1. [Effects of 2450 MHz microwave on long-term potentiation of hippocampus and lipofuscin contents in rat brain].
- Author
-
Zhao YL, Peng XD, Yang YH, Ma HB, Song JP, and Pu JS
- Subjects
- Animals, Brain metabolism, Brain radiation effects, Dose-Response Relationship, Radiation, Learning radiation effects, Lipofuscin metabolism, Long-Term Potentiation physiology, Memory radiation effects, Rats, Rats, Wistar, Hippocampus physiology, Hippocampus radiation effects, Lipofuscin radiation effects, Long-Term Potentiation radiation effects, Microwaves
- Abstract
Objective: To study the mechanism of the effects of microwave on learning and memory., Method: Long-term potentiation (LTP) of hippocampus induced potential and lipofuscin content in rat brain were studied. After irradiated by a 2450 MHz microwave, rats hippocampus induced potential in vivo was recorded and lipofuscin content in the brain was measured by fluorospectrophotometry., Result: Continuous microwave with 10-25 mW/cm2 intensity could inhibit the amplitude of the population spike (PS) of weak and strong stimuli induced LTP with an intensity-effect relationship. At 25 mW/cm2, lipofuscin content was significantly higher than control and 10 mW/cm2 group (P<0.05)., Conclusion: Continuous microwave with 10-25 mW/cm2 intensity impairs learning and memory by restraining hippocampus LTP and brain lipofuscin content.
- Published
- 2004