1. Bioactivities of Compounds from Elephantopus scaber, an Ethnomedicinal Plant from Southwest China.
- Author
-
Jianjun Wang, Ping Li, Baosai Li, Zhiyong Guo, Kennelly, Edward J., and Chunlin Long
- Subjects
ANTIOXIDANTS ,CHROMATOGRAPHIC analysis ,MEDICINAL plants ,RESEARCH funding ,PLANT extracts ,FREE radical scavengers - Abstract
Elephantopus scaber is an ethnomedicinal plant used by the Zhuang people in Southwest China to treat headaches, colds, diarrhea, hepatitis, and bronchitis. A new δ-truxinate derivative, ethyl, methyl 3,4,3',4'-tetrahydroxy-δ-truxinate (1), was isolated from the ethyl acetate extract of the entire plant, along with 4 known compounds. The antioxidant activity of these 5 compounds was determined by ABTS radical scavenging assay. Compound 1 was also tested for its cytotoxicity effect against HepG2 byMTT assay (IC50 = 60μM), and its potential anti-inflammatory, antibiotic, and antitumor bioactivities were predicted using target fishing method software. [ABSTRACT FROM AUTHOR]
- Published
- 2014
- Full Text
- View/download PDF