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We investigate the mathematical correlation between weight loss and texture characteristics of modified atmosphere packaging (MAP) for cherry tomatoes (Solanum lycopersicum). In this study, the Slogstic1 model showed that the weight loss of cherry tomatoes with MAP increased with prolonged storage time at room temperature. Moreover, this weight loss had a negative influence on all the texture parameters. Taking weight loss as a dependent variable, the texture parameters of firmness, cohesiveness, gumminess, chewiness, and resilience were significantly related to weight loss as independent variables and used to establish the fitting functions. With an increase in weight loss, the changes in firmness, cohesiveness, gumminess, chewiness, and resilience were consistent with the Log3P1, Gauss, Logistic, Boltzmann, and GaussAmp models, respectively. The result will provide useful information for predicting the weight loss and evaluating the texture of MAP fruit quantitatively. Novelty impact statement: The weight loss of MAP cherry tomatoes conformed to the Slogstic1 growth model.The weight loss had the strongest negative correlation with firmness.With increasing weight loss, the changes in firmness, cohesiveness, gumminess, chewiness, and resilience matched the Log3P1, Gauss, Logistic, Boltzmann, and GaussAmp models, respectively. [ABSTRACT FROM AUTHOR]

We investigated the effect of Chinese herbal compound Song-you Yin on HCC stemness. MHCC97H and Hep3B cell lines were pretreated with SYY for 4 weeks, and their chemosensitivity to oxaliplatin was evaluated. The expression of CSC-related markers, cell invasion and migration, and colony formation were also examined. SYY-treated orthotopic nude mouse models of human HCC were developed to explore the effect of oxaliplatin on tumor growth, metastasis, and survival. The CSCrelated molecular changes in vivo were also evaluated. The result showed that MHCC97H and Hep3B cells pretreated with SYY showed significantly increased chemosensitivity to oxaliplatin and the downregulation of CSC-related markers CD90, CD24, and EPCA M. SYY also attenuated cell motility, invasion, and colony formation in MHCC97H and Hep3B cell lines. The reduced tumorigenicity and pulmonary metastasis were observed in SYY-pretreated cell lines. Combination treatment with oxaliplatin and SYY significantly reduced tumor volume and pulmonary metastasis and prolonged survival compared with oxaliplatin treatment alone. Immunohistochemical analysis showed reduced expression of CD90, ABCG2, ALDH, CD44, EPCA M, vimentin, and M MP- 9 and increased the expression of E-cadherin, in HCC cells following combination treatment. These data clearly demonstrate that SYY renders hepatocellular carcinoma sensitive to oxaliplatin through the inhibition of stemness. [ABSTRACT FROM AUTHOR]