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This paper presents the vegetation change trends and their causes in the Inner Mongolian Autonomous Region, China from 1982 to 2006. We used National Oceanic and Atmospheric Administration (NOAA) Advanced Very High Resolution Radiometer (AVHRR) data to determine the vegetation change trends based on regression model by fitting simple linear regression through the time series of the integrated Normalized Difference Vegetation Index (NDVI) in the growing season for each pixel and calculating the slopes. We also explored the relationship between vegetation change trends and climatic and anthropogenic factors. This paper indicated that a large portion of the study area (17%) had experienced a significant vegetation increase at the 0.05 level from 1982 to 2006. The significant vegetation increase showed no positive link with precipitation and was mainly caused by human activities. In or to the south of Horqin Sandy Land, in the Hetao Plain, and at the northern foothills of the YinshanMountain, the significant NDVI increase trends were mainly caused by the increase of the millet yield per unit of cropland. In the east of Ordos Plateau, the significant NDVI increase trends were mainly determined by the fencing and planting of grasses and trees on grassland. [ABSTRACT FROM AUTHOR]