physiology Score ,Lung ultrasound score ,Original Research ,Retrospective Studies ,Ejection fraction ,Receiver operating characteristic ,business.industry ,SARS-CoV-2 ,Mortality rate ,COVID-19 ,Stroke Volume ,Retrospective cohort study ,General Medicine ,[SDV.SP]Life Sciences [q-bio]/Pharmaceutical sciences ,3. Good health ,Intensive Care Units ,Critical care ,ROC Curve ,Echocardiography ,030220 oncology & carcinogenesis ,Emergency medicine ,France ,business - Abstract
Introduction Severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) outbreaks have led to massive admissions to intensive care units (ICUs). An ultrasound examination of the thorax is widely performed on admission in these patients. The primary objective of our study was to assess the performance of the lung ultrasound score (LUS) on ICU admission to predict the 28-day mortality rate in patients with SARS-CoV-2. The secondary objective was to asses the performance of thoracic ultrasound and biological markers of cardiac injury to predict mortality. Methods This multicentre, retrospective, observational study was conducted in six ICUs of four university hospitals in France from 15 March to 3 May 2020. Patients admitted to ICUs because of SARS-CoV-2-related acute respiratory failure and those who received an LUS examination at admission were included. The area under the receiver-operating characteristics (ROC) curve was determined for the LUS score to predict the 28-day mortality rate. The same analysis was performed for the Simplified Acute Physiology Score, left ventricular ejection fraction, cardiac output, brain natriuretic peptide and ultra-sensitive troponin levels at admission. Results In 57 patients, the 28-day mortality rate was 21%. The area under the ROC curve of the LUS score value on ICU admission was 0.68 [95% CI 0.54–0.82; p = 0.05]. In non-intubated patients on ICU admission (n = 40), the area under the ROC curves was 0.84 [95% CI 0.70–0.97; p = 0.005]. The best cut-off of 22 corresponded to 85% specificity and 83% sensitivity. Conclusions LUS scores on ICU admission for SARS-CoV-2 did not efficiently predict the 28-day mortality rate. Performance was better for non-intubated patients at admission. Performance of biological cardiac markers may be equivalent to the LUS score. Supplementary Information The online version contains supplementary material available at 10.1007/s12325-021-01702-0.
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- 2021
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4. Guidelines for the management of women with severe pre-eclampsia
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Chloé Arthuis, Paul Berveiller, Florent Fuchs, Lionel Bouvet, Max Gonzalez Estevez, Catherine Fischer, Marie-Pierre Bonnet, Tiphaine Raia-Barjat, Thomas Schmitz, Marc Garnier, Vincent Compère, Céline Camilleri, Marie-Victoire Senat, Edouard Lecarpentier, Marie Bruyère, Valentina Faitot, Adeline Castel, H. Keita, Elodie Clouqueur, A. Rigouzzo, Julien Burey, Laurent Zieleskiewicz, Emmanuel Simon, Alexandre J Vivanti, Mathias Rossignol, Loïc Sentilhes, Florence Vial, Agnès Le Gouez, CHU Trousseau [APHP], Assistance publique - Hôpitaux de Paris (AP-HP) (AP-HP)-Sorbonne Université (SU), CHU Tenon [AP-HP], CHU Necker - Enfants Malades [AP-HP], Assistance publique - Hôpitaux de Paris (AP-HP) (AP-HP), UNIROUEN - UFR Santé (UNIROUEN UFR Santé), Université de Rouen Normandie (UNIROUEN), Normandie Université (NU)-Normandie Université (NU), Service de Gynécologie-Obstétrique et Médecine de la Reproduction [CHU Nantes] (Hôpital Mère- Enfant), Hôpital Mère Enfant CHU Nantes-Centre hospitalier universitaire de Nantes (CHU Nantes), Physiopathologie des Adaptations Nutritionnelles (PhAN), Université de Nantes - UFR de Médecine et des Techniques Médicales (UFR MEDECINE), Université de Nantes (UN)-Université de Nantes (UN)-Institut National de Recherche pour l’Agriculture, l’Alimentation et l’Environnement (INRAE), INSERM U1059, SAINBIOSE - Santé, Ingénierie, Biologie, Saint-Etienne (SAINBIOSE-ENSMSE), Centre Ingénierie et Santé (CIS-ENSMSE), École des Mines de Saint-Étienne (Mines Saint-Étienne MSE), Institut Mines-Télécom [Paris] (IMT)-Institut Mines-Télécom [Paris] (IMT)-École des Mines de Saint-Étienne (Mines Saint-Étienne MSE), Institut Mines-Télécom [Paris] (IMT)-Institut Mines-Télécom [Paris] (IMT)-Université Jean Monnet - Saint-Étienne (UJM)-Institut National de la Santé et de la Recherche Médicale (INSERM), Service de gynécologie et obstétrique [CHI Poissy-Saint Germain], CHI Poissy-Saint-Germain, Biologie de la Reproduction, Environnement, Epigénétique & Développement (BREED), École nationale vétérinaire - Alfort (ENVA)-Université de Versailles Saint-Quentin-en-Yvelines (UVSQ)-Université Paris-Saclay-Institut National de Recherche pour l’Agriculture, l’Alimentation et l’Environnement (INRAE), Hospices Civils de Lyon (HCL), AP-HP Hôpital Bicêtre (Le Kremlin-Bicêtre), Pôle Anesthésie Réanimation [CHU de Toulouse], Centre Hospitalier Universitaire de Toulouse (CHU Toulouse), Centre Hospitalier Tourcoing, Hôpital Jeanne de Flandre [Lille], Department of Anesthesiology, Intensive care and Perioperative medicine - Hautepierre Hospital, Strasbourg, Hôpital Cochin [AP-HP], Centre Hospitalier Régional Universitaire [Montpellier] (CHRU Montpellier), Institut Desbrest de santé publique (IDESP), Institut National de la Santé et de la Recherche Médicale (INSERM)-Université de Montpellier (UM), CHI Créteil, AP-HP - Hôpital Antoine Béclère [Clamart], Hôpital Lariboisière-Fernand-Widal [APHP], Centre Hospitalier Universitaire de Dijon - Hôpital François Mitterrand (CHU Dijon), Centre Hospitalier Régional Universitaire de Nancy (CHRU Nancy), Aix Marseille Université (AMU), Centre de Recherche Épidémiologie et Statistique Sorbonne Paris Cité (CRESS (U1153 / UMR_A_1125 / UMR_S_1153)), Conservatoire National des Arts et Métiers [CNAM] (CNAM), HESAM Université - Communauté d'universités et d'établissements Hautes écoles Sorbonne Arts et métiers université (HESAM)-HESAM Université - Communauté d'universités et d'établissements Hautes écoles Sorbonne Arts et métiers université (HESAM)-Université Sorbonne Paris Cité (USPC)-Institut National de la Santé et de la Recherche Médicale (INSERM)-Université Paris Cité (UPCité)-Institut National de Recherche pour l’Agriculture, l’Alimentation et l’Environnement (INRAE), Equipe 1 : EPOPé - Épidémiologie Obstétricale, Périnatale et Pédiatrique (CRESS - U1153), HESAM Université - Communauté d'universités et d'établissements Hautes écoles Sorbonne Arts et métiers université (HESAM)-HESAM Université - Communauté d'universités et d'établissements Hautes écoles Sorbonne Arts et métiers université (HESAM)-Université Sorbonne Paris Cité (USPC)-Institut National de la Santé et de la Recherche Médicale (INSERM)-Université Paris Cité (UPCité)-Institut National de Recherche pour l’Agriculture, l’Alimentation et l’Environnement (INRAE)-Conservatoire National des Arts et Métiers [CNAM] (CNAM), CHU Bordeaux [Bordeaux], BREED, INRAE, Sorbonne Université (SU)-Assistance publique - Hôpitaux de Paris (AP-HP) (AP-HP), Université Jean Monnet [Saint-Étienne] (UJM)-Institut National de la Santé et de la Recherche Médicale (INSERM)-Centre Ingénierie et Santé (CIS-ENSMSE), Institut Mines-Télécom [Paris] (IMT)-Institut Mines-Télécom [Paris] (IMT), Université Paris-Saclay-Institut National de Recherche pour l’Agriculture, l’Alimentation et l’Environnement (INRAE)-École nationale vétérinaire d'Alfort (ENVA)-Université de Versailles Saint-Quentin-en-Yvelines (UVSQ), CHU de Toulouse, Pole d'anesthésie Réanimation, Hôpital Paule de Viguier, Toulouse F-31059, France, CHU Toulouse [Toulouse], Conservatoire National des Arts et Métiers [CNAM] (CNAM)-Université Sorbonne Paris Cité (USPC)-Institut National de la Santé et de la Recherche Médicale (INSERM)-Université de Paris (UP)-Institut National de Recherche pour l’Agriculture, l’Alimentation et l’Environnement (INRAE), Conservatoire National des Arts et Métiers [CNAM] (CNAM)-Université Sorbonne Paris Cité (USPC)-Institut National de la Santé et de la Recherche Médicale (INSERM)-Université de Paris (UP)-Institut National de Recherche pour l’Agriculture, l’Alimentation et l’Environnement (INRAE)-Conservatoire National des Arts et Métiers [CNAM] (CNAM)-Université Sorbonne Paris Cité (USPC)-Institut National de la Santé et de la Recherche Médicale (INSERM)-Université de Paris (UP)-Institut National de Recherche pour l’Agriculture, l’Alimentation et l’Environnement (INRAE), and Santé Ingénierie Biologie Saint-Etienne (SAINBIOSE)
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medicine.medical_specialty ,[SDV]Life Sciences [q-bio] ,Neonatal morbidity ,Maternal morbidity ,Guidelines ,Critical Care and Intensive Care Medicine ,03 medical and health sciences ,0302 clinical medicine ,medicine ,Grading (education) ,030219 obstetrics & reproductive medicine ,Eclampsia ,business.industry ,Moderate level ,General Medicine ,Evidence-based medicine ,medicine.disease ,Severe preeclampsia ,3. Good health ,Quality of evidence ,[SDV] Life Sciences [q-bio] ,Anesthesiology and Pain Medicine ,Family medicine ,Severe pre-eclampsia ,business ,030217 neurology & neurosurgery - Abstract
Objective To provide national guidelines for the management of women with severe pre-eclampsia. Design A consensus committee of 26 experts was formed. A formal conflict-of-interest (COI) policy was developed at the onset of the process and enforced throughout. The entire guidelines process was conducted independently of any industrial funding. The authors were advised to follow the principles of the Grading of Recommendations Assessment, Development and Evaluation (GRADE®) system to guide assessment of quality of evidence. The potential drawbacks of making strong recommendations in the presence of low-quality evidence were emphasised. Methods The last SFAR and CNGOF guidelines on the management of women with severe pre-eclampsia were published in 2009. The literature is now sufficient for an update. The aim of this expert panel guidelines is to evaluate the impact of different aspects of the management of women with severe preeclampsia on maternal and neonatal morbidities separately. The experts studied questions within 7 domains. Each question was formulated according to the PICO (Patients Intervention Comparison Outcome) model and the evidence profiles were produced. An extensive literature review and recommendations were carried out and analysed according to the GRADE® methodology. Results The SFAR/CNGOF experts panel provided 25 recommendations: 8 have a high level of evidence (GRADE 1+/−), 9 have a moderate level of evidence (GRADE 2+/−), and for 7 recommendations, the GRADE method could not be applied, resulting in expert opinions. No recommendation was provided for 3 questions. After one scoring round, strong agreement was reached between the experts for all the recommendations. Conclusions There was strong agreement among experts who made 25 recommendations to improve practices for the management of women with severe pre-eclampsia.
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- 2021
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5. How can we minimize the potential risk of viral contamination during laparoscopic procedures for suspected or infected COVID-19 patients?
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Lionel Bouvet, Gautier Chene, Erdogan Nohuz, Emanuele Cerruto, Ciblage thérapeutique en Oncologie (EA3738), Université Claude Bernard Lyon 1 (UCBL), and Université de Lyon-Université de Lyon
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Adult ,medicine.medical_specialty ,Coronavirus disease 2019 (COVID-19) ,Severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) ,[SDV]Life Sciences [q-bio] ,Viral transmission ,Air Pollutants, Occupational ,Review Article ,030230 surgery ,03 medical and health sciences ,0302 clinical medicine ,Occupational Exposure ,Obstetrics and Gynaecology ,Disease Transmission, Infectious ,Humans ,Medicine ,Laparoscopy ,Intensive care medicine ,Aerosol ,Smoke ,Inhalation Exposure ,030219 obstetrics & reproductive medicine ,medicine.diagnostic_test ,SARS-CoV-2 ,business.industry ,Potential risk ,Filter ,Obstetrics and Gynecology ,3. Good health ,Surgical smoke ,Reproductive Medicine ,Female ,business ,Viral contamination ,Covid-19 ,Filtration - Abstract
Several societies have raised the risk of viral transmission of SARS-Cov-2 due to surgical smoke during laparoscopic procedures in infected patients. We propose to discuss this issue and to describe specific measures during laparoscopic procedures and a new homemade closed filtration system for smoke evacuation. Since the outbreak of COVID-19, performing a laparoscopy should meet multi-modal requirements. Surgical smoke evacuation device may be an effective tool in reducing exposure to surgical smoke and aerosols.
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- 2020
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6. Technics to put on and remove personal protective equipment before surgical or obstetrical procedure in suspected or infected COVID-19 patients (with video)
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Dominique Chassard, Lionel Bouvet, Gautier Chene, Emanuele Cerruto, Manon Curtis, Anthony Atallah, Oriane Bernigaud, Erdogan Nohuz, Pascal Fascia, Université Claude Bernard Lyon 1 (UCBL), and Université de Lyon
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2019-20 coronavirus outbreak ,Infectious Disease Transmission, Patient-to-Professional ,Coronavirus disease 2019 (COVID-19) ,Severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) ,[SDV]Life Sciences [q-bio] ,Pneumonia, Viral ,Obstetric Surgical Procedures ,Article ,Gynecologic surgical procedures ,Betacoronavirus ,03 medical and health sciences ,Gynecologic Surgical Procedures ,0302 clinical medicine ,Personal protective equipment ,Daily practice ,Obstetrics and Gynaecology ,Health care ,Humans ,Medicine ,Surgical clothes ,Pandemics ,030219 obstetrics & reproductive medicine ,SARS-CoV-2 ,business.industry ,COVID-19 ,Obstetrics and Gynecology ,medicine.disease ,3. Good health ,Coronavirus ,Occupational Diseases ,Reproductive Medicine ,030220 oncology & carcinogenesis ,Medical emergency ,Coronavirus Infections ,business - Abstract
Coronavirus pandemic is widely changing our professional daily practice and preventive measures must be taken and taught. Before any planned gynaecological or obstetric surgery, specific technics to put on and safely remove personal protective equipment should be implemented in order to avoid any contamination for both patients and healthcare workers.
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- 2020
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7. Comment je fais… simplement une cœlioscopie basse pression
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Dominique Chassard, Gautier Chene, Gery Lamblin, Lionel Bouvet, K Lebail-Carval, P. Chabert, Erdogan Nohuz, Université Claude Bernard Lyon 1 (UCBL), Université de Lyon, Ciblage thérapeutique en Oncologie (EA3738), and Université de Lyon-Université de Lyon
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medicine.medical_specialty ,medicine.diagnostic_test ,business.industry ,[SDV]Life Sciences [q-bio] ,Outpatient surgery ,Obstetrics and Gynecology ,030230 surgery ,medicine.disease ,Surgery ,03 medical and health sciences ,0302 clinical medicine ,Reproductive Medicine ,Pneumoperitoneum ,medicine ,Surgical anesthesia ,business ,Laparoscopy - Published
- 2020
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8. Coagulation changes and thromboembolic risk in COVID-19 obstetric patients
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Dan Benhamou, Hawa Keita, Anne Sophie Ducloy-Bouthors, Marie Pïerre Bonnet, Martine Bonnin, Anne Sophie Bouthors, Lionel Bouvet, Adeline Castel, Dominique Chassard, Pierre Yves Dewandre, Catherine Fisher, Benjamin Julliac, Frédéric J. Mercier, Estelle Morau, Thibault Rackelboom, Florence Vial, Anne Wernet, Université de Paris (UP), CHU Necker - Enfants Malades [AP-HP], Assistance publique - Hôpitaux de Paris (AP-HP) (AP-HP), Pharmacologie et évaluations thérapeutiques chez l'enfant et la femme enceinte (URP_7323), Groupe de Recherche sur les formes Injectables et les Technologies Associées - ULR 7365 (GRITA), Centre Hospitalier Régional Universitaire [Lille] (CHRU Lille)-Université de Lille, Université Paris Cité (UPCité), and Université de Lille-Centre Hospitalier Régional Universitaire [Lille] (CHRU Lille)
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medicine.medical_treatment ,[SDV]Life Sciences [q-bio] ,Critical Care and Intensive Care Medicine ,Plasma ,0302 clinical medicine ,Pregnancy ,Thrombophilia ,030212 general & internal medicine ,Pregnancy Complications, Infectious ,Disseminated intravascular coagulation ,medicine.diagnostic_test ,Obstetrics ,Blood Proteins ,General Medicine ,3. Good health ,hypercoagulability ,Tranexamic Acid ,Coagulation ,Female ,Partial Thromboplastin Time ,fibrinolysis ,Coronavirus Infections ,Cytokine Release Syndrome ,Tranexamic acid ,Partial thromboplastin time ,medicine.drug ,medicine.medical_specialty ,Pneumonia, Viral ,Article ,Betacoronavirus ,03 medical and health sciences ,Thromboembolism ,regional anaesthesia ,Fibrinolysis ,medicine ,Humans ,coagulation ,Pandemics ,Autoantibodies ,SARS-CoV-2 ,business.industry ,Postpartum Hemorrhage ,Pregnancy Complications, Hematologic ,Contraindications, Drug ,Anticoagulants ,COVID-19 ,Endothelial Cells ,030208 emergency & critical care medicine ,Puerperal Disorders ,Disseminated Intravascular Coagulation ,Heparin, Low-Molecular-Weight ,medicine.disease ,Cerebrovascular Disorders ,Anesthesiology and Pain Medicine ,(haemorrhage) ,business ,Postpartum period - Abstract
Thromboembolic events may occur both during and after pregnancy Pregnancy in itself increases the thromboembolic risk, which is even greater during the postpartum period Due to additional coagulation changes induced by COVID-19 infection, this risk may even be greater
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- 2020
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9. Identification of risk factors for postpartum urinary retention following vaginal deliveries: A retrospective case-control study
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Muriel Doret-Dion, Gautier Chene, Gery Lamblin, Roxana Soare, Lionel Bouvet, Camille Aeberli, Stephanie Moret, Université Claude Bernard Lyon 1 (UCBL), Université de Lyon, Application des ultrasons à la thérapie (LabTAU), Centre Léon Bérard [Lyon]-Université Claude Bernard Lyon 1 (UCBL), Université de Lyon-Université de Lyon-Institut National de la Santé et de la Recherche Médicale (INSERM), Hôpital Femme Mère Enfant [CHU - HCL] (HFME), Hospices Civils de Lyon (HCL), and CCSD, Accord Elsevier
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Adult ,medicine.medical_specialty ,[SDV]Life Sciences [q-bio] ,Perineum ,Logistic regression ,Young Adult ,03 medical and health sciences ,0302 clinical medicine ,Obstetrics and gynaecology ,Pregnancy ,medicine ,Edema ,Humans ,030212 general & internal medicine ,Vaginal delivery ,Retrospective Studies ,Hematoma ,030219 obstetrics & reproductive medicine ,Urinary retention ,business.industry ,Obstetrics ,Medical record ,Case-control study ,Obstetrics and Gynecology ,Extraction, Obstetrical ,Puerperal Disorders ,Urinary Retention ,Delivery, Obstetric ,University hospital ,3. Good health ,[SDV] Life Sciences [q-bio] ,Postpartum urinary retention ,Reproductive Medicine ,Risk factors ,Episiotomy ,Case-Control Studies ,Female ,Vulvar Diseases ,medicine.symptom ,business ,Complication ,Bladder dysfunction - Abstract
International audience; Objective: Postpartum urinary retention (PUR) is an uncommon complication of vaginal delivery, defined as a failure to void spontaneously in the six hours following vaginal birth. The objective of this study was to identify risk factors for PUR in order to provide prompt management.Study design: A retrospective, comparative, case-control study, including two groups of 96 patients who delivered vaginally, was conducted at the Women and Children's University Hospital in Lyon, France. Patients were selected based on data extraction from the medical records of the obstetrics and gynecology department. The first group included patients with postpartum urinary retention and the second group, without PUR, was selected randomly, respecting 1:1 matching criteria, paired according to the year of delivery and patient's age at delivery.Results: Logistic regression analysis found that instrumental delivery (OR 13.42, 95%CI [3.34;53.86], p = 0.0002), absence of spontaneous voiding before leaving the delivery room (OR 6.14, 95%CI [2.56;14.73], p < 0.0001), no intact perineum (OR 3.29, 95%CI [1.10;9.90], p = 0.03) and vulvar edema or perineal hematoma (OR 8.05, 95%CI [1.59;40.67], p = 0.01) were independent risk factors associated with PUR.Conclusion: The present study identified risk factors for PUR that should be taken into consideration as soon as delivery is over in order to implement appropriate management. Future studies are needed to assess the contribution of early systematic bladder scanning in patients with risk factors for early diagnosis of PUR.
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- 2019
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10. Retrospective cohort study of decision-to-delivery interval and neonatal outcomes according to the type of anaesthesia for code-red emergency caesarean sections in a tertiary care obstetric unit in France
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Dominique Chassard, Cyril Bidon, Lionel Bouvet, Anne-Charlotte Riegel, Bernard Allaouchiche, François-Pierrick Desgranges, Université Claude Bernard Lyon 1 (UCBL), and Université de Lyon
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Adult ,Anesthesia, Epidural ,Time Factors ,Sedation ,medicine.medical_treatment ,[SDV]Life Sciences [q-bio] ,Anesthesia, General ,Critical Care and Intensive Care Medicine ,Tertiary care ,Hospitals, University ,Tertiary Care Centers ,03 medical and health sciences ,0302 clinical medicine ,Pregnancy ,Anesthesia, Obstetrical ,Humans ,Medicine ,General anaesthesia ,Caesarean section ,030212 general & internal medicine ,Obstetrics and Gynecology Department, Hospital ,reproductive and urinary physiology ,Retrospective Studies ,Cesarean Section ,business.industry ,Medical record ,Infant, Newborn ,Pregnancy Outcome ,Lidocaine ,Analgesia, Patient-Controlled ,030208 emergency & critical care medicine ,Retrospective cohort study ,General Medicine ,3. Good health ,Analgesia, Epidural ,Pregnancy Complications ,Anesthesiology and Pain Medicine ,Neonatal outcomes ,Anesthesia ,Female ,Apgar score ,France ,Emergencies ,medicine.symptom ,business - Abstract
Background Non-elective caesarean sections may be classified using a three-colour coding system, from code-green caesarean section corresponding to non-urgent delivery (no maternal of foetal compromise) to code-red caesarean section corresponding to emergency caesarean section due to immediate life-threatening maternal or foetal situations. Decision-to-delivery interval ≤ 15 min has been advocated in France for code-red caesarean section. This retrospective cohort study aimed to assess the decision-to-delivery interval and the neonatal outcomes according to the anaesthetic technique performed for code red caesarean section in a French tertiary care obstetric unit. Methods All women undergoing code-red caesarean section between January 2013 and December 2015 were included. Demographic characteristics and anaesthetic, obstetrical and neonatal outcomes were collected from the patient's electronic medical records. Results Among 194 code-red caesarean sections analysed, 127 (65%) were performed under epidural anaesthesia and 67 (35%) under primary general anaesthesia. The median decision-to-delivery interval was 10 [8–12.5] min, and the interval was ≤ 15 min in 174 (90%) women. Effective epidural top-up and epidural top-up requiring supplemental sedation were associated with the shortest decision-to-delivery interval. Primary general anaesthesia was independently associated with depressed 5 minutes Apgar score. Conclusion The decision-to-delivery interval was ≤ 15 min in most women, suggesting that optimised organisation ensures short decision-to-delivery interval independently of the anaesthetic technique performed. As general anaesthesia was associated with worse neonatal outcomes, our results support the early insertion of an epidural catheter whenever there is any potential concern that an emergency caesarean section may be required.
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- 2019
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11. Reliability of gastric suctioning compared with ultrasound assessment of residual gastric volume: a prospective multicentre cohort study
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Lionel Bouvet, Marc Leone, Dominique Chassard, E. Loubradou, Laurent Zieleskiewicz, J. Morel, A. Alain, Bernard Allaouchiche, L. Argaud, Service Anesthésie et Réanimation [Hôpital Nord - APHM], Aix Marseille Université (AMU)-Assistance Publique - Hôpitaux de Marseille (APHM)- Hôpital Nord [CHU - APHM], Hôpital Edouard Herriot, Service Anesthésie Réanimation, Hôpital Edouard Herriot [CHU - HCL], Hospices Civils de Lyon (HCL)-Hospices Civils de Lyon (HCL), Hôpital Femme Mère Enfant [CHU - HCL] (HFME), Hospices Civils de Lyon (HCL), Microbes évolution phylogénie et infections (MEPHI), Institut de Recherche pour le Développement (IRD)-Aix Marseille Université (AMU)-Centre National de la Recherche Scientifique (CNRS), Hopital Civil, and Centre National de la Recherche Scientifique (CNRS)-Institut de Recherche pour le Développement (IRD)-Aix Marseille Université (AMU)
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Male ,Enteral administration ,Cohort Studies ,Respiratory Aspiration of Gastric Contents ,0302 clinical medicine ,030202 anesthesiology ,[SDV.MHEP.MI]Life Sciences [q-bio]/Human health and pathology/Infectious diseases ,Medicine ,Prospective Studies ,030212 general & internal medicine ,Intubation, Gastrointestinal ,Antrum ,ComputingMilieux_MISCELLANEOUS ,Ultrasonography ,[SDV.MHEP.ME]Life Sciences [q-bio]/Human health and pathology/Emerging diseases ,Stomach ,digestive, oral, and skin physiology ,Ultrasound ,Ventilator-associated pneumonia ,Middle Aged ,Gastrointestinal Contents ,Anti-Bacterial Agents ,Erythromycin ,3. Good health ,medicine.anatomical_structure ,[SDV.MP.VIR]Life Sciences [q-bio]/Microbiology and Parasitology/Virology ,Vomiting ,Female ,medicine.symptom ,medicine.drug ,Cohort study ,Adult ,Suction ,03 medical and health sciences ,[SDV.MHEP.CSC]Life Sciences [q-bio]/Human health and pathology/Cardiology and cardiovascular system ,Monitoring, Intraoperative ,Humans ,[SDV.MP.PAR]Life Sciences [q-bio]/Microbiology and Parasitology/Parasitology ,Aged ,business.industry ,Reproducibility of Results ,medicine.disease ,[SDV.MP.BAC]Life Sciences [q-bio]/Microbiology and Parasitology/Bacteriology ,digestive system diseases ,Anesthesiology and Pain Medicine ,Gastric Emptying ,business ,Nuclear medicine - Abstract
We aimed to compare the reliability of aspiration via a nasogastric tube with ultrasound for assessment of residual gastric volume. Sixty-one adult patients who were mechanically ventilated and received continuous enteral feeding through a nasogastric tube for > 48 h were included. A first qualitative and quantitative ultrasound examination of the gastric antrum was followed by gastric suctioning, performed by an operator blinded to the result of the ultrasound examination. A second ultrasound examination was performed thereafter, followed by re-injection of the aspirated gastric contents (≤ 250 ml) into the stomach. A third ultrasound assessment was then immediately performed. If the suctioned volume was ≥ 250 ml, 250 mg erythromycin was infused over 30 min. A fourth ultrasound was performed 90 min after the third. Sixty (98%) patients had a qualitatively assessed full stomach at first ultrasound examination vs. 52 (85%) after gastric suctioning (p = 0.016). The calculated gastric volume significantly decreased after gastric suctioning, without a significant decrease in the number of patients with volume ≥ 250 ml. Four of the nine patients with calculated gastric volume ≥ 250 ml had vomiting within the last 24 h (p = 0.013). The antral cross-sectional area significantly decreased between the third and the fourth ultrasound examination (p = 0.015). Erythromycin infusion did not make a significant difference to gastric volume (n = 10). Our results demonstrate that gastric suctioning is not a reliable tool for monitoring residual gastric volume. Gastric ultrasound is a feasible and promising tool for gastric volume monitoring in clinical practice.
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- 2019
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12. Can point-of-care ultrasound predict spinal hypotension during caesarean section? A prospective observational study
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Sharon Einav, Malik Haddam, Juliette Blanc, Laurent Zieleskiewicz, A. Delmas, A. Bourgoin, Marc Leone, C. Bechis, A. Mignon, A. Noel, Anderson Loundou, Lionel Bouvet, Gary Duclos, Laboratoire Physico-Chimie Curie [Institut Curie] (PCC), Institut Curie [Paris]-Institut de Chimie du CNRS (INC)-Sorbonne Université (SU)-Centre National de la Recherche Scientifique (CNRS), Service Anesthésie et Réanimation [Hôpital Nord - APHM], Aix Marseille Université (AMU)-Assistance Publique - Hôpitaux de Marseille (APHM)- Hôpital Nord [CHU - APHM], Centre d'études et de recherche sur les services de santé et la qualité de vie (CEReSS), Aix Marseille Université (AMU), Imagerie médicale, Université Bordeaux Segalen - Bordeaux 2-CHU Bordeaux [Bordeaux], AP-HP - Hôpital Cochin Broca Hôtel Dieu [Paris], Assistance publique - Hôpitaux de Paris (AP-HP) (AP-HP), Microbes évolution phylogénie et infections (MEPHI), Institut de Recherche pour le Développement (IRD)-Aix Marseille Université (AMU)-Centre National de la Recherche Scientifique (CNRS), ID RCB 2015-A00314-45, Assistance Publique Hôpitaux de Marseille, Institut des Sciences Chimiques de Rennes (ISCR), Centre National de la Recherche Scientifique (CNRS)-Institut de Chimie du CNRS (INC)-Université de Rennes 1 (UR1), Université de Rennes (UNIV-RENNES)-Université de Rennes (UNIV-RENNES)-Ecole Nationale Supérieure de Chimie de Rennes (ENSCR)-Institut National des Sciences Appliquées - Rennes (INSA Rennes), Institut National des Sciences Appliquées (INSA)-Université de Rennes (UNIV-RENNES)-Institut National des Sciences Appliquées (INSA), Systèmes de Référence Temps Espace (SYRTE), Institut national des sciences de l'Univers (INSU - CNRS)-Observatoire de Paris, and Université Paris sciences et lettres (PSL)-Université Paris sciences et lettres (PSL)-Sorbonne Université (SU)-Centre National de la Recherche Scientifique (CNRS)
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Adult ,maternal hypotension ,Point-of-Care Systems ,medicine.medical_treatment ,Fluid responsiveness ,[SDV.MHEP.CHI]Life Sciences [q-bio]/Human health and pathology/Surgery ,[SDV.MHEP.GEO]Life Sciences [q-bio]/Human health and pathology/Gynecology and obstetrics ,Anesthesia, Spinal ,03 medical and health sciences ,transthoracic echocardiography ,0302 clinical medicine ,Predictive Value of Tests ,Pregnancy ,030202 anesthesiology ,Hypovolemia ,Anesthesia, Obstetrical ,Humans ,Medicine ,Caesarean section ,Prospective Studies ,030212 general & internal medicine ,point-of-care ultrasound ,Sympathetic tone ,Ultrasonography ,030219 obstetrics & reproductive medicine ,Receiver operating characteristic ,Cesarean Section ,business.industry ,Point of care ultrasound ,Ultrasound ,passive leg raising ,Heart ,030208 emergency & critical care medicine ,Anesthesiology and Pain Medicine ,Echocardiography ,Maternal Hypotension ,Anesthesia ,caesarean section ,spinal anaesthesia: complications ,Female ,Observational study ,Hypotension ,medicine.symptom ,business - Abstract
International audience; Spinal anaesthesia for elective caesarean section is associated with maternal hypotension, secondary to alteration of sympathetic tone and hypovolemia, in up to 70% of cases. Measurement of the subaortic variation in the velocity time integral (VTI) after passive leg raising allows prediction of fluid responsiveness. Our objective, in this prospective single-centre observational study, was to assess the ability of change in VTI after 45 degrees passive leg raising to predict hypotension after spinal anaesthesia. Ultrasound measurements were performed just before elective caesarean section. Anaesthesia, intravenous coloading and prophylactic vasopressor treatment were standardised according to current guidelines. We studied 40 women. Hypotension occurred in 17 (45%) women. The area (95%CI) under the receiver operating characteristics (ROC) curve for the prediction of spinal hypotension was 0.8 (0.6-0.9; p = 0.0001). Seventeen women had a change in VTI with leg elevation 8%, which was predictive for not developing hypotension, and 11 had a change 21%, predictive for hypotension. The grey zone between 8% and 21%, with inconclusive values, included 12 women. We suggest that cardiac ultrasound provides characterisation of the risk of hypotension following spinal anaesthesia at elective caesarean section, and therefore may allow individualised strategies for prevention and management.
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- 2018
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