1. Incidence of childhood leukaemia and non-Hodgkin's lymphoma in France: National Registry of Childhood Leukaemia and Lymphoma, 1990-1999
- Author
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Stéphanie Bellec, Brigitte Nelken, Denis Hémon, Guy Leverger, Jacqueline Clavel, Marie-Françoise Auclerc, Etienne Vilmer, C Waterkeyn, André Baruchel, A. Goubin, Anne Auvrignon, Catherine Patte, Danièle Sommelet, Nathalie Philippe, F Perrillat-Menegaux, Recherches épidémiologiques et statistiques sur l'environnement et la santé., Institut National de la Santé et de la Recherche Médicale (INSERM)-Institut National de la Santé et de la Recherche Médicale (INSERM), Groupe FRALLE, Groupe Hospitalier Saint Louis - Lariboisière - Fernand Widal [Paris], Assistance publique - Hôpitaux de Paris (AP-HP) (AP-HP)-Assistance publique - Hôpitaux de Paris (AP-HP) (AP-HP), CHU Trousseau [APHP], Assistance publique - Hôpitaux de Paris (AP-HP) (AP-HP)-Sorbonne Université (SU), Children´s Leukaemia Cooperative Group (CLCG), EORTC, LMB, Institut Gustave Roussy (IGR), Service d'hématologie pédiatrique, Assistance publique - Hôpitaux de Paris (AP-HP) (AP-HP)-Assistance publique - Hôpitaux de Paris (AP-HP) (AP-HP)-Université Paris Diderot - Paris 7 (UPD7), Service d'hématologie-immunologie-oncologie pédiatrique [CHU Trousseau], Université Pierre et Marie Curie - Paris 6 (UPMC)-Assistance publique - Hôpitaux de Paris (AP-HP) (AP-HP)-CHU Trousseau [APHP], Assistance publique - Hôpitaux de Paris (AP-HP) (AP-HP)-Sorbonne Université (SU)-Sorbonne Université (SU), Service hématologie-oncologie pédiatrique, Hôpital Jeanne de Flandre [Lille], Service d'Hématologie Pédiatrique [CHRU Nancy], Centre Hospitalier Régional Universitaire de Nancy (CHRU Nancy), Service d'hématologie et immunologie pédiatrique, Assistance publique - Hôpitaux de Paris (AP-HP) (AP-HP)-Hôpital Robert Debré-Université Paris Diderot - Paris 7 (UPD7), Registre National des Hémopathies malignes de l'Enfant (RNHE), Institut de Veille Sanitaire (INVS)-Institut National de la Santé et de la Recherche Médicale (INSERM), Kaniewski, Nadine, Assistance publique - Hôpitaux de Paris (AP-HP) (AP-HP)-Université Paris Diderot - Paris 7 (UPD7)-Groupe Hospitalier Saint Louis - Lariboisière - Fernand Widal [Paris], and Assistance publique - Hôpitaux de Paris (AP-HP) (AP-HP)
- Subjects
Male ,Cancer Research ,Pediatrics ,Time Factors ,MESH: Registries ,Epidemiology ,Disease ,MESH: Research Support, Non-U.S. Gov't ,0302 clinical medicine ,MESH: Lymphoma, Non-Hodgkin ,immune system diseases ,MESH: Leukemia, Lymphocytic, Acute ,hemic and lymphatic diseases ,MESH: Child ,Registries ,030212 general & internal medicine ,MESH: Incidence ,Child ,education.field_of_study ,Leukemia ,Incidence ,Lymphoma, Non-Hodgkin ,Incidence (epidemiology) ,Precursor Cell Lymphoblastic Leukemia-Lymphoma ,MESH: Infant ,3. Good health ,Childhood leukaemia ,Haematopoiesis ,Oncology ,Child, Preschool ,030220 oncology & carcinogenesis ,Female ,France ,medicine.medical_specialty ,Adolescent ,Population ,[SDV.CAN]Life Sciences [q-bio]/Cancer ,03 medical and health sciences ,Sex Factors ,[SDV.CAN] Life Sciences [q-bio]/Cancer ,MESH: Sex Factors ,MESH: Leukemia ,medicine ,Humans ,education ,MESH: Adolescent ,MESH: Humans ,business.industry ,MESH: Time Factors ,MESH: Child, Preschool ,Public Health, Environmental and Occupational Health ,Infant ,medicine.disease ,MESH: Male ,Non-Hodgkin's lymphoma ,Lymphoma ,MESH: France ,[SDV.SPEE] Life Sciences [q-bio]/Santé publique et épidémiologie ,[SDV.SPEE]Life Sciences [q-bio]/Santé publique et épidémiologie ,National registry ,business ,MESH: Female ,MESH: Child, Prescho - Abstract
International audience; The French National Registry of Childhood Leukaemia and Lymphoma (NRCL) covers the whole French mainland population aged less than 15 years (approximately 11 million children) for all childhood haematopoietic tumours since 1 January 1990, except Hodgkin's disease, which has been registered since 1 January 1999. During the period from 1990 to 1999, 5757 cases of leukaemia, lymphoma and myelodysplastic syndrome were registered in the NRCL, with an average of 2.5 sources per case. The age-standardized incidence rates per million per year were 43.1 for leukaemia (34.3 for acute lymphoblastic leukaemia, 7.1 for acute myeloblastic leukaemia, 0.6 for chronic myeloid leukaemia and 0.5 for chronic myelomonocytic leukaemia), 8.9 for non-Hodgkin's lymphomas and 6.7 for Hodgkin's disease. Down's syndrome was present in 110 cases of acute leukaemia (2.5%) and three cases of non-Hodgkin's lymphoma (0.3%). The incidence of acute lymphoblastic leukaemia showed a typical peak at age 2 years for girls and 3 years for boys. The incidence rates of leukaemia and non-Hodgkin's lymphoma did not show any temporal trends over the 10 year period.
- Published
- 2004