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This study presents a theoretical study on the super thin and conductive thermal absorber with built-in corrugated channels on the basis of previous field experiments. The flow and heat transfer characteristics of the corrugated channels are simulated to identify the factors affecting photovoltaic/thermal (PV/T) system efficiency. The influences of the structural parameters such as the corrugation number, the corrugation area, and the flow channel width on the water outlet temperature and heat collection are discussed in order to support the structural optimization design of the hybrid PV/T system. The simulation results were validated to be in good agreement with experimental results. The results indicate that increasing inlet water velocity leads to a decrease in the outlet temperature. It was found that the corrugation area and the flow channel width have impacts on the outlet temperature of the hybrid PV/T collector panel. When the flow channel width of the absorber plate is reduced from 4 mm to 3 mm, the outlet temperature attained is between 298 and 302 K, and the heat collection is in the range of 16.2–51.4 MJ/h. This led to an increase in the amount of heat collected by 18.6%. [ABSTRACT FROM AUTHOR]

Bone resorption occurs after bone grafting, however, contemporaneous reconstruction of the innervation of the bone graft is a potential treatment to maintain the bone mass of the graft. The innervation of bone is an emerging research topic. To understand the potential molecular mechanisms of bone innervation after bone grafting, we collected normal iliac bone tissue as well as bone grafts with or without innervation from nine patients 1 year after surgery and performed RNA sequencing. We identified differentially expressed genes) from these samples and used the gene ontology and Kyoto Encyclopedia of Genes and Genomes databases for functional enrichment and signaling pathway analysis. In parallel, we established protein–protein interaction networks to screen functional modules. Based on bioinformatic results, we validated in vitro the osteogenic differentiation potential of rat bone marrow mesenchymal stem cells (BMMSCs) after calcitonin gene-related peptide (CGRP) stimulation and the expression of p38 MAPK and Wnt6/β-catenin pathways during osteogenesis. Our transcriptome analysis of bone grafts reveals functional modules and signaling pathways of innervation which play a vital role in the structural and functional integration of the bone graft. Simultaneously, we demonstrate that CGRP regulates the differentiation of BMMSCs through p38 MAPK and Wnt6/β-catenin. [ABSTRACT FROM AUTHOR]